
3
1
9 8
7 5 4
3
2
IS350/250_U (OM53758U)
6
4-1. Before drivingDriving the vehicle ......................146
Cargo and luggage.....................153
Vehicle load limits ........................156
Trailer towing ................................. 157
Dinghy towing .............................. 158
4-2. Driving procedures Engine (ign ition) switch .............159
Automatic transmission ............164
Turn signal lever ............................ 170
Parking brake ................................ 172
4-3. Operating the lights and wipers
Headlight switch .......................... 173
Automatic High Beam............... 176
Fog light switch .............................. 181
Windshield wipers and washer .......................................... 182
4-4. Refueling Opening the fuel tank cap ...... 188 4-5. Using the driving support
systems
Cruise control ...............................192
Dynamic radar cruise control ...........................................196
LDA (Lane Departure Alert)........208
Intuitive parking assist ................ 214
Rear view monito r system ........ 221
Driving mode select switch .............................................231
Driving assist systems .............. 234
PCS (Pre-Collision System) ......... 240
BSM (Blind Spot Monitor) ..............246
• The Blind Spot Monitor function .....................................249
• The Rear Cross Traffic Alert function ..........................251
4-6. Driving tips Winter driving tips ..................... 254
4Driving

7
1
9 8
7 5 4
3
2
IS350/250_U (OM53758U)
6
9-1. SpecificationsMaintenance data (fuel, oil level, etc.) ..................500
Fuel information........................... 510
Tire information.............................513
9-2. Customization Customizable features ............ 525
9-3. Items to initialize Items to initialize ......................... 534
Reporting safety defects for U.S. owners ............................... 536
Seat belt instructions for Canadian owners
(in French).................................. 537
SRS airbag instructions for Canadian owners
(in French).................................. 538 What to do if...
(Troubleshooting) ................. 548
Alphabetical index ............................... 552
9Vehicle specifications
For owners
Index
For vehicles with a navigation system, refer to the “Navigation System Owner’s
Manual” for information regarding the equipment listed below.
• Navigation system
• Audio/video system•Intuitive parking assist
•Rear view monitor system

15Pictorial index
IS350/250_U (OM53758U)
Windshield wipers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Precautions against winter season . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 254
To prevent freezing (windshield wiper de-icer)
* . . . . . . . . . . . . . . . . . . . . . . . P. 350
Precautions against car wash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 385
Fuel filler door . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 1 8 8
Refueling method . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 188
Fuel type/fuel tank capacity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 502
Tires . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 411
Tire size/inflation pressure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 507
Winter tires/tire chain. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 254
Checking/rotation/tire pressure warning system . . . . . . . . . . . . . . . . . . . . . . . . . P. 411
Coping with flat tires . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 475
Hood . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 399
Opening. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 399
Engine oil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 502
Coping with overheat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 494
Warning messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 46 3
Headlights/parking lights/daytime running lights . . . . . . . . . . . . . . . . . . . P. 173
Fog lights
* . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 181
Turn signal lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 170
Tail lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 173
Stop lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 146
License plate lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 17 3
Back-up lights
Shifting the shift lever to R . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 16 4
Side marker lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 173
4
5
6
7
Light bulbs of the exterior lights for driving(Replacing method: P. 432, Watts: P. 509)
*: If equipped
8
9
10
11
12
13
14
15

17Pictorial index
IS350/250_U (OM53758U)
Multi-information display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 86
Display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 86
When the warning messages are displayed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 461
Parking brake . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 172
Applying/releasing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 1 7 2
Precautions against winter season . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 255
Warning buzzer/message . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 461
Turn signal lever. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 170
Headlight switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 173
Headlights/parking lights/tail lights/daytime running lights . . . . . . . . . . . . . . P. 173
Fog lights
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 181
Windshield wiper and washer switch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Adding washer fluid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 410
Warning messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 468
Emergency flasher switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 446
Trunk opener. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 109
Hood lock release lever . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 399
Tilt and telescopic steering control switch
*1. . . . . . . . . . . . . . . . . . . . . . . . P. 130
Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 130
Driving position memory
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 123
Tilt and telescopic steering lock release lever*1. . . . . . . . . . . . . . . . . . . . P. 130
Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 130
Air conditioning system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 346
Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 346
Rear window defogger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 350
Audio system*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 260
Audio system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 260
Hands-free system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 311
Trunk opener main switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 110
*1: If equipped
*2: For vehicles with a navigation system, refer to “Navigation System Owner's Manual”.
4
5
6
7
8
9
10
11
12
13
14
15

18Pictorial index
IS350/250_U (OM53758U)
■Switches
Automatic high beam switch*1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 176
Windshield wiper de-icer switch
*1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 350
Odometer/trip meter and trip meter reset button . . . . . . . . . . . . . . . . . . P. 83
Instrument panel light control swit ches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 84
Rear sunshade switch
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 367
Intuitive parking assist switch
*1, 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 214
BSM (Blind Spot Monitor) main switch
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 246
1
2
3
4
5
6
7

681-1. For safe use
IS350/250_U (OM53758U)
Exhaust gas precautions
Harmful substance to the human body is included in exhaust gases if inhaled.
CAUTION
Exhaust gases include harmful carbon monoxi de (CO), which is colorless and odorless.
Observe the following precautions.
Failure to do so may cause exhaust gases enter the vehicle and may lead to an accident
caused by light-headedness, or may lead to death or a serious health hazard.
■Important points while driving
●Keep the trunk lid closed.
●If you smell exhaust gases in the vehicle ev en when the trunk lid is closed, open the
windows and have the vehicle inspected at your Lexus dealer as soon as possible.
■When parking
●If the vehicle is in a poorly ventilated area or a closed area, such as a garage, stop the
engine.
●Do not leave the vehicle with the engine on for a long time.
If such a situation cannot be avoided, park the vehicle in an open space and ensure
that exhaust fumes do not enter the vehicle interior.
●Do not leave the engine running in an area with snow build-up, or where it is snowing.
If snowbanks build up around the vehicle wh ile the engine is running, exhaust gases
may collect and enter the vehicle.
■Exhaust pipe
The exhaust system needs to be checked periodically. If there is a hole or crack caused
by corrosion, damage to a joint or abnormal exhaust noise, be sure to have the vehicle
inspected and repaired by your Lexus dealer.

782. Instrument cluster
IS350/250_U (OM53758U)
*1: These lights turn on when the engine switch is turned to IGNITION ON mode to indicate that a system check is being perfor med. They will turn off after the engine is
on, or after a few seconds. There may be a ma lfunction in a system if the lights do not
come on, or turn off. Have the vehi cle inspected by your Lexus dealer.
*2: The light flashes to indicate a malfunction.
The indicators inform the driver of the operating state of the vehicle’s various sys-
tems.
Indicators
Turn signal indicator
( P. 1 7 0 )
(if equipped)
LDA (Lane Departure
Alert) indicator ( P. 2 0 8 )
(U.S.A.)
Headlight indicator
( P. 1 7 3 )
(if equipped)
Intuitive parking assist indi-
cator ( P. 2 1 4 )
(Canada)
Tail light indicator
( P. 1 7 3 ) *1, 2 Slip indicator ( P. 2 3 5 )
Headlight high beam indi-
cator ( P. 1 74 )
*1VSC OFF indicator
( P. 2 3 6 )
(if equipped)
Automatic High Beam indi-
cator ( P. 1 76 )*1, 3
(if equipped)
Pre-collision system warn-
ing light
( P. 241)
(if equipped)
Fog light indicator
( P. 1 8 1 )*4, 5
(if equipped)
BSM (Blind Spot Monitor)
outside rear view mirror
indicators ( P. 2 4 6 )
Cruise control indicator
( P. 192, 196)
*6Security indicator
( P. 6 9 , 7 1 )
(if equipped)
Dynamic radar cruise con-
trol indicator ( P. 1 9 6 )*7Low outside temperature
indicator ( P. 8 1 )
Cruise control “SET” indica-
tor (P. 192, 196)
*1Eco Driving Indicator Light
( P. 9 0 )

1003-1. Key information
IS350/250_U (OM53758U)
■Card key (if equipped)
●The card key is not waterproof.
●The mechanical key that is st ored inside the card key should be used only if a problem
arises, such as when the card key does not operate properly.
●If it is difficult to take out the mechanical key, push down the lock release button using a
pen tip etc. If it is still difficult to pull it out, use a coin etc.
■When required to leave the vehicle’s key with a parking attendant
Set the luggage security system ( P. 110) on and lock the glove box ( P. 359) as cir-
cumstances demand.
Remove the mechanical key for your own use and provide the attendant with the elec-
tronic key only.
■If you lose your mechanical keys
New genuine mechanical keys can be made by your Lexus dealer using another
mechanical key and the key number stamped on your key number plate. Keep the plate
in a safe place such as your wallet, not in the vehicle.
■When riding in an aircraft
When bringing an electronic key onto an aircraft, make sure you do not press any but-
tons on the electronic key while inside the airc raft cabin. If you are carrying an electronic
key in your bag etc., ensure that the buttons are not likely to be pressed accidentally.
Pressing a button may cause the electronic key to emit radio waves that could interfere
with the operation of the aircraft.
●To store the mechanical key in the card key,
insert it while pressing the lock release button.
●If the battery cover is not installed and the bat-
tery falls out or if the battery was removed
because the key got wet, reinstall the battery
with the positive terminal facing the Lexus
emblem.