2022 LEXUS RX350 roof

2TABLE OF CONTENTS
For your information ......................................6
Reading this manual .................................... 10
How to search ................................................. 11
Pictorial index ................................................. 12
1-1. For safe use Before driving .................................... 24
For safe driving.................................. 25
Seat belts ............................................. 26
SRS airbags ....................................... 30
Front passenger occupant classifi- cation system ................................. 39
Exhaust gas precautions .............. 44
1-2. Child safety Riding with children........................ 45
Child restraint systems ................. 45
1-3. Lexus Enform Lexus Enform Safety Connect .. 60
1-4. Theft deterrent system Engine immobili zer system .........66
Alarm.................................................... 67
2-1. Instrument cluster Warning lights and indicators .... 70
Gauges and meters ....................... 75
Multi-information display............. 79
Head-up display .............................. 86
Fuel consumption information ... 903-1. Key information
Keys ....................................................... 94
3-2. Opening, closing and locking the doors
Side doors ........................................... 97
Power back door ........................... 101
Smart access system with push-but- ton start ............................................ 113
3-3. Adjusting the seats Front seats.......................................... 117
Rear seats.......................................... 118
Driving position memory ............ 129
Head restraints ............................... 132
3-4. Adjusting the steering wheel and mirrors
Steering wheel ............................... 135
Inside rear view mirror ............... 136
Outside rear view mirrors.......... 137
3-5. Opening, closing the windows and moon roof
Power windows ............................. 140
Moon roof ......................................... 142
Panoramic moon roof ................. 145
4-1. Before driving Driving the vehicle........................ 150
Cargo and luggage...................... 155
Vehicle load limits......................... 158
Trailer towing (vehicles without towing package)......................... 159
1For safety and security
2Vehicle status information and
indicators
3Before driving
4Driving

9
are, this may cause an accident such as
fire. Be sure to have the systems of the
SRS airbag and seat belt pretensioner
removed and disposed of by a qualified
service shop or by your Lexus dealer
before you scrap your vehicle.
Special handling may apply, See
www.dtsc.ca.gov/hazardouswaste/per
chlorate.
Your vehicle has components that may
contain perchlorate. These compo-
nents may include the airbags, seat belt
pretensioners, wireless remote control
batteries, and the batteries in the tire
pressure warning valve and transmit-
ters.
Perchlorate Material
WARNING
■General precautions while driving
Driving under the infl uence: Never drive
your vehicle when under the influence of
alcohol or drugs that have impaired your
ability to operate your vehicle. Alcohol
and certain drugs delay reaction time,
impair judgment an d reduce coordina-
tion, which could lead to an accident that
could result in death or serious injury.
Defensive driving: Always drive defen-
sively. Anticipate mi stakes that other
drivers or pedestrians might make and
be ready to avoid accidents.
Driver distraction: Always give your full
attention to driving. Anything that dis-
tracts the driver, such as adjusting con-
trols, talking on a cellular phone or
reading can result in a collision with
resulting death or serious injury to you,
your occupants or others.
■General precaution regarding chil-
dren’s safety
Never leave children unattended in the
vehicle, and never allow children to have
or use the key.
Children may be able to start the vehicle
or shift the vehicle into neutral. There is
also a danger that children may injure
themselves by playing with the windows,
the moon roof or panoramic moon roof,
or other features of the vehicle. In addi-
tion, heat build-up or extremely cold
temperatures inside the vehicle can be
fatal to children.

22Pictorial index
■Ceiling
Auxiliary box........................................................................................................... P.308
Interior light
*1......................................................................................................... P.300
Personal lights
*1.......................................................................................................P.301
Moon roof switches
*2............................................................................................ P.142
Panoramic moon roof switches
*2...................................................................... P.145
“SOS” button
*2..........................................................................................................P.60
Vanity mirrors ........................................................................................................ P.325
Sun visors ..................................................................................................................P.3 24
Inside rear view mirror .......................................................................................... P.136
Garage door opener switches ...........................................................................P.326
*1: The illustration shows the front, but they are also equipped in the rear.
*2: If equipped
A
B
C
D
E
F
G
H

331-1. For safe use
1
For safety and security
RX350L: Rear side airbags (outboard second-row seats)
Your vehicle is equipped with ADVANC ED AIRBAGS designed based on the US
motor vehicle safety standards (FMVSS20 8). The airbag sensor assembly (ECU)
controls airbag deployment based on information obtain ed from the sensors etc.
shown in the system components diagram above. This information includes crash
severity and occupant information. As th e airbags deploy, a chemical reaction in
the inflators quickly fills the airbags with no n-toxic gas to help restrain the motion of
the occupants.
■If the SRS airbags deploy (inflate)
●Slight abrasions, burns, bruising etc., may
be sustained from SRS airbags, due to the
extremely high speed deployment (infla-
tion) by hot gases.
●A loud noise and white powder will be
emitted.
●Parts of the airbag module (steering
wheel hub, airbag cover and inflator) as
well as the front seat s, parts of the front
and rear pillars, and roof side rails, may
be hot for several minutes. The airbag
itself may also be hot.
●The windshield may crack.
●All of the doors will be unlocked.
( P.98)
●The brakes and stop lights will be con-
trolled automatically. ( P.266)
●The interior lights will turn on automati-
cally. (P.301)
●The emergency flashers will turn on auto-
matically. ( P.384)
●Fuel supply to the engine will be stopped.
(P.392)
●For Lexus Enform Safety Connect sub-
scribers, if any of the following situations
occur, the system is designed to send an
emergency call to the response center,
notifying them of the vehicle’s location
(without needing to push the “SOS” but-
ton) and an agent will attempt to speak
with the occupants to ascertain the level
of emergency and assi stance required. If
the occupants are unable to communi-
cate, the agent automatically treats the
call as an emergency and helps to dis-
patch the necessary emergency services. (
P.60)
• An SRS airbag is deployed.
• A seat belt preten sioner is activated.
• The vehicle is involved in a severe rear-end collision.
■SRS airbag deployment conditions (SRS
front airbags)
●The SRS front airbags will deploy in the
event of an impact that exceeds the set
threshold level (the level of force corre-
sponding to an approximately 12 - 18
mph [20 - 30 km/h] frontal collision with
a fixed wall that does not move or
deform).
However, this threshol d velocity will be
considerably higher in the following situa-
tions:
• If the vehicle strikes an object, such as a parked vehicle or sign pole, which can
move or deform on impact
• If the vehicle is involved in an underride collision, such as a collision in which the
front of the vehicle “u nderrides”, or goes
under, the bed of a truck
●Depending on the type of collision, it is
possible that only the seat belt
pretensioners will activate.
●The SRS seat cushion airbag on the front
passenger seat will not operate if the
occupant is not wearing a seat belt.
■SRS airbag deployment conditions (SRS
side and curtain shield airbags)
●The SRS side and curtain shield airbags
will deploy in the event of an impact that
exceeds the set threshold level (the level
of force corresponding to the impact
force produced by an approximately
3300 lb. [1500 kg] vehicle colliding with
the vehicle cabin from a direction per-

351-1. For safe use
1
For safety and security
The SRS curtain shield airbags do not gen-
erally inflate if the vehicle is involved in a
rear collision, if it pitches end over end, or if
it is involved in a low-speed side or
low-speed frontal collision.
●Collision from the rear
●Pitching end over end
■When to contact your Lexus dealer
In the following cases, the vehicle will
require inspection and/or repair. Contact
your Lexus dealer as soon as possible.
●Any of the SRS airbags have been
inflated.
●The front of the vehicle is damaged or
deformed, or was involved in an accident
that was not severe enough to cause the
SRS front airbags to inflate.
●A portion of a door or its surrounding
area is damaged, deformed or has had a
hole made in it, or the vehicle was
involved in an accident that was not
severe enough to cause the SRS side and
curtain shield airbags to inflate.
●The pad section of the steering wheel,
dashboard near the front passenger
airbag or lower portio n of the instrument
panel is scratched, cracked, or otherwise
damaged.
●The front passenger’s seat cushion sur-
face is scratched, cracked, or otherwise
damaged.
●The surface of the seats with the SRS side
airbag is scratched , cracked, or other-
wise damaged.
●The portion of the fron t pillars, rear pillars
or roof side rail ga rnishes (padding) con-
taining the SRS curtain shield airbags
inside is scratched, cracked, or otherwise
damaged.

371-1. For safe use
1
For safety and security
WARNING
●The SRS front passenger airbag also
deploys with considerable force, and
can cause death or serious injury
especially if the front passenger is very
close to the airbag. The front passen-
ger seat should be as far from the
airbag as possible with the seatback
adjusted, so the front passenger sits
upright.
●Improperly seated and/or restrained
infants and children can be killed or
seriously injured by a deploying airbag.
An infant or child who is too small to
use a seat belt should be properly
secured using a child restraint system.
Lexus strongly recommends that all
infants and children be placed in the
rear seats of the vehicle and properly
restrained. The rear seats are safer for
infants and children than the front pas-
senger seat. (
P.45)
●Do not sit on the edge of the seat or
lean against the dashboard.
●Do not allow a child to stand in front of
the SRS front passenger airbag unit or
sit on the knees of a front passenger.
●Do not allow the front seat occupants
to hold items on their knees.
●Do not lean against the door, the roof
side rail or the front, side and rear pil-
lars.
●Do not allow anyone to kneel on the
passenger seats toward the door or
put their head or hands outside the
vehicle.
●Do not attach anything to or lean any-
thing against areas such as the dash-
board, steering wheel pad and lower
portion of the instrument panel.
These items can become projectiles
when the SRS driver, front passenger
and knee airbags deploy.

381-1. For safe use
WARNING
●Do not attach anything to areas such
as a door, windshield, side windows,
front or rear pillar, roof side rail and
assist grip.
●Do not hang coat hangers or other
hard objects on the coat hooks. All of
these items could become projectiles
and may cause death or serious injury,
should the SRS curtain shield airbags
deploy.
●If a vinyl cover is put on the area where
the SRS knee airbag will deploy, be
sure to remove it.
●Do not use seat accessories which
cover the parts where the SRS side
airbags and SRS seat cushion airbag
inflate as they may interfere with infla-
tion of the SRS airbags. Such accesso-
ries may prevent the side airbags and
SRS seat cushion airbag from activat-
ing correctly, disable the system or
cause the side airbags and SRS seat
cushion airbag to inflate accidentally,
resulting in death or serious injury.
●Do not strike or apply significant levels
of force to the area of the SRS airbag
components or the front doors. Doing
so can cause the SRS airbags to mal-
function.
●Do not touch any of the component
parts immediately after the SRS
airbags have deployed (inflated) as
they may be hot.
●If breathing becomes difficult after the
SRS airbags have deployed, open a
door or window to allow fresh air in, or
leave the vehicle if it is safe to do so.
Wash off any residue as soon as possi-
ble to prevent skin irritation.
●If the areas where the SRS airbags are
stored, such as the steering wheel pad
and front and rear pillar garnishes, are
damaged or cracked, have them
replaced by your Lexus dealer.
●Do not place anything, such as a cush-
ion, on the front passenger’s seat.
Doing so will disperse the passenger’s
weight, which prevents the sensor
from detecting the passenger’s weight
properly. As a result, the SRS front
airbags for the front passenger may
not deploy in the event of a collision.
■Modification and disposal of SRS
airbag system components
Do not dispose of your vehicle or per-
form any of the following modifications
without consulting your Lexus dealer.
The SRS airbags may malfunction or
deploy (inflate) accidentally, causing
death or serious injury.
●Installation, remova l, disassembly and
repair of the SRS airbags
●Repairs, modifications, removal or
replacement of the steering wheel,
instrument panel, dashboard, seats or
seat upholstery, front, side and rear pil-
lars, roof side rails, front door panels,
front door trims or front door speakers
●Modifications to the front door panel
(such as making a hole in it)
●Repairs or modifications of the front
fender, front bumper, or side of the
occupant compartment
●Installation of a grille guard (bull bars,
kangaroo bar, etc. ), snow plows,
winches or roof luggage carrier
●Modifications to the vehicle’s suspen-
sion system

451-2. Child safety
1
For safety and security
1-2.Child safety
Points to remember: P.45
Child restraint system: P.46
When using a child restraint system:
P.48
Child restraint system installation
method
• Fixed with a seat belt: P.50
• Fixed with a child restraint LATCH anchor: P.54
• Using an anchor bracket (for top tether strap): P.57
The laws of all 50 states of the U.S.A.
as well as Canada now require the use
of child restraint systems.
 Prioritize and observe the warn-
Riding with children
Observe the following precautions
when children are in the vehicle.
Use a child restraint system appro-
priate for the child, until the child
becomes large enough to properly
wear the vehicle’s seat belt.
It is recommended that children
sit in the rear seats to avoid acci-
dental contact with the shift lever,
wiper switch, etc.
 Use the rear door child-protector
lock or the window lock switch to
avoid children op ening the door
while driving or operating the
power window accidentally.
(  P.100, 142)
 Do not let small children operate
equipment which may catch or
pinch body parts, such as the
power window, hood, back door,
seats etc.
WARNING
■When children are in the vehicle
Never leave children unattended in the
vehicle, and never allow children to have
or use the key.
Children may be able to start the vehicle
or shift the vehicle into neutral. There is
also a danger that children may injure
themselves by playin g with the windows,
the moon roof or panoramic moon roof,
or other features of the vehicle. In addi-
tion, heat build-up or extremely cold
temperatures inside the vehicle can be
fatal to children.
Child restraint systems
Before installing a child restraint
system in the vehicle, there are pre-
cautions that need to be observed,
different types of child restraint sys-
tems, as well as installation meth-
ods, etc., written in this manual.
Use a child restraint system when
riding with a small child that cannot
properly use a seat belt. For the
child’s safety, install the child
restraint system to a second-row
seat. Be sure to follow the installa-
tion method that is in the operation
manual enclosed with the restraint
system.
Table of contents
Points to remember