The fuel economy of the GMC Canyon 2016 varies depending on the engine size. The 2.5L 4-cylinder engine has an EPA-estimated fuel economy of 20 mpg city/26 mpg highway, the 3.6L V6 engine has an EPA-estimated fuel economy of 18 mpg city/26 mpg highway, and the 2.8L Duramax turbo-diesel engine has an EPA-estimated fuel economy of 22 mpg city/31 mpg highway.