
Safety notes ..................................... 48
Telltale ............................... 29, 52, 307
Seat heating ......................................... 92
Seating capacity ................................ 238
Seats ..................................................... 87
Adjustment ...................................... 87
Drive-dynamic multicontour seat .....91
Easy-entry/exit feature ....................93
Heating ............................................ 92
Memory function .............................. 96
Messages in the multifunction
display ........................................... 293
Split rear seat bench .....................199
Ventilation ....................................... 92
Securing cargo
Cargo tie-down rings ...................... 199
Selective setting
see Key, SmartKey
Selector lever
see Gear selector lever
Self-test
BabySmart™ .................................... 47
OCS (Occupant Classification
System) ........................................... 46
Tele Aid .......................................... 208
Service
see Maintenance
Service, parts .................................... 346
Service and warranty information ..... 20
Service intervals see Maintenance System, Service
indicator message
Service life (tires) .............................. 242
Service menu ..................................... 138
Settings
Factory setting (KEYLESS-GO) .........79
Factory setting (SmartKey) ..............77
Memory function .............................. 96
Menu ............................................. 139
Selective setting (KEYLESS-GO) .......79
Selective setting (SmartKey) ............77
Shelf below rear window, cleaning .. 266
Side impact air bags ........................... 41
Side marker lamps
Cleaning lenses ............................. 262
Messages in the multifunction
display ........................................... 300Sidewall (tires) .................................. 251
SmartKey see Key, SmartKey
SmartKey with KEYLESS-GO
see Key, SmartKey
Snow chains ...................................... 252
Snow tires see Winter tires
Spare wheel ....................................... 353
Mounting ....................................... 323
Storage location ............................ 271
Speedometer ....................................... 28
Speed settings
Cruise control ................................ 147
DISTRONIC PLUS ........................... 155
Resume function ...................148, 156
SRS
Indicator lamp .................................. 29
SRS (Supplemental Restraint System)
Indicator lamp ......................... 36, 308
Messages in the multifunction
display ........................................... 290
Standing water, driving through ...... 257
Starter switch positions
KEYLESS-GO .................................... 86
SmartKey ......................................... 85
Starting difficulties (engine) ............ 110
Starting the engine ........................... 109
Steering column see Multifunction steering wheel,
Adjustment
Steering wheel
see Multifunction steering wheel
Steering wheel gearshift control ..... 122
Stolen Vehicle Recovery Services ... 212
Storage compartments ..................... 201
Storing tires ....................................... 243
Sunroof see Power tilt/sliding sunroof
Sunshade
Rear window .................................. 205
Sun visors .................................. 204, 205
Suspension tuning see AIRMATIC 16Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 16

T
Tachometer .................................. 28, 126
Overspeed range ........................... 126
Tail lamps
Cleaning lenses ............................. 262
Tar stains ........................................... 261
Technical data
Air conditioning refrigerant ............362
Brake fluid ..................................... 362
Capacities fuels, coolants,
lubricants etc. ................................ 359
Coolant .......................................... 365
Engine oil additives ........................362
Engine oils ..................................... 361
Fuel requirements .......................... 363
Gasoline additives .......................... 364
Identification labels .......................346
Premium unleaded gasoline ...........362
Rims and tires ................................ 353
Spare wheel ................................... 358
Vehicle specification E 350 ............ 348
Vehicle specification
E 350 4MATIC ................................ 349
Vehicle specification
E 350 BlueTEC ............................... 348
Vehicle specification E 550 ............ 350
Vehicle specification
E 550 4MATIC ................................ 351
Vehicle specification E 63 AMG .....352
Washer and headlamp cleaning
system ................................... 361, 367
Technical data (dimensions)
see Vehicle specification
Technical data (electrical system)
see Vehicle specification
Technical data (engine)
see Vehicle specification
Technical data (weights)
see Vehicle specification
Tele Aid ............................................... 207
Emergency calls ............................. 208
Information button .........................210
Initiating an emergency call
manually ........................................ 209
Messages in the multifunction
display ........................................... 290
Remote door lock .......................... 212Remote door unlock ......................211
Roadside Assistance button ..........210
Search & Send ............................... 211
SOS button .................................... 209
Stolen Vehicle Recovery Services ..212
System self-test ............................. 208
Telephone ............................................. 30
Answering/ending a call ................136
Hands-free microphone ...................33
Menu ............................................. 135
Operation ....................................... 135
Phone book .................................... 136
Redialing ........................................ 137
Temperature
Coolant .......................................... 125
Interior temperature ......................186
Outside .......................................... 126
Tether anchorage points
see Children in the vehicle
Through-loading feature ................... 198
Tie-down rings ................................... 199
Tightening torque
Wheels ........................................... 328
TIN (Tire Identification Number) ...... 251
Tire and Loading Information
placard ............................................... 237
Tire and loading terminology ........... 249
TIREFIT ............................................... 329
Tire Identification Number see TIN
Tire inflation pressure
Checking ........................................ 231
Important notes on ........................230
Label on the inside of fuel filler
flap ................................................ 230
Placard on driver’s door B-pillar .....237
Tire labeling ....................................... 245
Tire load rating .................................. 250
Tire ply composition and material
used .................................................... 251
Tire pressure loss warning system . 232
Tire repair kit see TIREFIT
Tires ........................................... 228, 353
Advanced Tire Pressure
Monitoring System (Advanced
TPMS) ............................................ 233Index17212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 17

V
Valet locking ........................................ 85
Vehicle
Battery ........................................... 336
Care ............................................... 260
Control system .............................. 126
Identification Number (VIN) ...........346
Locking/unlocking ........................... 76
Lowering (wheel change) ...............328
Modifications and alterations,
Operating safety .............................. 22
Towing ........................................... 340
Unlocking/locking manually ..........314
Vehicle dimensions
see Vehicle specification
Vehicle Identification Number
(VIN) ................................................... 346
Vehicle jack see Jack
Vehicle level control
see AIRMATIC
Vehicle lighting .................................... 97
Vehicle loading
Cargo tie-down rings ...................... 199
Instructions .................................... 197
Load limit ....................................... 238
Roof rack ....................................... 198
Split rear seat bench .....................199
Terminology ................................... 249
Vehicle maximum load on the tire ... 252
Vehicle specification
E 350 ............................................. 348
E 350 4MATIC ................................ 349
E 350 BlueTEC ............................... 348
E 550 ............................................. 350
E 550 4MATIC ................................ 351
E 63 AMG ...................................... 352
Vehicle status message memory .... 139
Vehicle tool kit .................................. 268
Vehicle washing see Vehicle care
Vehicle weights
see Vehicle specification W
Warning sounds
DISTRONIC PLUS ........................... 151
Driver’s or passenger’s seat belt .....52
Parking brake ................................ 289
Parking Guidance ........................... 170
Parktronic system ..........................168
Seat belt telltale ............................ 307
Warranty coverage ............................ 346
Washer and headlamp cleaning
system ................................................ 367
Washer fluid
Messages in the multifunction
display ........................................... 294
Mixing ratio .................................... 367
Refilling .......................................... 227
Washing the vehicle .......................... 260
Wear pattern (tires) .......................... 244
Weights (vehicle) see Vehicle specification
Wheel
Changing ....................................... 323
Removing ....................................... 326
Spare ............................................. 323
Tightening torque ........................... 328
Wheels, sizes ..................................... 353
Wheels, Tires and .............................. 228
Window curtain air bags ..................... 42
Windows see Power windows
Windows, cleaning ............................ 264
Windshield
Cleaning wiper blades .................... 264
Washer fluid ................................... 367
Wipers ........................................... 104
Windshield wipers
Replacing wiper blades ..................322
Winter cover .............................. 224, 252
Winter driving
Instructions .................................... 253
Radiator cover ............................... 252
Snow chains .................................. 252
Tires ............................................... 252
Winter tires ................................ 252, 353
Wood trims, cleaning ........................ 266Index19212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 19

contacting you in a timely manner should the
need arise.
If you sell your Mercedes, please leave all
literature with the vehicle to make it available
to the next operator.
If you bought this vehicle used, be sure to
send in the “Notice of Purchase of Used Car”
found in the Service and Warranty
Information Booklet, or call the Mercedes-
Benz Customer Assistance Center (in the
USA) at 1-800-FOR-MERCedes
(1-800-367-6372), or Customer Service (in
Canada) at 1-800-387-0100.
Operating your vehicle outside the
USA or Canada
If you plan to operate your vehicle in foreign
countries, please be aware that:
R Service facilities or replacement parts may
not be readily available.
R Unleaded gasoline for vehicles with
catalytic converters may not be available;
the use of leaded fuels will damage the
catalysts.
R Gasoline may have a considerably lower
octane rating, and improper fuel can cause
engine damage.
Certain Mercedes-Benz models are available
for delivery in Europe under our European
Delivery Program. For details, consult an
authorized Mercedes-Benz Center or write to:
In the USA:
Mercedes-Benz USA, LLC
European Delivery Department
One Mercedes Drive
Montvale, NJ 07645-0350
In Canada:
Mercedes-Benz Canada, Inc.
European Delivery Department
98 Vanderhoof Avenue
Toronto, Ontario M4G 4C9
Operating safetyGWarning!
Work improperly carried out on electronic
components and associated software could
cause them to cease functioning. Because the
vehicle’s electronic components are
interconnected, any modifications made may
produce an undesired effect on other
systems. Electronic malfunctions could
seriously impair the operating safety of your
vehicle.
Contact an authorized Mercedes-Benz Center
for repairs or modifications to electronic
components.
Other improper work or modifications on the
vehicle could also have a negative impact on
the operating safety of the vehicle.
Some safety systems only function while the
engine is running. You should therefore never
turn off the engine while driving.
GWarning!
Heavy blows against the vehicle underbody or
tires/wheels may cause serious damage and
impair the operating safety of your vehicle.
Such blows can be caused, for example, by
running over an obstacle, road debris or a
pothole. If you feel a sudden significant
vibration or ride disturbance, or you suspect
that damage to your vehicle as occurred:
R turn on your hazard warning flashers
R slow down carefully
R drive with caution to an area which is a safe
distance from the road
Inspect the vehicle underbody and tires/
wheels for possible damage. If the vehicle
appears unsafe, have it towed to the nearest
authorized Mercedes-Benz Center or other
qualified maintenance or repair facility for
further inspection or repairs.
22Introduction212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 22

Exterior view .......................................26
Cockpit .................................................27
Instrument cluster ..............................28
Multifunction steering wheel .............30
Center console ....................................32
Overhead control panel ......................33
Door control panel ..............................34
25At a glance212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 25

Exterior view
iThis Operator’s Manual describes all features, standard or optional, potentially available
for your vehicle at the time of purchase. Please be aware that your vehicle might not be
equipped with all features described in this manual.
FunctionPage:Trunk:Locking and unlocking76Opening and closing81Valet locking85;Rear window defroster191=Rear lamps318?Fuel filler flap220AExterior rear view mirrors95Parking position95BRoof:Power tilt/sliding sunroof192Panorama roof with power
tilt/sliding panel194
CWindshield:Wiping with washer fluid105FunctionPageCleaning264DDoors:Locking and unlocking76,
314
EWipers104Wiper blades, replacing322Wiper blades, cleaning264FHood223GFront lamps318HHeadlamp cleaning system102IFront towing eye341JTires and wheels228Rims and tires353KRear towing eye34126Exterior viewAt a glance
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CockpitFunctionPage:Steering wheel gearshift
control121
;Cruise control lever:Cruise control146DISTRONIC PLUS149=Instrument cluster125?Multifunction steering
wheel126
AHornBGear selector lever115CFront Parktronic warning
indicators 167
DOverhead control panel33EGlove box201FCenter console32GStarter switch85FunctionPageKEYLESS-GO start/stop
button86
HSteering wheel adjustment
stalk93
ICombination switch:Turn signals100Wipers104High beam100JParking brake pedal113KOn-board diagnostics
(OBD) socket
LHood lock release223MParking brake release113NDoor control panel34OExterior lamp switch97PNight View Assist Plus172Cockpit27At a glance212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 27Z

FunctionPageNLow-beam headlamp
indicator lamp 97
OESC SPORT warning lamp67PFuel tank reserve warning
lamp310Multifunction steering wheelFunctionPage:Multifunction display128;Press button W or X
to set the volume.134
Press button ~:to end a call136to reject an incoming call136Press button 6:to answer a call136to dial2136to redial2137Press button 8 to mute.=Press button ? to
activate the Voice Control
System3.
2Function only available in telephone menu.3Function only available in vehicles with Voice Control System.
30Multifunction steering wheelAt a glance
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