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GMC Sierra/Sierra Denali 2500 HD/3500 HD Owner Manual (GMNA-
Localizing-U.S./Canada-16504257) - 2023 - CRC - 5/18/22
330 Vehicle Care
Lift the cover to access the fuse block.
Caution
Spilling liquid on any electrical
component on the vehicle may damage
it. Always keep the covers on any
electrical component.
A fuse puller is available in the left
instrument panel end cap.
The vehicle may not be equipped with all of
the fuses, relays, and features shown.
Fuses Usage
1 High-beam left
2 High-beam right Fuses
Usage
3 Headlamp left
4 Headlamp right
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GMC Sierra/Sierra Denali 2500 HD/3500 HD Owner Manual (GMNA-
Localizing-U.S./Canada-16504257) - 2023 - CRC - 5/18/22
332 Vehicle Care
FusesUsage
65 Auxiliary underhood electrical center
66 Cooling fan motor left 67 Active fuel management 2
68 –
69 Starter Pinion (LD) / Starter Motor (HD Gas)
71 Cooling fan
72 Cooling fan right/lower
73 Trailer stop/turn lamp left
74 Trailer Interface Module 1
75 DEFC
76 Electric RNG BDS
78 Engine control module
79 Auxiliary battery
80 Cabin cooling pump 81 Trailer stop/turn lamp right Fuses
Usage
82 Trailer Interface Module 2
83 FTZM
84 Trailer brake 85 ENG
86 Engine control module 87 Injector B even
88 O2 B sensor
89 O2 A sensor
90 Injector A odd 91 Engine control module throttle control
92 Cool fan clutch/ Aeroshutter Relays
Usage
5 Headlamp
18 DC/AC inverter
23 Rear window defogger
35 Parking lamp
36 Run/Crank
43 –
59 A/C clutch
64 Starter Motor (LD & HD DSL)
70 Starter Pinion (LD) / Starter Motor (HD Gas)
77 Powertrain
Page 334 of 430
GMC Sierra/Sierra Denali 2500 HD/3500 HD Owner Manual (GMNA-
Localizing-U.S./Canada-16504257) - 2023 - CRC - 5/18/22
Vehicle Care 333
Instrument Panel Fuse Block (Left)
The left instrument panel fuse block access
door is on the driver side edge of the
instrument panel.
The vehicle may not be equipped with all of
the fuses, relays, and features shown.
Pull off the cover to access the fuse block.
A fuse puller is available on the left
instrument panel end cap.
The vehicle may not be equipped with all of
the fuses, relays, and features shown.Fuses Usage
F1 Rear Heated Seats Left/ Right
F3 –
F4 –
F5 Spare/MFEG –
Multifunction End Gate
F6 Heated and Ventilated Seats Left/Right
F8 –
F9 Passive Entry Passive Start/ Spare
F10 –
F11 –
F12 Passenger Power Seat
F13 Export Power Take Off/ Special Equipment Option 1
F14 –
F15 –
F16 AMP –Amplifier
F17 –
Page 335 of 430
GMC Sierra/Sierra Denali 2500 HD/3500 HD Owner Manual (GMNA-
Localizing-U.S./Canada-16504257) - 2023 - CRC - 5/18/22
334 Vehicle Care
FusesUsage
F18 –
F20 Endgate F22 Rear Sliding Window
F23 –
F24 –
F25 –
F26 –
F27 –
Circuit
Breakers Usage
CB1 – Relays
Usage
K1 Rear Sliding Window Open
K2 Rear sliding Window Close
K3 MFEG Major 1 –
Multifunction End Gate
Major 1
K4 MFEG Minor 1 –
Multifunction End Gate
Minor 1
K5 MFEG Minor 2 –
Multifunction End Gate
Minor 2
K6 MFEG Major 2 –
Multifunction End Gate
Major 2
K7 –
K8 –Instrument Panel Fuse Block
(Right)
The right instrument panel fuse block access
door is on the passenger side edge of the
instrument panel.
Pull off the cover to access the front of the
fuse block.
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GMC Sierra/Sierra Denali 2500 HD/3500 HD Owner Manual (GMNA-
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Vehicle Care 335
To access the back of the fuse block:
1. Push the tab at the top of fuseblock down.
2. Pull the top of the fuse block outward.
3. Reverse Steps 1–2 to reinstall.
Back
The vehicle may not be equipped with all of
the fuses, relays, and features shown.
Page 338 of 430

GMC Sierra/Sierra Denali 2500 HD/3500 HD Owner Manual (GMNA-
Localizing-U.S./Canada-16504257) - 2023 - CRC - 5/18/22
Vehicle Care 337
FusesUsage
F53 –
F54 Sunroof F55 Driver Power Seat
F56 DC DC TRANS 1 F57 DC DC TRANS 2
F58 Infotainment 2
Circuit
Breakers Usage
1 Accessory Power Outlet 2
2 Accessory Power Outlet 1/ Cigarette Lighter
3 –
4 –
Relays Usage
K1 Run/Crank
K2 Retained Accessory Power/ Accessory 1
K4 –
K5 –Wheels and Tires
Tires
Every new GM vehicle has high-quality
tires made by a leading tire
manufacturer. See the warranty manual
for information regarding the tire
warranty and where to get service. For
additional information refer to the tire
manufacturer.
{Warning
.Poorly maintained and improperly
used tires are dangerous.
.Overloading the tires can cause
overheating as a result of too
much flexing. There could be a
blowout and a serious crash. See
Vehicle Load Limits 0215.
.Underinflated tires pose the same
danger as overloaded tires. The
resulting crash could cause serious
injury. Check all tires frequently to
(Continued)
Warning (Continued)
maintain the recommended
pressure. Tire pressure should be
checked when the tires are cold.
.Overinflated tires are more likely
to be cut, punctured, or broken by
a sudden impact —such as when
hitting a pothole. Keep tires at the
recommended pressure.
.Worn or old tires can cause a
crash. If the tread is badly worn,
replace them.
.Replace any tires that have been
damaged by impacts with
potholes, curbs, etc.
.Improperly repaired tires can cause
a crash. Only your dealer or an
authorized tire service center
should repair, replace, dismount,
and mount the tires.
(Continued)
Page 410 of 430

GMC Sierra/Sierra Denali 2500 HD/3500 HD Owner Manual (GMNA-
Localizing-U.S./Canada-16504257) - 2023 - CRC - 5/9/22
OnStar 409
.Give OnStar Turn-by-Turn Navigation voice
commands.
.Obtain and customize the Wi-Fi hotspot
name or SSID and password, if equipped.
Press
Qto connect to an Advisor to:
.Verify account information or update
contact information.
.Get driving directions.
.Receive a Diagnostic check of the vehicle's
key operating systems.
.Receive Roadside Assistance.
.Manage Wi-Fi Settings, if equipped.
Press
>to get a priority connection to an
OnStar Advisor available 24/7 to:
.Get help for an emergency.
.Be a Good Samaritan or respond to an
AMBER Alert.
.Get assistance in severe weather or other
crisis situations and find evacuation
routes.
OnStar Services
Emergency
Emergency Services require an active safety
and security plan. With Automatic Crash
Response, built-in sensors can automatically
alert a specially trained OnStar Advisor who
is immediately connected in to the vehicle
to help.
Press
>for a priority connection to an
OnStar Advisor who can contact emergency
service providers, direct them to your exact
location, and relay important information.
With OnStar Crisis Assist, specially trained
Advisors are available 24 hours a day, 7 days
a week, to provide a central point of
contact, assistance, and information during a
crisis.
With Roadside Assistance, Advisors can
locate a nearby service provider to help with
a flat tire, a battery jump, or an empty
gas tank.
Security
If equipped, OnStar provides these services:
.With Stolen Vehicle Assistance, OnStar
Advisors can use GPS to pinpoint the
vehicle and help authorities quickly
recover it.
.With Remote Ignition Block, if equipped,
OnStar can block the vehicle from being
restarted.
.With Stolen Vehicle Slowdown,
if equipped, OnStar can work with law
enforcement to gradually slow the
vehicle down.
Theft Alarm Notification
If equipped, if the doors are locked and the
vehicle alarm sounds, a notification by text,
e-mail, or phone call will be sent. If the
vehicle is stolen, an OnStar Advisor can work
with authorities to recover the vehicle.