
TABLE OF CONTENTSIndex
ES350_U_(L/O_0708)
2
1-1. Key information ........................... 20Keys ...................................................... 20
1-2. Opening, closing and locking the doors and trunk .................. 22
Smart access system with push-button start .......................... 22
Wireless remote control .............. 34
Doors.................................................... 37
Trunk...................................................... 41
1-3. Adjustable components (seats, mirrors,
steering wheel) .......................... 43
Front seats .......................................... 43
Driving position memory ............. 44
Seat position memory ................... 47
Head restraints................................. 49
Seat belts ........................................... 50
Steering wheel.................................. 56
Anti-glare inside rear view mirror ................................................ 57
Outside rear view mirrors .......... 58
1-4. Opening and closing the windows and moon roof .......... 60
Power windows................................ 60
Moon roof .......................................... 63 1-5. Refueling ........................................ 67
Opening the fuel tank cap........... 67
1-6. Theft deterrent system............... 70 Engine immobilizer system ......... 70
Alarm.................................................... 72
Theft prevention labels (for USA) ......................................... 74
1-7. Safety information ....................... 75 Correct driving posture ............... 75
SRS airbags ....................................... 77
Front passenger occupant classification system ................... 88
Child restraint systems ................. 93
Installing child restraints ............... 96
2-1. Driving procedures................... 106 Driving the vehicle ........................ 106
Engine (ignition) switch ................ 114
Automatic Transmission .............. 117
Turn signal lever............................. 120
Parking brake ................................... 121
2-2. Instrument cluster ..................... 122 Gauges and meters ..................... 122
Indicators and warning lights ... 124
Multi-information display........... 128
1Before driving
2When driving

1
2
3
4
5
6
7
ES350_U_(L/O_0708)
5
5-1. Essential information .............. 352If your vehicle needs to be towed ....................................... 352
If you think something is wrong ........................................ 358
Fuel pump shut off system ........ 359
Event data recorder................... 360
5-2. Steps to take in an emergency .............................. 362
If a warning light turns on or a warning buzzer
sounds... ........................................ 362
If a warning message is displayed....................................... 373
If you have a flat tire.................... 384
If the engine will not start .......... 394
If the shift lever cannot be shifted from P .............................. 396
If you lose your keys .................... 397
If the electronic key does not operate properly .............. 398
If the vehicle battery is discharged .................................. 400
If your vehicle overheats .......... 403
If the vehicle becomes stuck............................................... 405 6-1. Specifications............................ 408
Maintenance data (fuel, oil level, etc.).................... 408
Fuel information............................. 418
Tire information ............................. 421
6-2. Customization .......................... 433 Customizable features .............. 433
6-3. Initialization ............................... 438 Items to initialize .......................... 438
Reporting safety defects for U.S. owners........................... 440
Abbreviation list .................................. 442
Alphabetical index.............................. 444
What to do if... ...................................... 454
5When trouble arises6Vehicle specifications
7For US owners
Index

12
Pictorial indexInstrument panel
Headlight switch Turn signal lever Fog light switch P. 132
P. 120
P. 135Gauges and meters P. 122
Multi-information display P. 128
Windshield wipers and
washer switch
P. 136
“ENGINE START STOP” switch P. 114
Trunk opener main switch P. 41
Glove box P. 250
Tilt and telescopic steering control switch P. 56
Parking brake pedal P. 121
Audio remote control switches P. 217
Hood lock release lever P. 298
Tire pressure warning system reset switch P. 318
Adaptive front lighting system cancel switch∗ P. 133
Tire pressure warning system select switch P. 319

ES350_U_(L/O_0708)
18
Symbols used throughout this manual
Cautions & Notices
Safety symbol
CAUTION
This is a warning against anything which may cause injury to people if the warning is
ignored. You are informed about what you must or must not do in order to reduce the
risk of injury to yourself and others.
NOTICE
This is a warning against anything which may cause damage to the vehicle or its
equipment if the warning is ignored. You are informed about what you must or must
not do in order to avoid or reduce the risk of damage to your Lexus and its equipment.
Throughout this manual, you will also see the symbol of a circle
with a slash through it. This means “Do not”, “Do not do this”, or
“Do not let this happen”.

30
1-2. Opening, closing and locking the doors and trunk
ES350_U_(L/O_0708)
■Alarms and warning indicators
A combination of exterior and interior alarms as well as warnings displayed on the
multi-information display are used to prevent theft of the vehicle and unforeseeable
accidents resulting from erroneous operation. Take appropriate measures in
response to any warning indications on the multi-information display. (→P. 3 7 3 )
The following table describes circumstances and correction procedures when only
alarms are sounded.
AlarmSituationCorrection procedure
Exterior alarm
sounds once for 2
seconds
Tried to lock the doors using
the entry function while the
electronic key is still inside
the passenger compartmentRetrieve the electronic
key from the passenger
compartment and lock
the doors again.
Closed the trunk while the
electronic key is still inside
the trunk and all doors are
lockedRetrieve the electronic
key from the trunk and
close the trunk lid.
Exterior alarm
sounds once for 60
seconds
Tried to exit the vehicle with
the electronic key and lock
the doors without first turning
the “ENGINE START STOP”
switch OFFTurn the “ENGINE
START STOP” switch
OFF and lock the doors
again.
Exterior alarm
sounds once for 10
secondsTried to lock the vehicle using
the entry function while a
door is openClose all of the doors
and lock the doors
again.
Exterior alarm
sounds once for 3
seconds and inte-
rior alarm sounds
continuously
When the “ENGINE START
STOP” switch is in ACCES-
SORY or IGNITION ON
mode, an attempt was made
to open the door and exit the
vehicle, and the shift lever
was not in P.
Shift the shift lever to P.

32
1-2. Opening, closing and locking the doors and trunk
ES350_U_(L/O_0708)
NOTICE:
This equipment has been tested and found to comply with the limits for a Class B
digital device, pursuant to Part 15 of the FCC Rules. These limits are designed to
provide reasonable protection against harmful interference in a residential installa-
tion. This equipment generates, uses and can radiate radio frequency energy and, if
not installed and used in accordance with the instructions, may cause harmful inter-
ference to radio communications. However, there is no guarantee that interference
will not occur in a particular installation. If this equipment does cause harmful inter-
ference to radio or television reception, which can be determined by turning the
equipment off and on, the user is encouraged to try to correct the interference by
one or more of the following measures:
●Reorient or relocate the receiving antenna.
●Increase the separation between the equipment and receiver.
●Connect the equipment into an outlet on a circuit different from that to which
the receiver is connected.
●Consult the dealer or an experienced radio/TV technician for help.
FCC WARNING:
Changes or modifications not expressly approved by the party responsible for
compliance could void the user's authority to operate the equipment.
For vehicles sold in Canada
N OT E :
Operation is subject to the following two conditions: (1) this device may not cause
interference, and (2) this device must accept any interference, including interfer-
ence that may cause undesired operation of the device.

35
1-2. Opening, closing and locking the doors and trunk
1
Before driving
ES350_U_(L/O_0708)
■When the electronic key battery is fully depleted
→P. 3 3 2
■Conditions affecting operation
→P. 2 6
■Customization that can be configured at Lexus dealer
Settings (e.g. trunk unlocking function) can be changed. (Customizable features
→P. 4 3 3 )
■Certification for wireless remote control
For vehicles sold in the USA
NOTE:
This device complies with Part 15 of the FCC Rules. Operation is subject to the fol-
lowing two conditions: (1) This device may not cause harmful interference, and (2)
this device must accept any interference received, including interference that may
cause undesired operation.
NOTICE:
This equipment has been tested and found to comply with the limits for a Class B
digital device, pursuant to Part 15 of the FCC Rules. These limits are designed to
provide reasonable protection against harmful interference in a residential installa-
tion. This equipment generates, uses and can radiate radio frequency energy and, if
not installed and used in accordance with the instructions, may cause harmful inter-
ference to radio communications. However, there is no guarantee that interference
will not occur in a particular installation. If this equipment does cause harmful inter-
ference to radio or television reception, which can be determined by turning the
equipment off and on, the user is encouraged to try to correct the interference by
one or more of the following measures:
●Reorient or relocate the receiving antenna.
●Increase the separation between the equipment and receiver.
●Connect the equipment into an outlet on a circuit different from that to which
the receiver is connected.
●Consult the dealer or an experienced radio/TV technician for help.
FCC WARNING:
Changes or modifications not expressly approved by the party responsible for
compliance could void the user's authority to operate the equipment.

78
1-7. Safety information
ES350_U_(L/O_0708)
Airbag system componentsYour vehicle is equipped with ADVANCED AIRBAGS designed based
on US motor vehicle safety standards (FMVSS208). The airbag system
controls airbag deployment power for the driver and front passenger. The
driver airbag system consists of the driver seat’s position sensor etc. The
front passenger’s airbag system consists of the front passenger occupant
classification sensor etc. Front passenger airbag
Curtain shield airbags
AIR BAG ON and AIR BAG
OFF indicator lights
Side airbags for the front pas-
sengers
Side and curtain shield airbag
sensors
Curtain shield airbag sensors
Side airbags for the rear out-
side passengers (if equipped)
SRS warning light
Driver airbag
Driver's seat position sensor
Knee airbags
Driver's seat belt buckle switch
Front passenger’s seat belt
buckle switch
Airbag sensor assembly
Occupant detection system
(ECU and sensors)
Front airbag sensors