
571-1. For safe use
1
For safety and security
RX450h_U_OM0E013U
Exhaust gas precautions
Harmful substance to the human body is contained in exhaust gases if inhaled.
WARNING
Exhaust gases contain harmful carbon monoxi de (CO), which is colorless and odorless.
Observe the following precautions.
Failure to do so may cause exhaust gases enter the vehicle and may lead to an accident
caused by light-headedness, or may lead to death or a serious health hazard.
■Important points while driving
●Keep the back door closed.
●If you smell exhaust gases in the vehicle even when the back door is closed, open the
windows and have the vehicle inspected at your Lexus dealer as soon as possible.
■When parking
●If the vehicle is in a poorly ventilated area or a closed area, such as a garage, stop the
hybrid system.
●Do not leave the vehicle with the hybrid system on for a long time.
If such a situation cannot be avoided, park the vehicle in an open space and ensure
that exhaust fumes do not enter the vehicle interior.
●Do not leave the hybrid system operating in an area with snow build-up, or where it is
snowing. If snowbanks build up around the vehicle while the hybrid system is operat-
ing, exhaust gases may collect and enter the vehicle.
■Exhaust pipe
The exhaust system needs to be checked periodically. If there is a hole or crack caused
by corrosion, damage to a joint or abnormal exhaust noise, be sure to have the vehicle
inspected and repaired by your Lexus dealer.

631-2. Child safety
1
For safety and security
RX450h_U_OM0E013U
WARNING
■When using a child restraint system
Observe the following precautions.
Failure to do so may result in death or serious injury.
●Never install a rear-facing child restraint system on the front passenger seat even if
the “AIR BAG OFF” indicator light is illuminated. In the even t of an accident, the force
of the rapid inflation of the front passenger airbag can cause death or serious injury to
the child if the rear-facing ch ild restraint system is installed on the front passenger
seat.
●A forward-facing child restraint system ma y be installed on the front passenger seat
only when it is unavoidable. A child restraint system that requires a top tether strap
should not be used in the front passenger seat since there is no top tether strap
anchor for the front passenger seat.
●A forward-facing child restraint system may
be installed on the front passenger seat only
when it is unavoidable. When installing a for-
ward-facing child restraint system on the front
passenger seat, raise the seatback as much as
possible, move the seat to the rearmost posi-
tion, and raise the seat to the highest position,
even if the “AIR BAG OFF” indicator light is
illuminated.
If the head restraint interferes with the instal-
lation of the child restraint system, and the
head restraint can be removed, remove the
head restraint.
If the head restraint cannot be removed, raise
it to the uppermost position.
●Do not allow the child to lean his/her head or
any part of his/her body against the door or
the area of the seat, front or rear pillars, or
roof side rails from which the SRS side air-
bags or SRS curtain shield airbags deploy
even if the child is seat ed in the child restraint
system. It is dangerous if the SRS side airbags
and curtain shield airbags inflate, and the
impact could cause death or serious injury to
the child.

791-3. Hybrid system
1
For safety and security
RX450h_U_OM0E013U
■Sounds and vibrations specific to a hybrid vehicle
There may be no engine sound or vibration even though the vehicle is able to move with
the “READY” indicator is illuminated. For safety, make sure to shift the shift lever to P and
apply the parking brake when parked.
The following sounds or vibrations may occu r when the hybrid system is operating and
are not a malfunction:
●Motor sounds may be heard from the engine compartment.
●Sounds may be heard from the hybrid battery (traction battery) behind the rear seats
when the hybrid system starts or stops.
●Relay operating sounds such as a snap or so ft clank will be emitted from the hybrid bat-
tery (traction battery), behind the rear se ats, when the hybrid system is started or
stopped.
●Sounds from the hybrid system may be heard when the back door is open.
●Sounds may be heard from the transmission wh en the gasoline engine starts or stops,
when driving at low spee ds, or during idling.
●Engine sounds may be heard when accelerating sharply.
●Sounds may be heard due to regenerative braking when the brake pedal is depressed
or as the accelerator pedal is released.
●Vibration may be felt when the ga soline engine starts or stops.
●Cooling fan sounds may be heard from th e air intake vents under the rear seats.
■Vehicle proximity notification system
In the following cases, the vehicle proximity notification system may be difficult for sur-
rounding people to hear.
●In very noisy areas
●In the wind or the rain
Also, as the vehicle proximity notification system is installed on the front of the vehicle, it
may be more difficult to hear from the re ar of the vehicle compared to the front.
■Maintenance, repair, recycling, and disposal
Contact your Lexus dealer regarding mainte nance, repair, recycling and disposal. Do
not dispose of the vehicle yourself.
■Customization
Some functions can be customized. ( P. 607)

801-3. Hybrid system
RX450h_U_OM0E013U
The illustration is an example for explanation and may differ from the actual item.
*:AWD models only
Hybrid system precautions
Take care when handling the hybrid system, as it is a high voltage system
(about 650 V at maximum) as well as contains parts that become extremely
hot when the hybrid system is operating. Obey the warning labels attached to
the vehicle.
Warning label
Hybrid battery (traction battery)
Rear electric motor (traction
motor)
*
Service plug High voltage cables (orange)
Front electric motor (traction
motor)
Power control unit
Air conditioning compressor
1
2
3
4
5
6
7
8

811-3. Hybrid system
1
For safety and security
RX450h_U_OM0E013U
The air intake/discharge vents for the
hybrid battery (traction battery) are
located under the rear seats and in lug-
gage compartment respectively. If the
air intake vents are blocked, it could
lead to a reduction in hybrid battery
(traction battery) output.
When a certain level of impact is detected by the impact sensor, the emergency
shut off system blocks the high voltage current and stops the fuel pump to mini-
mize the risk of electrocution and fuel leakage. If the emergency shut off system
activates, your vehicle will not restart. To restart the hybrid system, contact your
Lexus dealer.
A message is automatically displayed when a malfunction occurs in the hybrid
system or an improper operation is attempted.
If a warning message is shown on the
multi-information display, read the
message and follow the instructions.
( P. 543)
Hybrid battery (traction battery) air intake/discharge vents
Air intake vents
Air discharge vents
Emergency shut off system
Hybrid warning message

841-3. Hybrid system
RX450h_U_OM0E013U
WARNING
■Hybrid battery (traction battery)
●Never resell, hand over or modify the hybrid battery. To prevent accidents, hybrid
batteries that have been removed from a disposed vehicle are collected through
Lexus dealer. Do not dispose of the battery yourself.
Unless the battery is properly collected, the following may occur, resulting in death
or serious injury:
• The hybrid battery may be illegally disposed of or dumped, and it is hazardous to
the environment or someone may touch a high voltage part, resulting in an electric
shock.
• The hybrid battery is intended to be used exclusively with your hybrid vehicle. If the hybrid battery is used outside of your vehicle or modified in any way, accidents
such as electric shock, heat generation , smoke generation, an explosion and elec-
trolyte leakage may occur.
When reselling or handing over your vehicle, the possibility of an accident is
extremely high because the person receiving the vehicle may not be aware of these
dangers.
●If your vehicle is disposed of without the hybrid battery having been removed, there is
a danger of serious electric shock if high voltage parts, cables and their connectors
are touched. In the event that your vehicle must be disposed of, the hybrid battery
must be disposed of by your Lexus dealer or a qualified service shop. If the hybrid bat-
tery is not disposed of properly, it may cause electric shock that can result in death or
serious injury.
NOTICE
■Hybrid battery (traction battery) air intake/discharge vents
●Do not place objects that will block the air intake vents. The hybrid battery (traction
battery) may overheat and be damaged.
●Clean the air intake/discharge vents regularl y to prevent the hybrid battery (traction
battery) from overheating.
●Do not get water or foreign materials in either the air intake/discharge vents as this
may cause a short circuit and damage the hybrid battery (traction battery).
●Do not carry large amounts of water such as water cooler bottles in the vehicle. If
water spills onto the hybrid battery (tract ion battery), the battery may be damaged.
Have the vehicle inspected by your Lexus dealer.

952. Instrument cluster
2
Instrument cluster
RX450h_U_OM0E013U
●Drive mode indicators
Except F SPORT modelsIntuitive parking assist
indicator (
P. 339)
(Canada)
Parking brake indicator
( P. 245)
“BSM” indicator ( P. 363)
*1Brake hold standby
indicator ( P. 249)
“RCTA” indicator
( P. 363)
*1Brake hold operated
indicator ( P. 249)
*2, 3
BSM outside rear view
mirror indicators ( P. 363) EV indicator (
P. 78)
*1, 4
Slip indicator ( P. 383)*6
Security indicator
( P. 85, 87)
*1, 5VSC OFF indicator
( P. 384) “READY” indicator
(
P. 232)
*1, 5
(if equipped)
PCS warning light
( P. 283)*7
Low outside temperature
indicator ( P. 97)
(U.S.A.)
Parking brake indicator
( P. 245, 246)*1, 6“AIR BAG ON/OFF”
indicator ( P. 51)
Eco drive mode indicator
( P. 377) “SPORT” indicator
(
P. 377)
EV drive mode indicator
( P. 237)

1333-1. Key information
3
Operation of each component
RX450h_U_OM0E013U
To take out the mechanical key, push
the release button and take the key out.
The mechanical key can only be
inserted in one direction, as the key only
has grooves on one side. If the key can-
not be inserted in a lock cylinder, turn it
over and re-attempt to insert it.
After using the mechanical key, store it
in the electronic key. Carry the mechan-
ical key together with the electronic key.
If the electronic key battery is depleted
or the entry function does not operate
properly, you will need the mechanical
key. ( P. 564)
■Panic mode
■When required to leave the vehicle’s key with a parking attendant
Lock the glove box as circumstances demand. ( P. 422)
Remove the mechanical key for your own use and provide the attendant with the elec-
tronic key only.
■If you lose your mechanical keys
New genuine mechanical keys can be made by your Lexus dealer using another
mechanical key and the key number stamped on your key number plate. Keep the plate
in a safe place such as your wallet, not in the vehicle.
■When riding in an aircraft
When bringing an electronic key onto an aircraft, make sure you do not press any but-
tons on the electronic key while inside the airc raft cabin. If you are carrying an electronic
key in your bag, etc., ensure that the butt ons are not likely to be pressed accidentally.
Pressing a button may cause the electronic key to emit radio waves that could interfere
with the operation of the aircraft.
Using the mechanical key
When is pressed for longer than about
one second, an alarm will sound intermittently
and the vehicle lights will flash to deter any per-
son from trying to break into or damage your
vehicle.
To stop the alarm, press any button on the elec-
tronic key.