
ESC (Electronic Stability Control) ...... 65
ETS/4-ETS  ....................................... 65
Messages in the multifunction
display  ........................... 288, 289, 290
Warning lamp ................................. 309
ETD (Emergency Tensioning
Device)  ................................................. 52
Safety guidelines  ............................. 39
ETS/4-ETS (Electronic Traction
System)  ................................................ 65
Express operation  
Panorama roof  ............................... 195
Power windows  .............................. 105
Tilt/sliding sunroof  ........................192
Exterior lamp switch  ........................... 97
Exterior rear view mirrors  .................. 95
Parking position  ............................... 95
Exterior view of vehicle  ...................... 26
F
Fastening the seat belts  ..................... 50
First aid kit  ......................................... 268
Flat tire  ............................................... 323
Lowering the vehicle  ......................328
Mounting the spare wheel  .............323
Preparing the vehicle  .....................323
Spare wheel ........................... 323, 358
TIREFIT (tire repair kit)  ...................329
Floormats  ........................................... 217
Fluids  
Automatic transmission fluid  .........360
Brake fluid  ..................................... 361
Capacities  ...................................... 359
Engine coolant  ............................... 361
Engine oil  ....................................... 360
Power steering fluid  .......................360
Washer and headlamp cleaning
system  ........................................... 361
Fog lamps  ............................................. 99
Messages in the multifunction
display  ................................... 300, 302
Four-wheel drive
see All-wheel drive (4MATIC)                    
Front air bags
see Air bags                                              
Front axle oil  ...................................... 360
Front lamps
see Headlamps                                         
Front passenger front air bag  ............ 40
Messages in the multifunction
display  ........................................... 276
Front passenger front air bag off
indicator lamp (Canada only)  ..... 46, 313
Front passenger front air bag off
indicator lamp (USA only)  .......... 43, 314
Fuel  ..................................................... 220
Additives  ........................................ 364
Capacity, fuel tank  .........................361
Diesel fuel  ...................................... 363
Drive sensibly–safe fuel  .................254
Fuel consumption statistics  ...........130
Fuel filler flap and cap  ...................222
Fuel tank reserve warning lamp  .....310
Premium unleaded gasoline  ...........362
Refueling ........................................ 220
Requirements  ................................ 363
Fuel filler flap  ..................................... 222
Opening manually  ..........................316
Fuel gauge  ......................................... 126
Fuels, coolants, lubricants etc.  ........ 359
Fuel system, bleeding (diesel
engine)  ............................................... 333
Fuel tank  
Capacity  ........................................ 361
Fuel filler flap and cap  ...................222
Refueling ........................................ 220
Fuses  .................................................. 343
G
Garage door opener  .................... 33, 212
Gasoline see Fuel                                                     
GAWR (Gross Axle Weight Rating)  ... 250
Gear range  ......................................... 120
Indicator  ........................................ 120
Limiting  .......................................... 122
Shifting into optimal  ......................122
Gear selector lever  ............................ 115
Cleaning ......................................... 265
Gearshift pattern  ........................... 115
Shifting procedure  .........................118
Transmission position indicator  .....118
Transmission positions  ..................118
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SRS .......................................... 36, 308
Turn signals  ..................................... 29
Lane Keeping Assist  .......................... 177
Messages in the multifunction
display  ........................................... 283
Switching on or off ......................... 138
LATCH-type child seat anchors (ISOFIX)
see Children in the vehicle                        
License plate lamps  
Messages in the multifunction
display  ........................................... 301
Light alloy wheels, cleaning  ............. 265
Lighter see Cigarette lighter                                 
Lighting  ................................................ 97
Daytime running lamp mode  ............98
Exterior  ............................................ 97
Interior  ........................................... 103
Limp-home mode  .............................. 124
Load index (tires)  ...................... 246, 250
Loading see Vehicle loading                                   
Locator lighting  ................................. 142
Locking the vehicle  
KEYLESS-GO  .................................... 77
Manually  ........................................ 315
SmartKey  ......................................... 76
Loss of  
Key  .................................................. 79
Service and Warranty Information
booklet  .......................................... 346
Low-beam headlamps  ......................... 98
Exterior lamp switch  ........................97
Indicator lamp .................................. 30
Replacing bulbs  ............................. 319
Switching on  .................................... 98
Lubricants  .......................................... 359
Lumbar support  ................................... 89
M
Maintenance  ........................................ 21
Maintenance System  
Service indicator display  ................259
Service indicator message  .............258
Service term exceeded  ..................259
Manual headlamp mode (Low-
beam headlamps)  ................................ 98
Manual shift program  ....................... 122
Maximum engine speed see Vehicle specification                          
Maximum loaded vehicle weight  ..... 250
Maximum load rating (tires)  ............. 250
Maximum permissible tire
inflation pressure  .............................. 251
Mechanical key see Key, Mechanical                                 
Media interface  ................................. 201
Memory function  ................................. 96
Menus see Control system menus                       
Minispare wheel
see Spare wheel                                        
Mirrors  .................................................. 94
Auto-dimming rear view mirrors ....... 95
Exterior rear view mirror parking
position  ............................................ 95
Exterior rear view mirrors  ................95
Interior rear view mirror  ...................94
Memory function .............................. 96
Vanity mirror  .................................. 205
MOExtended system  ......................... 329
MOExtended tires  ..................... 329, 353
MON (Motor Octane Number)  .......... 363
Motor Octane Number see MON                                                   
Multifunction display  ........................ 128
Symbol messages  ..........................287
Text messages  ............................... 274
Vehicle status messages  ...............272
Multifunction display messages  
ABS  ....................................... 288, 289
Active headlamps  .......................... 299
Advanced TPMS  ............................. 285
Air bags  ......................................... 276
Air filter .......................................... 299
AIRMATIC  ...................................... 292
Alternator  .............................. 284, 297
ATTENTION ASSIST  ........................292
Automatic
transmission  .......................... 283, 284
Backrests ....................................... 293
Battery  ................................... 284, 297
Blind Spot Assist ............................ 281
Brake fluid  ..................................... 28912Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 12 

Safety notes ..................................... 48
Telltale  ............................... 29, 52, 307
Seat heating  ......................................... 92
Seating capacity  ................................ 238
Seats  ..................................................... 87
Adjustment  ...................................... 87
Drive-dynamic multicontour seat  .....91
Easy-entry/exit feature  ....................93
Heating  ............................................ 92
Memory function .............................. 96
Messages in the multifunction
display  ........................................... 293
Split rear seat bench  .....................199
Ventilation  ....................................... 92
Securing cargo  
Cargo tie-down rings ...................... 199
Selective setting
see Key, SmartKey                                    
Selector lever
see Gear selector lever                             
Self-test  
BabySmart™  .................................... 47
OCS (Occupant Classification
System)  ........................................... 46
Tele Aid  .......................................... 208
Service
see Maintenance                                       
Service, parts  .................................... 346
Service and warranty information  ..... 20
Service intervals see Maintenance System, Service
indicator message                                     
Service life (tires)  .............................. 242
Service menu  ..................................... 138
Settings  
Factory setting (KEYLESS-GO)  .........79
Factory setting (SmartKey)  ..............77
Memory function .............................. 96
Menu  ............................................. 139
Selective setting (KEYLESS-GO)  .......79
Selective setting (SmartKey)  ............77
Shelf below rear window, cleaning  .. 266
Side impact air bags  ........................... 41
Side marker lamps  
Cleaning lenses  ............................. 262
Messages in the multifunction
display  ........................................... 300Sidewall (tires) .................................. 251
SmartKey see Key, SmartKey                                    
SmartKey with KEYLESS-GO
see Key, SmartKey                                    
Snow chains  ...................................... 252
Snow tires see Winter tires                                         
Spare wheel  ....................................... 353
Mounting  ....................................... 323
Storage location  ............................ 271
Speedometer  ....................................... 28
Speed settings  
Cruise control  ................................ 147
DISTRONIC PLUS  ........................... 155
Resume function  ...................148, 156
SRS  
Indicator lamp .................................. 29
SRS (Supplemental Restraint System)  
Indicator lamp  ......................... 36, 308
Messages in the multifunction
display  ........................................... 290
Standing water, driving through  ...... 257
Starter switch positions  
KEYLESS-GO  .................................... 86
SmartKey  ......................................... 85
Starting difficulties (engine)  ............ 110
Starting the engine  ........................... 109
Steering column see Multifunction steering wheel,
Adjustment                                               
Steering wheel
see Multifunction steering wheel              
Steering wheel gearshift control  ..... 122
Stolen Vehicle Recovery Services  ... 212
Storage compartments  ..................... 201
Storing tires  ....................................... 243
Sunroof see Power tilt/sliding sunroof                  
Sunshade  
Rear window  .................................. 205
Sun visors  .................................. 204, 205
Suspension tuning see AIRMATIC                                           16Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 16 

T
Tachometer  .................................. 28, 126
Overspeed range  ........................... 126
Tail lamps  
Cleaning lenses  ............................. 262
Tar stains  ........................................... 261
Technical data  
Air conditioning refrigerant  ............362
Brake fluid  ..................................... 362
Capacities fuels, coolants,
lubricants etc.  ................................ 359
Coolant  .......................................... 365
Engine oil additives  ........................362
Engine oils  ..................................... 361
Fuel requirements .......................... 363
Gasoline additives .......................... 364
Identification labels  .......................346
Premium unleaded gasoline  ...........362
Rims and tires  ................................ 353
Spare wheel  ................................... 358
Vehicle specification E 350 ............ 348
Vehicle specification
E 350 4MATIC ................................ 349
Vehicle specification
E 350 BlueTEC  ............................... 348
Vehicle specification E 550 ............ 350
Vehicle specification
E 550 4MATIC ................................ 351
Vehicle specification E 63 AMG  .....352
Washer and headlamp cleaning
system  ................................... 361, 367
Technical data (dimensions)
see Vehicle specification                          
Technical data (electrical system)
see Vehicle specification                          
Technical data (engine)
see Vehicle specification                          
Technical data (weights)
see Vehicle specification                          
Tele Aid  ............................................... 207
Emergency calls  ............................. 208
Information button  .........................210
Initiating an emergency call
manually  ........................................ 209
Messages in the multifunction
display  ........................................... 290
Remote door lock  .......................... 212Remote door unlock  ......................211
Roadside Assistance button  ..........210
Search & Send  ............................... 211
SOS button  .................................... 209
Stolen Vehicle Recovery Services  ..212
System self-test  ............................. 208
Telephone  ............................................. 30
Answering/ending a call  ................136
Hands-free microphone  ...................33
Menu  ............................................. 135
Operation ....................................... 135
Phone book .................................... 136
Redialing  ........................................ 137
Temperature  
Coolant  .......................................... 125
Interior temperature  ......................186
Outside  .......................................... 126
Tether anchorage points
see Children in the vehicle                        
Through-loading feature  ................... 198
Tie-down rings  ................................... 199
Tightening torque  
Wheels  ........................................... 328
TIN (Tire Identification Number)  ...... 251
Tire and Loading Information
placard  ............................................... 237
Tire and loading terminology  ........... 249
TIREFIT  ............................................... 329
Tire Identification Number see TIN                                                      
Tire inflation pressure  
Checking ........................................ 231
Important notes on  ........................230
Label on the inside of fuel filler
flap  ................................................ 230
Placard on driver’s door B-pillar  .....237
Tire labeling  ....................................... 245
Tire load rating  .................................. 250
Tire ply composition and material
used  .................................................... 251
Tire pressure loss warning system  . 232
Tire repair kit see TIREFIT                                               
Tires  ........................................... 228, 353
Advanced Tire Pressure
Monitoring System (Advanced
TPMS)  ............................................ 233Index17212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 17 

V
Valet locking  ........................................ 85
Vehicle  
Battery  ........................................... 336
Care  ............................................... 260
Control system  .............................. 126
Identification Number (VIN)  ...........346
Locking/unlocking ........................... 76
Lowering (wheel change)  ...............328
Modifications and alterations,
Operating safety  .............................. 22
Towing  ........................................... 340
Unlocking/locking manually  ..........314
Vehicle dimensions
see Vehicle specification                          
Vehicle Identification Number
(VIN)  ................................................... 346
Vehicle jack see Jack                                                     
Vehicle level control
see AIRMATIC                                           
Vehicle lighting  .................................... 97
Vehicle loading  
Cargo tie-down rings ...................... 199
Instructions .................................... 197
Load limit  ....................................... 238
Roof rack  ....................................... 198
Split rear seat bench  .....................199
Terminology  ................................... 249
Vehicle maximum load on the tire  ... 252
Vehicle specification  
E 350  ............................................. 348
E 350 4MATIC ................................ 349
E 350 BlueTEC  ............................... 348
E 550  ............................................. 350
E 550 4MATIC ................................ 351
E 63 AMG  ...................................... 352
Vehicle status message memory  .... 139
Vehicle tool kit  .................................. 268
Vehicle washing see Vehicle care                                        
Vehicle weights
see Vehicle specification                          W
Warning sounds  
DISTRONIC PLUS  ........................... 151
Driver’s or passenger’s seat belt  .....52
Parking brake  ................................ 289
Parking Guidance ........................... 170
Parktronic system  ..........................168
Seat belt telltale  ............................ 307
Warranty coverage  ............................ 346
Washer and headlamp cleaning
system  ................................................ 367
Washer fluid  
Messages in the multifunction
display  ........................................... 294
Mixing ratio  .................................... 367
Refilling  .......................................... 227
Washing the vehicle  .......................... 260
Wear pattern (tires)  .......................... 244
Weights (vehicle) see Vehicle specification                          
Wheel  
Changing  ....................................... 323
Removing  ....................................... 326
Spare  ............................................. 323
Tightening torque ........................... 328
Wheels, sizes  ..................................... 353
Wheels, Tires and  .............................. 228
Window curtain air bags  ..................... 42
Windows see Power windows                                  
Windows, cleaning  ............................ 264
Windshield  
Cleaning wiper blades .................... 264
Washer fluid  ................................... 367
Wipers  ........................................... 104
Windshield wipers  
Replacing wiper blades  ..................322
Winter cover  .............................. 224, 252
Winter driving  
Instructions .................................... 253
Radiator cover  ............................... 252
Snow chains  .................................. 252
Tires ............................................... 252
Winter tires  ................................ 252, 353
Wood trims, cleaning  ........................ 266Index19212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 19 

Switching the ESC off or on 
(except E 63 AMG)
GWarning!
The ESC should not be switched off during
normal driving other than in the
circumstances described below. Disabling
the system will reduce vehicle stability in
driving maneuvers.
Do not switch off the ESC when a spare wheel
is mounted.
To improve the vehicle’s traction, switch off
the ESC. This allows the drive wheels to spin
and thus cut into surfaces for better grip, for
example
Rwhen driving with snow chains
Rin deep snow
Rin sand or gravel
GWarning!
Switch on the ESC immediately if the
aforementioned circumstances do not apply
anymore. Otherwise the ESC will not stabilize
the vehicle when it is starting to skid or a
wheel is spinning.
When you switch off the ESC,
Rthe ESC does not stabilize the vehicle
Rthe engine output is not limited, which
allows the drive wheels to spin and thus cut
into surfaces for better grip
Rthe ETS/4-ETS will still apply the brakes to
a spinning wheel
Rthe ESC continues to operate when you are
braking
Rthe cruise control or the DISTRONIC PLUS
cannot be activated
Rthe cruise control or the DISTRONIC PLUS
switch off if activated
iWhen the ESC is switched off and one or
more drive wheels are spinning, the ESC
warning lamp ä in the instrument
cluster flashes. However, the ESC will then
not stabilize the vehicle.
XSwitching off: With the engine running,
press ESC switch : until the ESC OFF
warning lamp å in the instrument
cluster comes on.
The ESC is switched off.
GWarning!
When the ESC OFF warning lamp å is on,
the ESC is switched off.
When the ESC warning lamp ä and the
ESC OFF warning lamp å are on
continuously, the ESC is not operational due
to a malfunction.
When the ESC is switched off or not
operational, vehicle stability in standard
driving maneuvers is reduced.
Adapt your speed and driving to the prevailing
road conditions and to the non-operating
status of the ESC.
! Avoid spinning of a drive wheel for an
extended period with the ESC switched off.
This may cause serious damage to the
drivetrain which is not covered by the
Mercedes-Benz Limited Warranty.
XSwitching on: Press ESC switch : until
the ESC OFF warning lamp å in the
instrument cluster goes out.
You are now again in normal driving mode
with the ESC switched on.
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E 63 AMG
Switching ESC SPORT on or off
GWarning!
ESC SPORT should not be switched on during
normal driving.
Switching ESC SPORT on will result in the
following:
Rno restriction to engine torque
Rsystem-supported traction control is
limited
ESC SPORT is designed for driving on closed
tracks when the vehicle’s natural oversteer
and understeer characteristics are desired
and requires a highly skilled and experienced
driver able to handle these critical driving
situations.
You could lose control of your vehicle and
cause an accident.
Please be aware of these limits when you
switch on ESC SPORT.
Do not switch on ESC SPORT when a spare
wheel is mounted.
To improve the vehicle’s traction, switch on
ESC SPORT. This allows the drive wheels to
spin and thus cut into surfaces for better grip,
for example
Rwhen driving with snow chains
Rin deep snow
Rin sand or gravel
GWarning!
Switch off ESC SPORT and switch on the ESC
immediately if the aforementioned
circumstances do not apply anymore.
Otherwise ESC will only stabilize the vehicle
to a limited extent when it is starting to skid
or a wheel is spinning.
When you switch on ESC SPORT
Rthe ESC stabilizes the vehicle only to a
limited extent
Rthe engine output is limited, but only to the
extent that allows the drive wheels to spin
and thus cut into surfaces for better grip
Rthe ETS will still apply the brakes to a
spinning wheel
Rthe ESC continues to operate when you are
braking hard
Rthe cruise control or the DISTRONIC PLUS
cannot be activated
Rthe cruise control or the DISTRONIC PLUS
switch off if activated
iWhen ESC SPORT is switched on and one
or more drive wheels are spinning, the ESC
warning lamp ä in the instrument
cluster flashes. However, the ESC will then
stabilize the vehicle only to a limited extent.
XSwitching on: With the engine running,
press ESC SPORT switch : briefly.
The ESC SPORT warning lamp ì in the
instrument cluster comes on. The message
ESC-SPORT appears in the multifunction
display.
XSwitching off: With the engine running,
press ESC SPORT switch : briefly.
The ESC SPORT warning lamp ì in the
instrument cluster goes out. The message
ESC-ON appears in the multifunction
display.
Driving safety systems67Safety and security212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 67Z   

ESC SPORT switches off automatically when
you turn off the engine. When starting the
engine, the ESC is activated automatically.
Switching the ESC off or on
GWarning!
The ESC should not be switched off during
normal driving.
Disabling of the system will result in the
following:
Rno restriction to engine torque
Rloss of system-supported traction control
“ESC OFF” is designed for driving on closed
tracks when the vehicle’s natural oversteer
and understeer characteristics are desired
and requires a highly skilled and experienced
driver able to handle these critical driving
situations.
You could lose control of your vehicle and
cause an accident.
Please be aware of these limits when you
switch off the ESC.
Do not switch off the ESC when a spare wheel
is mounted.
To improve the vehicle’s traction, switch off
the ESC. This allows the drive wheels to spin
and thus cut into surfaces for better grip, for
example
Rwhen driving with snow chains
Rin deep snow
Rin sand or gravel
GWarning!
Switch on the ESC immediately if the
aforementioned circumstances do not apply
anymore. Otherwise the ESC will not stabilize
the vehicle when it is starting to skid or a
wheel is spinning.
When you switch off the ESC,
Rthe ESC will not stabilize the vehicle
Rthe engine output is not limited, which
allows the drive wheels to spin and thus cut
into surfaces for better grip
Rthe ETS will still apply the brakes to a
spinning wheel
Rthe ESC continues to operate when you are
braking hard
Rthe PRE-SAFE® system is not available,
even when you are braking hard supported
by the ESC
Rthe PRE-SAFE® Brake is not available, even
when you are braking hard supported by
the ESC
Rthe cruise control or the DISTRONIC PLUS
cannot be activated
Rthe cruise control or the DISTRONIC PLUS
switch off if activated
iWhen ESC is switched off and one or more
drive wheels are spinning, the ESC warning
lamp ä in the instrument cluster does
not flash. The ESC will not stabilize the
vehicle.
XSwitching off: With the engine running,
press ESC switch : until the ESC OFF
warning lamp å in the instrument
cluster comes on.
The message ESC-OFF appears in the
multifunction display.
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