Page 4 of 563

TABLE OF CONTENTSIndex
ES350_U
2
1-1. Key informationKeys ...................................................... 24
1-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start .......................... 26
Wireless remote control ............. 38
Doors.................................................... 40
Trunk..................................................... 44
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats .......................................... 48
Driving position memory (driver’s seat) ................................. 49
Seat position memory (front passenger’s seat) ............. 53
Head restraints................................. 55
Seat belts ............................................ 57
Steering wheel.................................. 63
Anti-glare inside rear view mirror ................................................ 64
Outside rear view mirrors ........... 66 1-4. Opening and closing the
windows and moon roof
Power windows................................ 68
Moon roof ............................................ 71
1-5. Refueling Opening the fuel tank cap........... 76
1-6. Theft deterrent system Engine immobilizer system ......... 79
Alarm..................................................... 81
1-7. Safety information Correct driving posture ............... 84
SRS airbags ....................................... 86
Front passenger occupant classification system .................... 97
Child restraint systems ............... 102
Installing child restraints ............. 106
2-1. Driving procedures Driving the vehicle ......................... 118
Engine (ignition) switch .............. 126
Automatic Transmission ............ 130
Turn signal lever............................. 133
Parking brake ................................. 134
Horn.................................................... 135
1Before driving
2When driving
Page 7 of 563

1
2
3
4
5
6
7
ES350_U
5
4-1. Maintenance and careCleaning and protecting the vehicle exterior................... 362
Cleaning and protecting the vehicle interior .................... 365
4-2. Maintenance Maintenance requirements .... 368
General maintenance ................ 370
Emission inspection and maintenance (I/M)
programs ...................................... 373
4-3. Do-it-yourself maintenance Do-it-yourself service precautions .................................. 374
Hood.................................................. 378
Positioning a floor jack............... 379
Engine compartment................... 381
Tires ................................................... 394
Tire inflation pressure................ 403
Wheels.............................................. 407
Air conditioning filter................. 409
Electronic key battery ................... 411
Checking and replacing fuses ................................................. 413
Headlight aim (vehicles with discharge headlights) .............. 422
Light bulbs ....................................... 424 5-1. Essential information
Emergency flashers .................... 434
If your vehicle needs to be towed ............................................. 435
If you think something is wrong .............................................. 441
Fuel pump shut off system ........ 442
Event data recorder.................... 443
5-2. Steps to take in an emergency If a warning light turns on or a warning buzzer
sounds... ........................................ 445
If a warning message is displayed....................................... 455
If you have a flat tire..................... 467
If the engine will not start .......... 476
If the shift lever cannot be shifted from P .............................. 478
If you lose your keys .................... 479
If the electronic key does not operate properly .............. 480
If the vehicle battery is discharged .................................. 483
If your vehicle overheats ........... 486
If the vehicle becomes stuck............................................... 489
If your vehicle has to be stopped in an emergency ...... 490
4Maintenance and care5When trouble arises
Page 8 of 563
TABLE OF CONTENTSIndex
ES350_U
6
6-1. SpecificationsMaintenance data (fuel, oil level, etc.)..................... 492
Fuel information ........................... 502
Tire information............................ 505
6-2. Customization Customizable features................ 517
6-3. Initialization Items to initialize ........................... 525
Reporting safety defects for U.S. owners.......................... 528
Seat belt instructions for Canadian owners
(in French) .................................... 529
SRS airbag instructions for Canadian owners
(in French) ..................................... 531 Abbreviation list ................................... 542
Alphabetical index .............................. 544
What to do if... ...................................... 558
6Vehicle specifications
7For owners
Index
Page 11 of 563
ES350_U
9
Tires
●Rotation
● Replacement
● Inflation pressure
P. 394
P. 467
P. 499
Tail lights P. 147
Side marker lights P. 147
Trunk P. 44
Rear window defogger P. 215
Doors P. 40
Fuel filler door P. 76
Turn signal lights P. 133
Page 19 of 563
ES350_U
17
C
Rear sunshade
switch
∗ P. 335
Intuitive parking assist
switch
∗ *2P. 171
Instrument panel light
control
P. 137
∗: If equipped
*2: Refer to “Navigation System Owner's Manual”.
Outside rear view mirror switch P. 66
Auxiliary box P. 323
Type A
Type B
Trunk opener P. 44
Fuel filler door opener P. 76
Rear sunshade
switch
∗ P. 335
Instrument panel light
control
P. 137
Outside rear view mirror switch P. 66
Auxiliary box P. 323
Trunk opener P. 44
Fuel filler door opener P. 76
VSC off switch P. 178
VSC off switch P. 178
Page 20 of 563
ES350_U
18
For your information
Main Owner’s Manual
Please note that this manual applies to all models and explains all equipment, includ-
ing options. Therefore, you may find some explanations for equipment not installed
on your vehicle.
All specifications provided in this manual are current at the time of printing. How-
ever, because of the Lexus policy of continual product improvement, we reserve the
right to make changes at any time without notice.
Depending on specifications, the vehicle shown in the illustration may differ from
your vehicle in terms of color and equipment.
Noise from under vehicle after turning off the engine
Approximately five hours after the engine is turned off, you may hear sound coming
from under the vehicle for several minutes. This is the sound of a fuel evaporation
leakage check and, it does not indicate a malfunction.
Page 21 of 563

ES350_U
19
Accessories, spare parts and modification of your Lexus
A wide variety of non-genuine spare parts and accessories for Lexus vehicles are
currently available in the market. You should know that Toyota does not warrant
these products and is not responsible for their performance, repair, or replacement,
or for any damage they may cause to, or adverse effect they may have on, your
Lexus vehicle.
This vehicle should not be modified with non-genuine Lexus products. Modification
with non-genuine Lexus products could affect its performance, safety or durability,
and may even violate governmental regulations. In addition, damage or perfor-
mance problems resulting from the modification may not be covered under war-
ranty.
Installation of a mobile two-way radio system
As the installation of a mobile two-way radio system in your vehicle could affect
electronic systems such as the multiport fuel injection system/sequential multiport
fuel injection system, cruise control system, anti-lock brake system, SRS airbag sys-
tem and seat belt pretensioner system, be sure to check with your Lexus dealer for
precautionary measures or special instructions regarding installation.
Page 25 of 563

Before driving1
23
ES350_U
1-1. Key informationKeys ............................................... 24
1-2. Opening, closing and locking the doors
and trunk
Smart access system with push-button start .................... 26
Wireless remote control ........ 38
Doors ........................................... 40
Trunk ............................................. 44
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats .................................. 48
Driving position memory (driver’s seat) ........................... 49
Seat position memory (front passenger’s seat) ........ 53
Head restraints .......................... 55
Seat belts ..................................... 57
Steering wheel........................... 63
Anti-glare inside rear view mirror ......................................... 64
Outside rear view mirrors ...... 66 1-4. Opening and closing the
windows and moon roof
Power windows .......................... 68
Moon roof .................................... 71
1-5. Refueling Opening the fuel tank cap ...... 76
1-6. Theft deterrent system Engine immobilizer system.... 79
Alarm............................................. 81
1-7. Safety information Correct driving posture ......... 84
SRS airbags ................................ 86
Front passenger occupant classification system.............. 97
Child restraint systems ......... 102
Installing child restraints....... 106