2022 LEXUS RX350 ESP

6
Please note that this manual applies to
all models and explains all equipment,
including options. Therefore, you may
find explanations for equipment not
installed on your vehicle and the illus-
trations used may differ from your vehi-
cle.
All specifications provided in this man-
ual are current at the time of printing.
Over time, your vehicle may receive
updates that modify the vehicle and
make material in this manual incom-
plete and/or inaccurate. Because of
Lexus’ interest in continual product
improvement, Lexus reserves the right
to make changes to this manual at any
time without notice.
If Lexus chooses to update the manual,
updated versions can be viewed by
selecting your vehicle by model and
year at the following URL or on your
mobile device if you have access to the
Lexus app.
https://drivers.lexus.com
Approximately five hours after the
engine is turned off, you may hear
sound coming from under the vehicle
for several minutes. This is the sound of
a fuel evaporation leakage check and,
it does not indicate a malfunction. A wide variety of non-genuine spare
parts and accessories for Lexus vehi-
cles are currently available in the mar-
ket. You should know that Toyota does
not warrant these products and is not
responsible for their performance,
repair, or replacement, or for any dam-
age they may cause to, or adverse
effect they may have on, your Lexus
vehicle.
This vehicle should not be modified
with non-genuine Lexus products.
Modification with non-genuine Lexus
products could affect its performance,
safety or durability, and may even vio-
late governmental regulations. In addi-
tion, damage or performance
problems resulting from the modifica-
tion may not be covered under war-
ranty.
Also, remodeling like this will have an
effect on advanced safety equipment
such as Lexus Safety System + 2.0 and
there is a danger that it will not work
properly or the danger that it may work
in situations where it should not be
working.
The installation of a mobile two-way
radio system in your vehicle could
affect electronic systems such as:

Multiport fuel injection sys-
tem/sequential multiport fuel injec-
For your information
Main Owner’s Manual
Noise from under vehicle after
turning off the engine
Accessories, spare parts and
modification of your Lexus
Installation of a mobile two-way
radio system

7
tion system
 Lexus Safety System + 2.0
 Anti-lock brake system
 Vehicle dynamics integrated man-
agement
 SRS airbag system
 Seat belt pretensioner system
Be sure to check with your Lexus
dealer for precautionary measures or
special instructions regarding installa-
tion of a mobile two-way radio system.
The vehicle is equipped with sophisti-
cated computers that will record cer-
tain data, such as:
• Engine speed/Electric motor speed (traction motor speed)
• Accelerator status
•Brake status
• Vehicle speed
• Operation status of the driving assist systems
• Images from the cameras Your vehicle is equipped with cam-
eras. Contact your Lexus dealer for
the location of recording cameras.
The recorded data varies according to
the vehicle grade level and options
with which it is equipped.
These computers do not record con-
versations or sounds, and only record
images outside of the vehicle in certain
situations.
 Data Transmission
Your vehicle may transmit the data recorded in these computers to Lexus
without notification to you.

Data usage
Lexus may use the data recorded in this
computer to diagnose malfunctions, con-
duct research and development, and
improve quality.
Lexus will not disclose the recorded data to
a third party except:
• With the consent of the vehicle owner or
with the consent of the lessee if the vehi-
cle is leased
• In response to an official request by the police, a court of law or a government
agency
• For use by Lexus in a lawsuit
• For research purposes where the data is not tied to a specific vehicle or vehicle
owner
 Recorded image information can be
erased by your Lexus dealer.
The image recording function can be dis-
abled. However, if the function is disabled,
data from when the system operates will
not be available.
 To learn more abou t the vehicle data
collected, used and shared by
Lexus, please visit
www.lexus.com/privacyvts/
.
If your Lexus has Lexus Enform and if
you have subscribed to those services,
please refer to the Lexus Enform
Telematics Subscription Service
Agreement for information on data
Vehicle data recording
Usage of data collected through
Lexus Enform (U.S. mainland on-
ly)

8
collected and its usage.
To learn more about the vehicle data
collected, used and shared by Lexus,
please visit
www.lexus.com/privacyvts/
.
This vehicle is equipped with an event
data recorder (EDR). The main pur-
pose of an EDR is to record, in certain
crash or near crash-like situations, such
as an air bag deployment or hitting a
road obstacle, data that will assist in
understanding how a vehicle’s systems
performed. The EDR is designed to
record data related to vehicle dynam-
ics and safety systems for a short
period of time, typically 30 seconds or
less.
The EDR in this vehicle is designed to
record such data as:
• How various systems in your vehicle were operating;
• Whether or not the driver and pas- senger safety belts were buck-
led/fastened;
• How far (if at all) the driver was depressing the accelerator and/or
brake pedal; and,
• How fast the vehicle was traveling.
These data can help provide a better
understanding of the circumstances in
which crashes and injuries occur.
NOTE: EDR data are recorded by your
vehicle only if a non-trivial crash situa-
tion occurs; no data are recorded by
the EDR under normal driving condi-
tions and no personal data (e.g., name, gender, age, and cr
ash location) are
recorded. However, other parties, such
as law enforcement, could combine the
EDR data with the type of personally
identifying data routinely acquired
during a crash investigation.
To read data recorded by an EDR, spe-
cial equipment is required, and access
to the vehicle or the EDR is needed. In
addition to the vehicle manufacturer,
other parties, such as law enforcement,
that have the special equipment, can
read the information if they have
access to the vehicle or the EDR.
 Disclosure of the EDR data
Lexus will not disclose the data recorded in
an EDR to a third party except when:
• An agreement from the vehicle’s owner
(or the lessee for a leased vehicle) is
obtained
• In response to an official request by the police, a court of law or a government
agency
• For use by Lexus in a lawsuit
However, if necessary, Lexus may:
• Use the data for research on vehicle safety performance
• Disclose the data to a third party for research purposes without disclosing
information about the specific vehicle or
vehicle owner
The SRS airbag and seat belt
pretensioner devices in your Lexus
contain explosive chemicals. If the
vehicle is scrapped with the airbags
and seat belt pretensioners left as they
Event data recorder
Scrapping of your Lexus

241-1. For safe use
1-1.For safe use
Use only floor mats designed specifi-
cally for vehicles of the same model
and model year as your vehicle. Fix
them securely in place onto the carpet.
1Insert the retaining hooks (clips)
into the floor mat eyelets.
2 Turn the upper knob of each retain-
ing hook (clip) to secure the floor
mats in place.
Always align the marks .
The shape of the reta ining hooks (clips)
may differ from that shown in the illustra-
tion.
Before driving
Observe the following before start-
ing off in the vehicle to ensure
safety of driving.
Installing floor mats
A
WARNING
Observe the following precautions.
Failure to do so may cause the driver’s
floor mat to slip, possibly interfering with
the pedals while driving. An unexpect-
edly high speed may result or it may
become difficult to stop the vehicle. This
could lead to an accident, resulting in
death or serious injury.
■When installing the driver’s floor mat
●Do not use floor mats designed for
other models or di fferent model year
vehicles, even if they are Lexus Genu-
ine floor mats.
●Only use floor mats designed for the
driver’s seat.
●Always install the floor mat securely
using the retaining hooks (clips) pro-
vided.
●Do not use two or more floor mats on
top of each other.
●Do not place the floor mat bot-
tom-side up or upside-down.
■Before driving
●Check that the floor mat is securely
fixed in the correct place with all the
provided retaining hooks (clips). Be
especially careful to perform this
check after cleaning the floor.
●With the engine stopped and the shift
lever in P, fully depress each pedal to
the floor to make sure it does not inter-
fere with the floor mat.

331-1. For safe use
1
For safety and security
RX350L: Rear side airbags (outboard second-row seats)
Your vehicle is equipped with ADVANC ED AIRBAGS designed based on the US
motor vehicle safety standards (FMVSS20 8). The airbag sensor assembly (ECU)
controls airbag deployment based on information obtain ed from the sensors etc.
shown in the system components diagram above. This information includes crash
severity and occupant information. As th e airbags deploy, a chemical reaction in
the inflators quickly fills the airbags with no n-toxic gas to help restrain the motion of
the occupants.
■If the SRS airbags deploy (inflate)
●Slight abrasions, burns, bruising etc., may
be sustained from SRS airbags, due to the
extremely high speed deployment (infla-
tion) by hot gases.
●A loud noise and white powder will be
emitted.
●Parts of the airbag module (steering
wheel hub, airbag cover and inflator) as
well as the front seat s, parts of the front
and rear pillars, and roof side rails, may
be hot for several minutes. The airbag
itself may also be hot.
●The windshield may crack.
●All of the doors will be unlocked.
( P.98)
●The brakes and stop lights will be con-
trolled automatically. ( P.266)
●The interior lights will turn on automati-
cally. (P.301)
●The emergency flashers will turn on auto-
matically. ( P.384)
●Fuel supply to the engine will be stopped.
(P.392)
●For Lexus Enform Safety Connect sub-
scribers, if any of the following situations
occur, the system is designed to send an
emergency call to the response center,
notifying them of the vehicle’s location
(without needing to push the “SOS” but-
ton) and an agent will attempt to speak
with the occupants to ascertain the level
of emergency and assi stance required. If
the occupants are unable to communi-
cate, the agent automatically treats the
call as an emergency and helps to dis-
patch the necessary emergency services. (
P.60)
• An SRS airbag is deployed.
• A seat belt preten sioner is activated.
• The vehicle is involved in a severe rear-end collision.
■SRS airbag deployment conditions (SRS
front airbags)
●The SRS front airbags will deploy in the
event of an impact that exceeds the set
threshold level (the level of force corre-
sponding to an approximately 12 - 18
mph [20 - 30 km/h] frontal collision with
a fixed wall that does not move or
deform).
However, this threshol d velocity will be
considerably higher in the following situa-
tions:
• If the vehicle strikes an object, such as a parked vehicle or sign pole, which can
move or deform on impact
• If the vehicle is involved in an underride collision, such as a collision in which the
front of the vehicle “u nderrides”, or goes
under, the bed of a truck
●Depending on the type of collision, it is
possible that only the seat belt
pretensioners will activate.
●The SRS seat cushion airbag on the front
passenger seat will not operate if the
occupant is not wearing a seat belt.
■SRS airbag deployment conditions (SRS
side and curtain shield airbags)
●The SRS side and curtain shield airbags
will deploy in the event of an impact that
exceeds the set threshold level (the level
of force corresponding to the impact
force produced by an approximately
3300 lb. [1500 kg] vehicle colliding with
the vehicle cabin from a direction per-

361-1. For safe use
WARNING
■SRS airbag precautions
Observe the following precautions
regarding the SRS airbags.
Failure to do so may cause death or seri-
ous injury.
●The driver and all passengers in the
vehicle must wear their seat belts
properly.
The SRS airbags are supplemental
devices to be used with the seat belts.
●The SRS driver airbag deploys with
considerable force, and can cause
death or serious injury especially if the
driver is very close to the airbag.
The National Highway Traffic Safety
Administration (NHTSA) advises:
Since the risk zone for the driver’s
airbag is the first 2 - 3 in. (50 - 75 mm)
of inflation, placing yourself 10 in. (250
mm) from your driver airbag provides
you with a clear margin of safety. This
distance is measured from the center
of the steering wheel to your breast-
bone. If you sit less than 10 in. (250
mm) away now, you can change your
driving position in several ways:
• Move your seat to the rear as far as you can while still reaching the pedals
comfortably.
• Slightly recline the back of the seat.Although vehicle designs vary, many
drivers can achieve the 10 in. (250
mm) distance, even with the driver seat
all the way forward, simply by reclining
the back of the seat somewhat. If
reclining the back of your seat makes it
hard to see the road, raise yourself by
using a firm, non-slippery cushion, or
raise the seat if your vehicle has that
feature.
•If your steering whee l is adjustable, tilt
it downward. This points the airbag
toward your chest instead of your head
and neck.
The seat should be adjusted as recom-
mended by NHTSA above, while still
maintaining control of the foot pedals,
steering wheel, and your view of the
instrument panel controls.
●If the seat belt extender has been con-
nected to the front seat belt buckles
but the seat belt extender has not also
been fastened to the latch plate of the
seat belt, the SRS front airbags will
judge that the driver and front passen-
ger are wearing the seat belt even
though the seat belt has not been con-
nected. In this case, the SRS front
airbags may not activate correctly in a
collision, resulting in death or serious
injury in the event of a collision. Be
sure to wear the seat belt with the seat
belt extender.

371-1. For safe use
1
For safety and security
WARNING
●The SRS front passenger airbag also
deploys with considerable force, and
can cause death or serious injury
especially if the front passenger is very
close to the airbag. The front passen-
ger seat should be as far from the
airbag as possible with the seatback
adjusted, so the front passenger sits
upright.
●Improperly seated and/or restrained
infants and children can be killed or
seriously injured by a deploying airbag.
An infant or child who is too small to
use a seat belt should be properly
secured using a child restraint system.
Lexus strongly recommends that all
infants and children be placed in the
rear seats of the vehicle and properly
restrained. The rear seats are safer for
infants and children than the front pas-
senger seat. (
P.45)
●Do not sit on the edge of the seat or
lean against the dashboard.
●Do not allow a child to stand in front of
the SRS front passenger airbag unit or
sit on the knees of a front passenger.
●Do not allow the front seat occupants
to hold items on their knees.
●Do not lean against the door, the roof
side rail or the front, side and rear pil-
lars.
●Do not allow anyone to kneel on the
passenger seats toward the door or
put their head or hands outside the
vehicle.
●Do not attach anything to or lean any-
thing against areas such as the dash-
board, steering wheel pad and lower
portion of the instrument panel.
These items can become projectiles
when the SRS driver, front passenger
and knee airbags deploy.

601-3. Lexus Enform
1-3.Lexus Enform
*:If equipped
“SOS” button
LED light indicators
Microphone
Lexus Enform Safety Con-
nect
*
Safety Connect is a subscrip-
tion-based telematics service that
uses Global Positioning System
(GPS) data and embedded cellular
technology to provide safety and
security features to subscribers.
Safety Connect is supported by
Lexus’ designated response center,
which operates 24 hours per day, 7
days per week.
Safety Connect service is available
by subscription on select,
telematics hardware-equipped
vehicles.
By using the Safety Connect ser-
vice, you are agreeing to be bound
by the Telematics Subscription Ser-
vice Agreement and its Terms and
Conditions, as in effect and
amended from time to time, a cur-
rent copy of which is available at
Lexus.com. All use of the Safety
Connect service is subject to such
then-applicable Terms and Condi-
tions.
System components
A
B
C