
1, 2, 3 ...
4-ETS see ETS/4-ETS                                          
4MATIC
see All-wheel drive (4MATIC)                    
A
ABS (Antilock Brake System)  ............. 62
Indicator lamp ................................ 305
Messages in the multifunction
display  ................................... 288, 289
Accessory weight  .............................. 249
Accidents  ........................................... 112
Air bags  ........................................... 37
Emergency calls (Tele Aid)  .............208
NECK-PRO active front head
restraints   ........................................ 54
Active Bi-Xenon headlamps
see Headlamps                                         
Adaptive Brake  .................................... 64
Adaptive Highbeam Assist  ............... 100
Switching on or off ......................... 142
AdBlue ®
 ...................................... 333, 364
Refilling   ......................................... 334
Additives  
Engine oil  ....................................... 362
Gasoline ......................................... 364
Address change  ................................... 21
Advanced Tire Pressure
Monitoring System (Advanced
TPMS)  ................................................. 233
Messages in the multifunction
display  ........................................... 285
Air bags  ................................................ 37
Emergency call upon deployment  ..208
Front, driver and passenger  .............40
Front passenger front air bag off
indicator lamp (Canada
only)  ........................................ 46, 313
Front passenger front air bag off
indicator lamp (USA only)  ........43, 314
Knee bag .......................................... 40
Messages in the multifunction
display  ........................................... 276
OCS (Occupant Classification
System)  ........................................... 43
Pelvis ............................................... 42
Safety guidelines  ............................. 39
Side impact  ...................................... 41
Window curtain  ................................ 42
Air conditioning refrigerant and
lubricant  ............................................. 362
Air distribution  .................................. 189
Air filter  .............................................. 299
AIRMATIC  
Damping system  ............................ 163
Introduction  ................................... 163
Messages in the multifunction
display  ........................................... 292
Vehicle level control  ......................163
Air pressure
see Tire inflation pressure                        
Air pressure (tires)  ............................ 250
Air pump (electric)  ............................ 327
Air recirculation mode  ...................... 190
Air volume  .......................................... 189
Alarm system see Anti-theft systems                              
Alignment bolt (vehicle tool kit)  ...... 326
All-wheel drive (4MATIC)  .................. 161
Alternator  
Messages in the multifunction
display  ................................... 284, 297
Alternator (Technical data)
see Vehicle specification                          
AMG adaptive sport suspension
system (E 63 AMG)  ............................ 164
AMG menu  ......................................... 131
Anticorrosion/antifreeze  .................. 365
Antilock Brake System see ABS                                                     
Anti-theft systems  ............................... 71
Anti-theft alarm system  ...................72
Immobilizer  ...................................... 71
Aquaplaning
see Hydroplaning                                      
Armrest, front  
Storage compartment  ....................202
Armrest, rear  
Storage compartment  ....................202
Ashtrays  ............................................. 206
Aspect ratio (tires)  ............................ 250
Assistance menu  ............................... 1374Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 4 

ATTENTION ASSIST ........................... 178
Messages in the multifunction
display  ........................................... 292
Switching on or off ......................... 138
Audio menu  ........................................ 134
Auto-dimming rear view mirrors  ........ 95
Automatic central locking  .......... 80, 144
Automatic climate control see Climate control system                      
Automatic headlamp mode  ................ 98
Automatic interior lighting control  .. 103
Automatic locking when driving  ...... 144
Automatic shift program  .................. 120
Automatic transmission  ................... 114
Automatic shift program  ................120
Gear range indicator  ......................120
Gear ranges  ................................... 120
Gear selector lever  ........................115
Hill-start assist system  ..................160
Kickdown  ....................................... 119
Kickdown (manual shift program)  ..124
Manual shift program ..................... 122
One-touch gearshifting  ..................121
Program mode indicator  ................121
Program mode selector dial
(E 63 AMG)  ............................ 121, 123
Program mode selector switch
(automatic shift program)  ..............120
Shifting procedure  .........................118
Steering wheel gearshift control  ....122
Transmission position indicator  .....118
Transmission positions  ..................118
AUX socket  ........................................ 201
Axle oils  .............................................. 360
B
BabySmart™  
Air bag deactivation system  .............46
Self-test  ........................................... 47
Backrest
see Seats                                                  
Backup lamps  
Messages in the multifunction
display  ........................................... 300
Bar (air pressure unit)  ....................... 250
BAS (Brake Assist System)  ................. 63
BAS PLUS (Brake Assist System
PLUS)  .................................................... 63
Batteries, SmartKey  
Checking condition  ..........................79
Replacing  ....................................... 317
Battery, Vehicle  ................................. 336
Charging  ........................................ 337
Jump starting  ................................. 338
Messages in the multifunction
display  ................................... 284, 297
Bead (tire)  .......................................... 250
Beverage holders see Cup holders                                        
Bleeding the fuel system (diesel
engine)  ............................................... 333
Blind Spot Assist  ............................... 175
Messages in the multifunction
display  ........................................... 281
Switching on or off ......................... 138
BlueTEC  
AdBlue ®
 tank  ................................. 333
Brake Assist System
see BAS                                                     
Brake Assist System PLUS
see BAS PLUS                                           
Brake fluid  
Checking level  ............................... 227
Messages in the multifunction
display  ........................................... 289
Brake lamps  
Cleaning lenses  ............................. 262
Brake pads  
Messages in the multifunction
display  ........................................... 287
Brakes  ................................................ 254
Ceramic brake system  ...................256
High-performance brake system  ....256
Parking brake  ................................ 113
Warning lamp ................................. 305
Break-in period  .................................. 220
Bug cover (Radiator)  ......................... 224
Bulbs see Replacing bulbs                                  Index5212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 5 

ESC (Electronic Stability Control) ...... 65
ETS/4-ETS  ....................................... 65
Messages in the multifunction
display  ........................... 288, 289, 290
Warning lamp ................................. 309
ETD (Emergency Tensioning
Device)  ................................................. 52
Safety guidelines  ............................. 39
ETS/4-ETS (Electronic Traction
System)  ................................................ 65
Express operation  
Panorama roof  ............................... 195
Power windows  .............................. 105
Tilt/sliding sunroof  ........................192
Exterior lamp switch  ........................... 97
Exterior rear view mirrors  .................. 95
Parking position  ............................... 95
Exterior view of vehicle  ...................... 26
F
Fastening the seat belts  ..................... 50
First aid kit  ......................................... 268
Flat tire  ............................................... 323
Lowering the vehicle  ......................328
Mounting the spare wheel  .............323
Preparing the vehicle  .....................323
Spare wheel ........................... 323, 358
TIREFIT (tire repair kit)  ...................329
Floormats  ........................................... 217
Fluids  
Automatic transmission fluid  .........360
Brake fluid  ..................................... 361
Capacities  ...................................... 359
Engine coolant  ............................... 361
Engine oil  ....................................... 360
Power steering fluid  .......................360
Washer and headlamp cleaning
system  ........................................... 361
Fog lamps  ............................................. 99
Messages in the multifunction
display  ................................... 300, 302
Four-wheel drive
see All-wheel drive (4MATIC)                    
Front air bags
see Air bags                                              
Front axle oil  ...................................... 360
Front lamps
see Headlamps                                         
Front passenger front air bag  ............ 40
Messages in the multifunction
display  ........................................... 276
Front passenger front air bag off
indicator lamp (Canada only)  ..... 46, 313
Front passenger front air bag off
indicator lamp (USA only)  .......... 43, 314
Fuel  ..................................................... 220
Additives  ........................................ 364
Capacity, fuel tank  .........................361
Diesel fuel  ...................................... 363
Drive sensibly–safe fuel  .................254
Fuel consumption statistics  ...........130
Fuel filler flap and cap  ...................222
Fuel tank reserve warning lamp  .....310
Premium unleaded gasoline  ...........362
Refueling ........................................ 220
Requirements  ................................ 363
Fuel filler flap  ..................................... 222
Opening manually  ..........................316
Fuel gauge  ......................................... 126
Fuels, coolants, lubricants etc.  ........ 359
Fuel system, bleeding (diesel
engine)  ............................................... 333
Fuel tank  
Capacity  ........................................ 361
Fuel filler flap and cap  ...................222
Refueling ........................................ 220
Fuses  .................................................. 343
G
Garage door opener  .................... 33, 212
Gasoline see Fuel                                                     
GAWR (Gross Axle Weight Rating)  ... 250
Gear range  ......................................... 120
Indicator  ........................................ 120
Limiting  .......................................... 122
Shifting into optimal  ......................122
Gear selector lever  ............................ 115
Cleaning ......................................... 265
Gearshift pattern  ........................... 115
Shifting procedure  .........................118
Transmission position indicator  .....118
Transmission positions  ..................118
Index9212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 9 

Generatorsee Alternator                                           
Global locking/unlocking
see Key, SmartKey                                    
Glove box  ........................................... 201
Gross Axle Weight Rating see GAWR                                                 
Gross Vehicle Weight
see GVW                                                    
Gross Vehicle Weight Rating
see GVWR                                                 
GVW (Gross Vehicle Weight)  ............ 250
GVWR (Gross Vehicle Weight
Rating)  ................................................ 250
H
Halogen headlamps see Headlamps                                         
Hard plastic trim items, cleaning  .... 265
Hazard warning flasher  .................... 101
Headlamp cleaning system  .............. 102
Headlamps  
Active Bi-Xenon headlamps  .............97
Adaptive Highbeam Assist  .............100
Automatic headlamp mode  ..............98
Bi-Xenon  .................................. 97, 319
Cleaning lenses  ............................. 262
Cleaning system  ............................ 102
Daytime running lamp mode  ............98
Delayed shut-off  ............................ 142
Halogen  ......................................... 319
High-beam flasher  .........................101
High-beam headlamps  ...................100
Low-beam headlamps  ......................98
Messages in the multifunction
display  ........................................... 299
Replacing bulbs  ............................. 318
Switch  .............................................. 97
Headliner and shelf below rear
window, cleaning and care of  .......... 266
Head restraints  .................................... 87
Adjustment  ................................ 87, 89
Comfort head restraint  ....................89
Folding back  .................................... 89
NECK-PRO active front head
restraints  ......................................... 54
Rear seat head restraints ................. 89
Heated steering wheel  ........................ 94
Height adjustment  
Seat belt outlet  ................................ 51
Seats  ............................................... 87
Vehicle level control  ......................163
High-beam flasher  ............................. 101
High-beam headlamps  .............. 100, 319
Adaptive Highbeam Assist  .............100
Indicator lamp .................................. 29
Replacing bulbs  ............................. 319
High-performance brake system  ..... 256
Hill-start assist system  ..................... 160
HOLD function  ................................... 161
Hood  ................................................... 223
Messages in the multifunction
display  ........................................... 293
Hydroplaning  ..................................... 257
I
Identification labels  .......................... 346
Identification number, vehicle
(VIN)  ................................................... 346
Ignition  ................................... 85, 86, 110
Immobilizer  .......................................... 71
Indicator lamps see Lamps, indicator and warning            
Infant and child restraint systems
see Children in the vehicle                        
Inflation pressure
see Tires, Inflation pressure                      
Inside door handle  .............................. 80
Instrument cluster  ...................... 28, 125
Illumination  .................................... 125
Lamps  ............................................ 304
Multifunction display  .....................128
Instrument lighting
see Instrument cluster, Illumination         
Instrument panel
see Instrument cluster                              
Instruments and controls
see Cockpit                                               
Interior lighting  
Delayed shut-off  ............................ 143
Emergency lighting  ........................103
Front  .............................................. 103
Front reading lamps  .......................103
10Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 10 

Rear ............................................... 104
Rear reading lamps  ........................104
Interior rear view mirror  ..................... 94
Auto-dimming rear view mirrors ....... 95
Interior storage spaces
see Storage compartments                      
Intermittent wiping  ........................... 104
Rain sensor  .................................... 104
IR emitter  
Replacing bulbs  ............................. 319
ISOFIX (Child seat anchors –
LATCH-type) see Children in the vehicle                        
J
Jack  ..................................................... 270
Jump starting  ..................................... 338
K
Key, Mechanical  
Loss of  ............................................. 79
Replacing  ......................................... 80
Unlocking/locking manually  ..........314
Valet locking  .................................... 85
Key, SmartKey  
Battery check lamp  ..........................79
Checking batteries  ...........................79
Factory setting ........................... 77, 79
Global locking (KEYLESS-
GO)  .................................................. 79
Global locking (SmartKey) ................ 77
Global unlocking (KEYLESS-
GO)  .................................................. 79
Global unlocking
(SmartKey)  ....................................... 77
Important notes on KEYLESS-GO  .....78
Locking/unlocking ........................... 76
Loss of  ............................................. 79
Messages in the multifunction
display  ........................................... 293
Opening, trunk  ................................. 82
Opening and closing the power
tilt/sliding sunroof or the
panorama roof  ............................... 107
Opening and closing the windows . 107
Remote control  ................................ 76
Replacing ......................................... 80
Replacing batteries  ........................317
Restoring to factory setting  .......77, 79
Selective setting  ........................77, 79
Starter switch positions  ...................85
KEYLESS-GO  
Starter switch positions  ...................86
Kickdown  ........................................... 119
Kickdown (manual shift program)  ... 124
Kilopascal (air pressure unit)  ........... 250
Knee bag  .............................................. 40
L
Labels  
Certification  ................................... 346
Emission control information  .........347
Tire and Loading Information
placard ........................................... 237
Tire inflation pressure  ....................230
Lamps, exterior  
Exterior lamp switch  ........................97
Front  .............................................. 319
Messages in the multifunction
display  ........................................... 299
Switching on/off .............................. 97
Lamps, indicator and warning  
ABS .......................................... 29, 305
Adaptive Highbeam Assist  .............100
Brakes  ........................................... 305
Coolant  .......................................... 311
Distance warning lamp  ..........151, 309
Engine malfunction  ........................310
ESC  .......................................... 29, 309
ESC OFF  ........................................ 308
Fog lamps  ........................................ 99
Front passenger front air bag off
(Canada only)  .......................... 46, 313
Front passenger front air bag off
(USA only) ................................ 43, 314
Fuel tank reserve  ........................... 310
High-beam headlamps  .............29, 100
Instrument cluster  .........................304
Low-beam headlamps  ................30, 98
Low tire pressure/TPMS
malfunction telltale  ........................312
Seat belt telltale  ................29, 52, 307
Index11212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 11 

SRS .......................................... 36, 308
Turn signals  ..................................... 29
Lane Keeping Assist  .......................... 177
Messages in the multifunction
display  ........................................... 283
Switching on or off ......................... 138
LATCH-type child seat anchors (ISOFIX)
see Children in the vehicle                        
License plate lamps  
Messages in the multifunction
display  ........................................... 301
Light alloy wheels, cleaning  ............. 265
Lighter see Cigarette lighter                                 
Lighting  ................................................ 97
Daytime running lamp mode  ............98
Exterior  ............................................ 97
Interior  ........................................... 103
Limp-home mode  .............................. 124
Load index (tires)  ...................... 246, 250
Loading see Vehicle loading                                   
Locator lighting  ................................. 142
Locking the vehicle  
KEYLESS-GO  .................................... 77
Manually  ........................................ 315
SmartKey  ......................................... 76
Loss of  
Key  .................................................. 79
Service and Warranty Information
booklet  .......................................... 346
Low-beam headlamps  ......................... 98
Exterior lamp switch  ........................97
Indicator lamp .................................. 30
Replacing bulbs  ............................. 319
Switching on  .................................... 98
Lubricants  .......................................... 359
Lumbar support  ................................... 89
M
Maintenance  ........................................ 21
Maintenance System  
Service indicator display  ................259
Service indicator message  .............258
Service term exceeded  ..................259
Manual headlamp mode (Low-
beam headlamps)  ................................ 98
Manual shift program  ....................... 122
Maximum engine speed see Vehicle specification                          
Maximum loaded vehicle weight  ..... 250
Maximum load rating (tires)  ............. 250
Maximum permissible tire
inflation pressure  .............................. 251
Mechanical key see Key, Mechanical                                 
Media interface  ................................. 201
Memory function  ................................. 96
Menus see Control system menus                       
Minispare wheel
see Spare wheel                                        
Mirrors  .................................................. 94
Auto-dimming rear view mirrors ....... 95
Exterior rear view mirror parking
position  ............................................ 95
Exterior rear view mirrors  ................95
Interior rear view mirror  ...................94
Memory function .............................. 96
Vanity mirror  .................................. 205
MOExtended system  ......................... 329
MOExtended tires  ..................... 329, 353
MON (Motor Octane Number)  .......... 363
Motor Octane Number see MON                                                   
Multifunction display  ........................ 128
Symbol messages  ..........................287
Text messages  ............................... 274
Vehicle status messages  ...............272
Multifunction display messages  
ABS  ....................................... 288, 289
Active headlamps  .......................... 299
Advanced TPMS  ............................. 285
Air bags  ......................................... 276
Air filter .......................................... 299
AIRMATIC  ...................................... 292
Alternator  .............................. 284, 297
ATTENTION ASSIST  ........................292
Automatic
transmission  .......................... 283, 284
Backrests ....................................... 293
Battery  ................................... 284, 297
Blind Spot Assist ............................ 281
Brake fluid  ..................................... 28912Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 12 

T
Tachometer  .................................. 28, 126
Overspeed range  ........................... 126
Tail lamps  
Cleaning lenses  ............................. 262
Tar stains  ........................................... 261
Technical data  
Air conditioning refrigerant  ............362
Brake fluid  ..................................... 362
Capacities fuels, coolants,
lubricants etc.  ................................ 359
Coolant  .......................................... 365
Engine oil additives  ........................362
Engine oils  ..................................... 361
Fuel requirements .......................... 363
Gasoline additives .......................... 364
Identification labels  .......................346
Premium unleaded gasoline  ...........362
Rims and tires  ................................ 353
Spare wheel  ................................... 358
Vehicle specification E 350 ............ 348
Vehicle specification
E 350 4MATIC ................................ 349
Vehicle specification
E 350 BlueTEC  ............................... 348
Vehicle specification E 550 ............ 350
Vehicle specification
E 550 4MATIC ................................ 351
Vehicle specification E 63 AMG  .....352
Washer and headlamp cleaning
system  ................................... 361, 367
Technical data (dimensions)
see Vehicle specification                          
Technical data (electrical system)
see Vehicle specification                          
Technical data (engine)
see Vehicle specification                          
Technical data (weights)
see Vehicle specification                          
Tele Aid  ............................................... 207
Emergency calls  ............................. 208
Information button  .........................210
Initiating an emergency call
manually  ........................................ 209
Messages in the multifunction
display  ........................................... 290
Remote door lock  .......................... 212Remote door unlock  ......................211
Roadside Assistance button  ..........210
Search & Send  ............................... 211
SOS button  .................................... 209
Stolen Vehicle Recovery Services  ..212
System self-test  ............................. 208
Telephone  ............................................. 30
Answering/ending a call  ................136
Hands-free microphone  ...................33
Menu  ............................................. 135
Operation ....................................... 135
Phone book .................................... 136
Redialing  ........................................ 137
Temperature  
Coolant  .......................................... 125
Interior temperature  ......................186
Outside  .......................................... 126
Tether anchorage points
see Children in the vehicle                        
Through-loading feature  ................... 198
Tie-down rings  ................................... 199
Tightening torque  
Wheels  ........................................... 328
TIN (Tire Identification Number)  ...... 251
Tire and Loading Information
placard  ............................................... 237
Tire and loading terminology  ........... 249
TIREFIT  ............................................... 329
Tire Identification Number see TIN                                                      
Tire inflation pressure  
Checking ........................................ 231
Important notes on  ........................230
Label on the inside of fuel filler
flap  ................................................ 230
Placard on driver’s door B-pillar  .....237
Tire labeling  ....................................... 245
Tire load rating  .................................. 250
Tire ply composition and material
used  .................................................... 251
Tire pressure loss warning system  . 232
Tire repair kit see TIREFIT                                               
Tires  ........................................... 228, 353
Advanced Tire Pressure
Monitoring System (Advanced
TPMS)  ............................................ 233Index17212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 17 

V
Valet locking  ........................................ 85
Vehicle  
Battery  ........................................... 336
Care  ............................................... 260
Control system  .............................. 126
Identification Number (VIN)  ...........346
Locking/unlocking ........................... 76
Lowering (wheel change)  ...............328
Modifications and alterations,
Operating safety  .............................. 22
Towing  ........................................... 340
Unlocking/locking manually  ..........314
Vehicle dimensions
see Vehicle specification                          
Vehicle Identification Number
(VIN)  ................................................... 346
Vehicle jack see Jack                                                     
Vehicle level control
see AIRMATIC                                           
Vehicle lighting  .................................... 97
Vehicle loading  
Cargo tie-down rings ...................... 199
Instructions .................................... 197
Load limit  ....................................... 238
Roof rack  ....................................... 198
Split rear seat bench  .....................199
Terminology  ................................... 249
Vehicle maximum load on the tire  ... 252
Vehicle specification  
E 350  ............................................. 348
E 350 4MATIC ................................ 349
E 350 BlueTEC  ............................... 348
E 550  ............................................. 350
E 550 4MATIC ................................ 351
E 63 AMG  ...................................... 352
Vehicle status message memory  .... 139
Vehicle tool kit  .................................. 268
Vehicle washing see Vehicle care                                        
Vehicle weights
see Vehicle specification                          W
Warning sounds  
DISTRONIC PLUS  ........................... 151
Driver’s or passenger’s seat belt  .....52
Parking brake  ................................ 289
Parking Guidance ........................... 170
Parktronic system  ..........................168
Seat belt telltale  ............................ 307
Warranty coverage  ............................ 346
Washer and headlamp cleaning
system  ................................................ 367
Washer fluid  
Messages in the multifunction
display  ........................................... 294
Mixing ratio  .................................... 367
Refilling  .......................................... 227
Washing the vehicle  .......................... 260
Wear pattern (tires)  .......................... 244
Weights (vehicle) see Vehicle specification                          
Wheel  
Changing  ....................................... 323
Removing  ....................................... 326
Spare  ............................................. 323
Tightening torque ........................... 328
Wheels, sizes  ..................................... 353
Wheels, Tires and  .............................. 228
Window curtain air bags  ..................... 42
Windows see Power windows                                  
Windows, cleaning  ............................ 264
Windshield  
Cleaning wiper blades .................... 264
Washer fluid  ................................... 367
Wipers  ........................................... 104
Windshield wipers  
Replacing wiper blades  ..................322
Winter cover  .............................. 224, 252
Winter driving  
Instructions .................................... 253
Radiator cover  ............................... 252
Snow chains  .................................. 252
Tires ............................................... 252
Winter tires  ................................ 252, 353
Wood trims, cleaning  ........................ 266Index19212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 19