
1, 2, 3 ...
4-ETS see ETS/4-ETS                                          
4MATIC
see All-wheel drive (4MATIC)                    
A
ABS (Antilock Brake System)  ............. 62
Indicator lamp ................................ 305
Messages in the multifunction
display  ................................... 288, 289
Accessory weight  .............................. 249
Accidents  ........................................... 112
Air bags  ........................................... 37
Emergency calls (Tele Aid)  .............208
NECK-PRO active front head
restraints   ........................................ 54
Active Bi-Xenon headlamps
see Headlamps                                         
Adaptive Brake  .................................... 64
Adaptive Highbeam Assist  ............... 100
Switching on or off ......................... 142
AdBlue ®
 ...................................... 333, 364
Refilling   ......................................... 334
Additives  
Engine oil  ....................................... 362
Gasoline ......................................... 364
Address change  ................................... 21
Advanced Tire Pressure
Monitoring System (Advanced
TPMS)  ................................................. 233
Messages in the multifunction
display  ........................................... 285
Air bags  ................................................ 37
Emergency call upon deployment  ..208
Front, driver and passenger  .............40
Front passenger front air bag off
indicator lamp (Canada
only)  ........................................ 46, 313
Front passenger front air bag off
indicator lamp (USA only)  ........43, 314
Knee bag .......................................... 40
Messages in the multifunction
display  ........................................... 276
OCS (Occupant Classification
System)  ........................................... 43
Pelvis ............................................... 42
Safety guidelines  ............................. 39
Side impact  ...................................... 41
Window curtain  ................................ 42
Air conditioning refrigerant and
lubricant  ............................................. 362
Air distribution  .................................. 189
Air filter  .............................................. 299
AIRMATIC  
Damping system  ............................ 163
Introduction  ................................... 163
Messages in the multifunction
display  ........................................... 292
Vehicle level control  ......................163
Air pressure
see Tire inflation pressure                        
Air pressure (tires)  ............................ 250
Air pump (electric)  ............................ 327
Air recirculation mode  ...................... 190
Air volume  .......................................... 189
Alarm system see Anti-theft systems                              
Alignment bolt (vehicle tool kit)  ...... 326
All-wheel drive (4MATIC)  .................. 161
Alternator  
Messages in the multifunction
display  ................................... 284, 297
Alternator (Technical data)
see Vehicle specification                          
AMG adaptive sport suspension
system (E 63 AMG)  ............................ 164
AMG menu  ......................................... 131
Anticorrosion/antifreeze  .................. 365
Antilock Brake System see ABS                                                     
Anti-theft systems  ............................... 71
Anti-theft alarm system  ...................72
Immobilizer  ...................................... 71
Aquaplaning
see Hydroplaning                                      
Armrest, front  
Storage compartment  ....................202
Armrest, rear  
Storage compartment  ....................202
Ashtrays  ............................................. 206
Aspect ratio (tires)  ............................ 250
Assistance menu  ............................... 1374Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 4 

ATTENTION ASSIST ........................... 178
Messages in the multifunction
display  ........................................... 292
Switching on or off ......................... 138
Audio menu  ........................................ 134
Auto-dimming rear view mirrors  ........ 95
Automatic central locking  .......... 80, 144
Automatic climate control see Climate control system                      
Automatic headlamp mode  ................ 98
Automatic interior lighting control  .. 103
Automatic locking when driving  ...... 144
Automatic shift program  .................. 120
Automatic transmission  ................... 114
Automatic shift program  ................120
Gear range indicator  ......................120
Gear ranges  ................................... 120
Gear selector lever  ........................115
Hill-start assist system  ..................160
Kickdown  ....................................... 119
Kickdown (manual shift program)  ..124
Manual shift program ..................... 122
One-touch gearshifting  ..................121
Program mode indicator  ................121
Program mode selector dial
(E 63 AMG)  ............................ 121, 123
Program mode selector switch
(automatic shift program)  ..............120
Shifting procedure  .........................118
Steering wheel gearshift control  ....122
Transmission position indicator  .....118
Transmission positions  ..................118
AUX socket  ........................................ 201
Axle oils  .............................................. 360
B
BabySmart™  
Air bag deactivation system  .............46
Self-test  ........................................... 47
Backrest
see Seats                                                  
Backup lamps  
Messages in the multifunction
display  ........................................... 300
Bar (air pressure unit)  ....................... 250
BAS (Brake Assist System)  ................. 63
BAS PLUS (Brake Assist System
PLUS)  .................................................... 63
Batteries, SmartKey  
Checking condition  ..........................79
Replacing  ....................................... 317
Battery, Vehicle  ................................. 336
Charging  ........................................ 337
Jump starting  ................................. 338
Messages in the multifunction
display  ................................... 284, 297
Bead (tire)  .......................................... 250
Beverage holders see Cup holders                                        
Bleeding the fuel system (diesel
engine)  ............................................... 333
Blind Spot Assist  ............................... 175
Messages in the multifunction
display  ........................................... 281
Switching on or off ......................... 138
BlueTEC  
AdBlue ®
 tank  ................................. 333
Brake Assist System
see BAS                                                     
Brake Assist System PLUS
see BAS PLUS                                           
Brake fluid  
Checking level  ............................... 227
Messages in the multifunction
display  ........................................... 289
Brake lamps  
Cleaning lenses  ............................. 262
Brake pads  
Messages in the multifunction
display  ........................................... 287
Brakes  ................................................ 254
Ceramic brake system  ...................256
High-performance brake system  ....256
Parking brake  ................................ 113
Warning lamp ................................. 305
Break-in period  .................................. 220
Bug cover (Radiator)  ......................... 224
Bulbs see Replacing bulbs                                  Index5212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 5 

C
CAC (Customer Assistance Center)  ... 23
California retail buyers and
lessees, important notice for  ............. 21
Calls (phone)  ...................................... 135
Can holders see Cup holders                                        
Capacities and recommended
fuel/lubricants  .................................. 359
Cargo tie-down rings  ......................... 199
Carpets, cleaning  .............................. 266
Center console  ..................................... 32
Central locking  
Automatic  ................................ 80, 144
KEYLESS-GO  .................................... 77
Locking/unlocking from inside  ........81
SmartKey  ......................................... 76
Central locking/unlocking switch  ..... 81
Ceramic brake system  ...................... 256
Certification label  .............................. 346
Children in the vehicle  
Air bags  ........................................... 37
BabySmart™ air bag deactivation
system  ............................................. 46
Child safety locks (rear doors)  .........60
Child seat anchors – LATCH-type
(ISOFIX)  ........................................... 59
Indicator lamp, front passenger
front air bag off (Canada only)  .........46
Indicator lamp, front passenger
front air bag off (USA only)  ..............43
Infant and child restraint systems .... 56
ISOFIX (Child seat anchors –
LATCH-type) ..................................... 59
OCS (Occupant Classification
System)  ........................................... 43
Override switch  ................................ 60
Safety notes ..................................... 56
Tether anchorage points  ..................58
Top tether  ........................................ 58
Child safety
see Children in the vehicle                        
Child seat anchors – LATCH-type
(ISOFIX) see Children in the vehicle                        
Chrome-plated exhaust tip,
cleaning  .............................................. 266Cigarette lighter ................................ 206
Climate control see Climate control system                      
Climate control system  .................... 180
Air conditioning  ............................. 185
Air conditioning refrigerant  ............362
Air distribution  ............................... 189
Air recirculation mode  ...................190
Air volume  ..................................... 189
Automatic mode  ............................ 186
Deactivating system  ......................185
Front defroster  .............................. 189
Maximum cooling MAX COOL  ........190
Residual heat and ventilation  .........191
Temperature  .................................. 186
Cockpit  ................................................. 27
Cold tire inflation pressure  .............. 250
Collapsible wheel chock  ................... 270
COMAND system see separate COMAND system
operating instructions                               
Combination switch  .......................... 100
Compass  ............................................ 216
Control system  .................................. 126
Multifunction display  .....................128
Multifunction steering wheel  .........126
Resetting to factory settings  ..........139
Control system menus  ...................... 129
AMG ............................................... 131
Assistance  ..................................... 137
Audio  ............................................. 134
Navi  ............................................... 134
Service ........................................... 138
Settings  ......................................... 139
Telephone  ...................................... 135
Trip  ................................................ 129
Control system submenus  
Convenience  .................................. 145
Instrument cluster  .........................140
Lighting  .......................................... 141
Vehicle  ........................................... 144
Convenience submenu  
Easy-entry/exit feature .................. 145
Seat belt adjustment function  .......145
Coolant  
Anticorrosion/antifreeze  ...............365
Capacities  ...................................... 361
Checking level  ............................... 2266Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 6 

Program mode selector dial (E 63 AMG) 
Automatic shift program  ........121, 123
Program mode selector switch  
Automatic shift program  ................120
Proximity key
see Key, SmartKey                                    
PSI (air pressure unit)  ....................... 251
R
RACE START (E 63 AMG)  ................... 159
RACETIMER  ........................................ 132
Radar sensors  
Messages in the multifunction
display  ........................................... 282
Switching on or off ......................... 144
Radiator  ..................................... 224, 252
Radio  
Selecting stations  ..........................134
Radio transmitters  ............................ 257
Rain sensor see Intermittent wiping                             
Rear axle oil  ....................................... 360
Rear center console ashtray see Ashtrays                                             
Rear center seat belt  
Unblocking ....................................... 51
Rear doors  
Child safety locks  ............................ 60
Rear door window  
Override switch  ................................ 60
Rear fog lamp
see Fog lamps                                           
Rear lamps
see Tail lamps                                           
Rear seat head restraints
see Head restraints                                   
Rear view camera  .............................. 171
Cleaning the camera lens  ..............263
Rear window defroster  ..................... 191
Recommended tire inflation
pressure  ..................................... 229, 251
Refilling  
AdBlue ®
 ......................................... 334
Refrigerant, air conditioning  ............ 362
Refueling  ............................................ 220
Regular checks  .................................. 222
Reminder, Seat belt
see Seat belts, Telltale                              
Remote control
see Key, SmartKey                                    
Remote door lock (Tele Aid)  ............. 212
Remote door unlock (Tele Aid)  ......... 211
Replacing  
Key  .................................................. 80
Replacing bulbs  ................................. 318
Reporting safety defects  .................... 23
Research Octane Number see RON                                                    
Reserve fuel  
Messages in the multifunction
display  ........................................... 298
Warning lamp ................................. 310
Restraint systems
see Occupant safety                                 
Retaining hook  .................................. 199
Rims  ........................................... 251, 353
Roadside Assistance  ................... 21, 210
Roller sunblinds  ................................. 194
RON (Research Octane Number)  ..... 363
Roof rack  ............................................ 198
Rubber parts, cleaning  ...................... 265
Run-flat tires see MOExtended tires                               
S
Safety  
Driving safety systems  .....................61
Occupant safety ............................... 36
Reporting defects  ............................ 23
Safety belts
see Seat belts                                           
Seat belt force limiter  ......................... 52
Seat belts  ............................................. 48
Adjustment function  ........................51
Automatic comfort-fit feature  ..........53
Children in the vehicle  .....................56
Cleaning ......................................... 266
Fastening  ......................................... 50
Height adjustment  ...........................51
Proper use of  ................................... 49
Rear center seat  .............................. 51
Safety guidelines  ............................. 39
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T
Tachometer  .................................. 28, 126
Overspeed range  ........................... 126
Tail lamps  
Cleaning lenses  ............................. 262
Tar stains  ........................................... 261
Technical data  
Air conditioning refrigerant  ............362
Brake fluid  ..................................... 362
Capacities fuels, coolants,
lubricants etc.  ................................ 359
Coolant  .......................................... 365
Engine oil additives  ........................362
Engine oils  ..................................... 361
Fuel requirements .......................... 363
Gasoline additives .......................... 364
Identification labels  .......................346
Premium unleaded gasoline  ...........362
Rims and tires  ................................ 353
Spare wheel  ................................... 358
Vehicle specification E 350 ............ 348
Vehicle specification
E 350 4MATIC ................................ 349
Vehicle specification
E 350 BlueTEC  ............................... 348
Vehicle specification E 550 ............ 350
Vehicle specification
E 550 4MATIC ................................ 351
Vehicle specification E 63 AMG  .....352
Washer and headlamp cleaning
system  ................................... 361, 367
Technical data (dimensions)
see Vehicle specification                          
Technical data (electrical system)
see Vehicle specification                          
Technical data (engine)
see Vehicle specification                          
Technical data (weights)
see Vehicle specification                          
Tele Aid  ............................................... 207
Emergency calls  ............................. 208
Information button  .........................210
Initiating an emergency call
manually  ........................................ 209
Messages in the multifunction
display  ........................................... 290
Remote door lock  .......................... 212Remote door unlock  ......................211
Roadside Assistance button  ..........210
Search & Send  ............................... 211
SOS button  .................................... 209
Stolen Vehicle Recovery Services  ..212
System self-test  ............................. 208
Telephone  ............................................. 30
Answering/ending a call  ................136
Hands-free microphone  ...................33
Menu  ............................................. 135
Operation ....................................... 135
Phone book .................................... 136
Redialing  ........................................ 137
Temperature  
Coolant  .......................................... 125
Interior temperature  ......................186
Outside  .......................................... 126
Tether anchorage points
see Children in the vehicle                        
Through-loading feature  ................... 198
Tie-down rings  ................................... 199
Tightening torque  
Wheels  ........................................... 328
TIN (Tire Identification Number)  ...... 251
Tire and Loading Information
placard  ............................................... 237
Tire and loading terminology  ........... 249
TIREFIT  ............................................... 329
Tire Identification Number see TIN                                                      
Tire inflation pressure  
Checking ........................................ 231
Important notes on  ........................230
Label on the inside of fuel filler
flap  ................................................ 230
Placard on driver’s door B-pillar  .....237
Tire labeling  ....................................... 245
Tire load rating  .................................. 250
Tire ply composition and material
used  .................................................... 251
Tire pressure loss warning system  . 232
Tire repair kit see TIREFIT                                               
Tires  ........................................... 228, 353
Advanced Tire Pressure
Monitoring System (Advanced
TPMS)  ............................................ 233Index17212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 17 

Rhode Island, and Vermont Emission
Control System Warranty
R State Warranty Enforcement Laws (Lemon
Laws)
Important notice for California retail 
buyers and lessees of Mercedes-Benz 
automobiles
Under California law you may be entitled to a
replacement of your vehicle or a refund of the
purchase price or lease price, if after a
reasonable number of repair attempts
Mercedes-Benz USA, LLC and/or its
authorized repair or service facilities fail to fix
one or more substantial defects or
malfunctions in the vehicle that are covered
by its express warranty. During the period of
18 months from original delivery of the
vehicle or the accumulation of 18  000 miles
(approximately 29  000 km) on the odometer
of the vehicle, whichever occurs first, a
reasonable number of repair attempts is
presumed for a retail buyer or lessee if one or
more of the following occurs:
(1)the same substantial defect or
malfunction results in a condition that is
likely to cause death or serious bodily
injury if the vehicle is driven, that defect
or malfunction has been subject to repair
two or more times, and you have directly
notified Mercedes-Benz USA, LLC in
writing of the need for its repair,(2)the same substantial defect or
malfunction of a less serious nature than
category (1) has been subject to repair
four or more times and you have directly
notified us in writing of the need for its
repair, or(3)the vehicle is out of service by reason of
repair of the same or different substantial
defects or malfunctions for a cumulative
total of more than 30 calendar days.
Written notification should not be sent to a
dealer, it should be addressed to
Mercedes-Benz USA, LLC
Customer Assistance Center
One Mercedes Drive
Montvale, NJ 07645-0350
Maintenance
The Maintenance Booklet describes all the
necessary maintenance work which should
be performed at regular intervals.
Always have the Maintenance Booklet with
you when you take the vehicle to an
authorized Mercedes-Benz Center for
service. The service advisor will record each
service in the booklet for you.
Roadside Assistance
The Mercedes-Benz Roadside Assistance
Program provides factory-trained technical
help in the event of a breakdown. Calls to the
toll-free Roadside Assistance number
1-800-FOR-MERCedes (1-800-367-6372) 
(in the USA) 1-800-387-0100 (in Canada)
will be answered by Mercedes-Benz
Customer Assistance Representatives
24 hours a day, 365 days a year.
For additional information refer to the
Mercedes-Benz Roadside Assistance
Program brochure (in the USA) or the
Roadside Assistance section of the Service
and Warranty Information Booklet (in
Canada) in your vehicle literature portfolio.
Change of address or ownership
If you change your address, be sure to send
in the “Change of Address Notice” found in
the Service and Warranty Information
Booklet, or simply call the Mercedes-Benz
Customer Assistance Center (in the USA) at
1-800-FOR-MERCedes (1-800-367-6372), or
Customer Service (in Canada) at
1-800-387-0100. This will assist us in
Introduction21212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 21Z 

The ETDs for the rear outer seats will activate
with or without the respective seat belts
fastened.
In an impact, the ETDs remove slack from the
seat belts in such a way that the seat belts fit
more snugly against the body. Seat belt force
limiters, when activated, are employed to
help reduce the peak force exerted by the
seat belts on occupants during a crash.
i The ETDs do not correct an incorrect seat
position or incorrectly worn seat belts.
The ETDs do not pull occupants back
toward the seat backrest.GWarning!
Pyrotechnic ETDs that were activated must be
replaced.
For your safety, when disposing of the
pyrotechnic ETDs always follow our safety
instructions. These are available at any
authorized Mercedes-Benz Center.
The PRE-SAFE ®
 system has electrically
operated reversible pre-tensioners that do
not require replacement after activation.
Automatic comfort-fit feature seat belt
An automatic comfort-fit feature for the front
seats reduces the retracting force of the seat
belts when they are in normal use.
Preventive occupant safety (PRE-
SAFE ®
)
GWarning!
The PRE-SAFE ®
 system is intended to reduce
the effects of an accident on vehicle
occupants who are wearing their seat belt
properly. Despite your vehicle being equipped
with the PRE-SAFE ®
 system, the possibility of
personal injuries occurring as a result of an
accident cannot be eliminated. Therefore,
always drive carefully and adjust your driving
to the prevailing road, weather, and traffic
conditions.
The PRE-SAFE ®
 system takes preventive
measures to better protect the occupants
from the possibility of personal injuries in the
following hazardous situations:
R emergency braking situations, e.g. if the
Brake Assist System (BAS) ( Y page 63) is
activated
or when
vehicles with DISTRONIC PLUS:
the BAS PLUS ( Y page 63) or the PRE-
SAFE ®
 Brake ( Y page 69) is strongly
engaging
R when the radar sensors recognize the
immediate risk of collision in certain
situations (vehicles with DISTRONIC PLUS)
R critical dynamic driving situations, e.g.
when the vehicle has been caused to
understeer or oversteer because it has
exceeded its physical limitations or in case
of evasive steering maneuvers at speeds
above approximately 85 mph (140 km/h)
The PRE-SAFE ®
 system takes the following
measures when it is activated:
R The front seat belts are pre-tensioned
automatically.
R If the front passenger seat is in an
unfavorable position, the seat will be
adjusted to a position that seeks to better
protect the occupant.
R The system increases the air pressure in
the air pockets (on the sides of the seat
cushion and backrest) of the drive-dynamic
multicontour front seats.
R If the vehicle is in a critical dynamic driving
situation, the door windows and the tilt/
sliding sunroof or panorama roof with tilt/
sliding panel also closes, except for a
minimal gap that remains open.
If the closing procedure of any of these
elements is blocked, it will stop and open
slightly.
Once the hazardous situation no longer exists
and an accident has been avoided, the PRE-
SAFE ®
 system loosens the seat belt pre-Occupant safety53Safety and security212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 53Z 

iCanada only:
This device complies with RSS-210 of
Industry Canada. Operation is subject to
the following two conditions:
1. This device may not cause interference,
and
2. this device must accept any interference received, including
interference that may cause undesired
operation of the device.
Any unauthorized modification to this
device could void the user’s authority to
operate the equipment.
Important notes on using KEYLESS-GO 
R You can also use the SmartKey with
KEYLESS-GO like a normal SmartKey
( Y  page 76).
R You can combine KEYLESS-GO functions
with normal SmartKey functions (e.g.
unlocking with KEYLESS-GO and locking
with button  &).
R Always carry the SmartKey with you.
R Never store the SmartKey together with
- electronic items such as a mobile phone
or another SmartKey
- metallic objects such as coins or metal
foil
Doing so could impair the function of the
KEYLESS-GO system.
R To lock or unlock the vehicle, the SmartKey
must be located outside the vehicle within
approximately 3 ft (1 m) of a door or the
trunk.
R When the vehicle has been parked for more
than 72 hours, the KEYLESS-GO function is
deactivated. Pull an outside door handle
and switch on the ignition once to activate
the KEYLESS-GO function.
R If the SmartKey is positioned farther away
from the vehicle, the system may no longer
recognize the SmartKey. The vehicle
cannot be locked or the engine started via
the KEYLESS-GO system.
R If the SmartKey is removed from the vehicle
(e.g. if a passenger exits the vehicle with
the SmartKey)
- when pressing the KEYLESS-GO start/
stop button or trying to lock the vehicle
with the outside door handle the
message  Key Not Detected  appears in
the multifunction display
- with the engine running, the red message
Key Not Detected  appears in the
multifunction display while driving off
Find the SmartKey or change its present
location immediately (e.g. place it on the
front passenger seat or insert it in shirt
pocket).
R If you have started the engine with the
KEYLESS-GO start/stop button, you can
turn it off again by
- pressing the KEYLESS-GO start/stop
button
- inserting the SmartKey into the starter
switch when the vehicle is at a standstill
and the automatic transmission is in park
position  P
R The vehicle could be inadvertently
unlocked if the SmartKey is within 3 ft (1 m)
of the vehicle and
- an outside door handle is splashed with
water
or
- you attempt to clean an outside door
handle
R Remember that the engine can be started
by anyone with a SmartKey that is left
inside the vehicle.
Possibility 1  (One SmartKey in the vehicle,
one SmartKey outside the vehicle):
If you leave the SmartKey behind when
exiting and locking the vehicle, no message
appears in the multifunction display.78Locking and unlockingControls in detail
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