2010 MERCEDES-BENZ E350 Switch

! Never refuel vehicles with gasoline engine
with diesel fuel. Never refuel vehicles with
diesel engine with gasoline. Even small
amounts of incorrect fuel will damage the
fuel system and engine. Damage resulting
from the use of non-approved fuels or fuel
additives or resulting from mixing gasoline
with diesel fuel or vice versa is not covered
by the Mercedes-Benz Limited Warranty.
! If you have accidentally filled the tank
with incorrect or non-approved fuel, do not
switch on the ignition. Otherwise the
incorrect or non-approved fuel will get into
the fuel lines. The fuel system must be
drained completely. Contact an authorized
Mercedes-Benz Center to have the fuel
system drained completely.
! Gasoline engine:
To prevent damage to the catalytic
converters, only use premium unleaded
gasoline in this vehicle.
Any noticeable irregularities in engine
operation should be repaired promptly.
Otherwise, excessive unburned fuel may
reach the catalytic converter, causing it to
overheat and potentially start a fire.
! Diesel engine:
When filling the diesel fuel tank using fuel
containers, place a filling filter, a suede
cloth or a clean flannel cloth as a filter.
Otherwise, particles from the fuel container
could clog the fuel lines and/or the diesel
injection system.
! Diesel engine:
The engine is more susceptible to wear and
damage if you use
R marine diesel fuel
R heating oil
R additives
The exhaust aftertreatment device will be
seriously damaged if you use any other
diesel fuel than ULTRA-LOW SULFURHIGHWAY DIESEL FUEL (ULSD, 15 ppm
SULFUR MAXIMUM).
The use of such non-approved fuels and/or
special additives is not covered by the
Mercedes-Benz Limited Warranty.
i Gasoline engine:
Only use premium unleaded gasoline with
a minimum Posted Octane Rating of 91
(average of 96 RON/86 MON).
Information on gasoline quality can
normally be found on the fuel pump. Please
contact gas station personnel in case
labels on the pump cannot be found.
For more information on gasoline, see
“Premium unleaded gasoline (gasoline
engine)” ( Y page 362), see “Fuel
requirements” ( Y page 363), or contact an
authorized Mercedes-Benz Center, or visit
www.mbusa.com (USA only).
i Diesel engine:
Only use commercially available vehicular
ULTRA-LOW SULFUR HIGHWAY DIESEL
FUEL (ULSD, 15 ppm SULFUR MAXIMUM).
Information on diesel quality can normally
be found on the fuel pump. Please contact
gas station personnel in case labels on the
pump cannot be found.
For more information on diesel fuels, see
“Fuel requirements” ( Y page 363), or
contact an authorized Mercedes-Benz
Center, or visit www.mbusa.com (USA
only).
i Diesel engine:
If you have driven the vehicle until the tank
is empty, the fuel system needs to be bled
( Y page 333).
Locking/unlocking the vehicle with the
SmartKey or KEYLESS-GO automatically
locks/unlocks the fuel filler flap.
i In case the central locking system does
not release the fuel filler flap, see “Fuel filler
flap” ( Y page 316).At the gas station221Operation212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 221Z

The fuel filler flap is located on the right-hand
side of the vehicle towards the rear.
XTurn off the engine.
iLeaving the engine running and the fuel
filler cap open can cause the yellow engine
malfunction indicator lamp ; to
illuminate.
For more information, see also “Practical
hints” (Y page 310).
XRemove the SmartKey from the starter
switch.
KEYLESS-GO: Open the driver’s door. This
puts the starter switch in position 0, same
as with the SmartKey removed from the
starter switch. The driver’s door then can
be closed again.
XOpening: Press fuel filler flap : at the
point indicated by the arrow.
XTurn fuel filler cap ; counterclockwise.XTake off fuel filler cap ;.
! The fuel filler cap is tethered to the fuel
filler neck. Do not drop the cap. It could
damage the vehicle paint finish.
XPlace fuel filler cap ; in direction of arrow
into holder =.
XFully insert filler nozzle unit and refuel.XOnly fill your tank until the filler nozzle unit
cuts out – do not top off or overfill.
XClosing: Turn fuel filler cap ; clockwise
until it audibly engages.
iClose the fuel filler flap before locking the
vehicle. Otherwise the flap locking pin will
prevent closing the fuel filler flap.
XClose fuel filler flap :.
Low outside temperatures (diesel
engine)
! Do not fill the tank with gasoline. Do not
blend diesel fuel with gasoline or kerosene.
The fuel system and engine will otherwise
be damaged, which is not covered by the
Mercedes-Benz Limited Warranty.
To prevent malfunctions, diesel fuel with
improved cold flow characteristics is offered
in the winter months. Check with your fuel
retailer.
Check regularly and before a long trip
For information on quantities and
requirements of operating agents, see “Fuels,
coolants, lubricants, etc.” (Y page 359).
Check the following:
REngine oil level (Y page 224)
RTire inflation pressure (Y page 231)
RCoolant level (Y page 226)
RVehicle lighting (Y page 318)
RWasher system and headlamp cleaning
system (Y page 227)
RBrake fluid (Y page 227)
222At the gas stationOperation
212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 222

Engine compartment
Hood
GWarning!
Do not pull the release lever while the vehicle
is in motion. Otherwise the hood could be
forced open by passing air flow.
This could cause the hood to come loose and
injure you and/or others.
Opening
GWarning!
Do not open the hood when the engine is
overheated. You could be seriously injured.
Observe the coolant temperature gauge to
determine whether the engine may be
overheated. If you see flames or smoke
coming from the engine compartment, move
away from the vehicle. Wait until the engine
has cooled. If necessary, call the fire
department.
GWarning!
You could be injured when the hood is open –
even when the engine is turned off.
Parts of the engine can become very hot. To
prevent burns, let the engine cool completely
before touching any components on the
vehicle. Comply with all relevant safety
precautions.
GWarning!
To help prevent personal injury, stay clear of
moving parts when the hood is open and the
engine is running.
The radiator fan may continue to run for
approximately 30 seconds or may even
restart after the engine has been turned off.
Stay clear of fan blades.
GWarning!
Vehicles with gasoline engine:
The engine is equipped with a transistorized
ignition system. Because of the high voltage
it is dangerous to touch any components
(ignition coils, spark plug sockets, diagnostic
socket) of the ignition system
Rwith the engine running
Rwhile starting the engine
Rwhen the ignition is switched on and the
engine is turned manually
GWarning!
Vehicles with diesel engine:
The engine is equipped with a high-voltage
electronic control unit for the injection
system. Because of the high voltage it is
dangerous to touch any components of the
injection system (injectors, electrical wires)
Rwith the engine running
Rwhile starting the engine
Rwhen the ignition is switched on
XPull hood lock release lever :.
The hood is unlocked.
! Never open the hood if the wiper arms are
folded forward away from the windshield.
Otherwise the windshield wipers or the
hood could be damaged.
Engine compartment223Operation212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 223Z

applying the brakes and avoiding abrupt
steering maneuvers.
Restarting the tire pressure loss warning
system
The tire pressure loss warning system must
be restarted in the following situations:
R after you have changed the tire inflation
pressure
R after you have replaced the wheels or tires
R after you have installed new wheels or tiresXUsing the Tire and Loading Information
placard on the driver’s door B-pillar or, if
available, the tire inflation pressure label on
the inside of the fuel filler flap, make sure
the tire inflation pressure of all four tires is
correct.GWarning!
The tire pressure loss warning system can
only warn you in a reliable manner if you have
set the correct tire inflation pressures for
each tire.
If an incorrect tire inflation pressure was set,
the system will monitor the pressure
according to the incorrect value.
XSwitch on the ignition.XPress button = or ; on the
multifunction steering wheel to select the
Serv. menu ( Y page 138).XPress button 9 or : on the
multifunction steering wheel to select
Tire Pressure .XPress button a on the multifunction
steering wheel to confirm.
The following message appears in the
multifunction display:
Run Flat Indicator
Active
Press 'OK' to RestartXPress button a.
The following message will appear in the
multifunction display:
Tire PressureNow OK?
Cancel
YesXIf you wish to confirm: Press button
9 or : to select Yes.XPress button a.
The following message will appear in the
multifunction display:
Run Flat
Indicator
Restarted
After a certain “learning phase”, the tire
pressure loss warning system checks the
set pressure values for all four tires.XIf you wish to cancel: Press button 9
or : to select Cancel.XPress button a to confirm.
The previous settings remain unchanged.
Advanced Tire Pressure Monitoring
System (Advanced TPMS)
Your vehicle is equipped with the Advanced
Tire Pressure Monitoring System (Advanced
TPMS). It measures the tire inflation pressure
in the vehicle’s tires and issues warnings in
case of pressure loss in one or more of the
tires.
The TPMS is equipped with a combination low
tire pressure/TPMS malfunction telltale
(USA) or a low tire pressure telltale (Canada)
in the instrument cluster. Depending on how
the telltale illuminates, it indicates a low tire
pressure condition or a malfunction in the
TPMS system itself:
R If the telltale illuminates continuously, one
or more of your tires is significantly
underinflated. There is no malfunction in
the TPMS.
R USA only: If the telltale flashes for 60
seconds and then stays illuminated, the
TPMS system itself is not operating
properly.
The TPMS only functions on wheels that are
equipped with the proper electronic sensors.
Tires and wheels233Operation212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 233Z

pressure displayed by the control system
apply to sea level. In high-altitude
locations, the reading on a tire pressure
gauge will be higher than the reading issued
by the vehicle’s control system. Do not
reduce the tire inflation pressure under
such circumstances.
XSwitch on the ignition.XPress button = or ; on the
multifunction steering wheel to select the
Serv. menu (Y page 138).
XPress button 9 or : to select Tire
Pressure.
XPress button a.
The current inflation pressure for each tire
appears in the multifunction display.
Example illustration
When the vehicle has been parked for longer
than 20 minutes, the message Tire
pressures will be displayed after
driving a few minutes appears in the
multifunction display.
The TPMS recognizes new wheels or sensors
automatically after the learn-in phase. As long
as the tire inflation pressure values cannot be
allocated to the individual wheels, the
message Tire Pressure Monitor Active
appears. Despite this message, the tire
inflation pressure values are monitored
already.
iWith a spare wheel mounted, the system
may still indicate the tire inflation pressure
of the removed road wheel for some
minutes. If this happens, keep in mind that
the indicated value where the spare wheel
is mounted does not reflect the actual
spare tire inflation pressure.
iOperating radio transmission equipment
(e.g. wireless headsets, two-way radios) in
or near the vehicle could cause the TPMS
to malfunction.
iUSA only:
This device complies with Part 15 of the
FCC Rules. Operation is subject to the
following two conditions:
1. This device may not cause harmful
interference, and
2. this device must accept any
interference received, including
interference that may cause undesired.
Any unauthorized modification to this
device could void the user’s authority to
operate the equipment.
iCanada only:
This device complies with RSS-210 of
Industry Canada. Operation is subject to
the following two conditions:
1.This device may not cause interference,
and
2. this device must accept any
interference received, including
interference that may cause undesired
operation of the device.
Any unauthorized modification to this
device could void the user’s authority to
operate the equipment.
Tire inflation pressure warnings
If the system detects a significant loss of tire
inflation pressure in one or more than one
tire, a message appears in the multifunction
display. In addition, an acoustic warning
sounds and the low tire pressure telltale in the
instrument cluster comes on.
Tires and wheels235Operation212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 235Z

Example illustration
The respective tire is indicated by a red
rectangle.
Restarting Advanced TPMS
GWarning!
It is the driver’s responsibility to set the tire
inflation pressure to the recommended cold
tire inflation pressure. Underinflated tires
affect the ability to steer or brake the vehicle.
You might lose control over the vehicle.
When you restart the TPMS, the system sets
new reference values for each tire.
The TPMS must be restarted when you have
adjusted the tire inflation pressure to a new
level (e.g. because of different load or driving
conditions). The TPMS is then recalibrated to
the current tire inflation pressures.
iCanada only:
The TPMS usually recognizes tire pressure
adjustments and sets new reference values
automatically. You can, however, restart
the TPMS manually as described.
Restart the TPMS after adjusting the tire
inflation pressure to the inflation pressure
recommended for the vehicle operating
condition. Tire inflation pressure should only
be adjusted on cold tires. Observe the
recommended tire inflation pressure on the
Tire and Loading Information placard on the
driver’s door B-pillar. Some vehicles may have
supplemental tire inflation pressure
information for driving at high speeds or for
vehicle loads less than the maximum loaded
vehicle condition. If such information is
provided, it can be found on the inside of the
fuel filler flap.
XUsing the Tire and Loading Information
placard on the driver’s door B-pillar
(Y page 237) or the supplemental tire
inflation pressure information on the inside
of the fuel filler flap, make sure the tire
inflation pressure of all four tires is correct.
XSwitch on the ignition.XPress button = or ; on the
multifunction steering wheel to select the
Serv. menu.
XPress button 9 or : on the
multifunction steering wheel to select
Tire Pressure.
XPress button a.
The current inflation pressure for each tire
appears in the multifunction display or the
following message appears in the
multifunction display:
Tire pressures
will be displayed
after driving
a few minutes
XPress button :.
The following message appears in the
multifunction display:
Use Current
Pressures As New
Reference Values
Press 'OK' to Confirm
XPress button a.
The following message appears in the
multifunction display:
Tire Press. Monitor
Restarted
After driving a few minutes the system
verifies that the current tire inflation
pressures are within the system’s specified
range. Afterwards the current tire inflation
pressures are accepted as reference values
and then monitored.
XIf you wish to cancel: Press button %.
or
XPress button 9 to exit the menu screen.
iWhen the wheel positions have been
changed, the inflation pressure of a tire
236Tires and wheelsOperation
212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 236

control. Other settings may result in
damage to your vehicle.
! Some tire sizes do not leave adequate
clearance for snow chains. To help avoid
serious damage to your vehicle or tires,
make sure the use of snow chains is
permissible as specified in the “Technical
data” section of this Operator’s Manual.
Snow chains should only be driven on snow-
covered roads at speeds not to exceed
30 mph (50 km/h). Remove chains as soon
as possible when driving on roads without
snow.
Observe the following guidelines when using
snow chains:
R Use of snow chains is not permissible with
all wheel/tire combinations ( Y page 353).
R Use snow chains in pairs and on rear
wheels only. Follow the manufacturer’s
mounting instructions.
! If snow chains are mounted to the front
wheels, they may scrape against the body
or axle components. The tires or the vehicle
could be damaged as a result.
R Only use snow chains that are approved by
Mercedes-Benz. Any authorized Mercedes-
Benz Center will be glad to advise you on
this subject.
R Use of snow chains may be prohibited
depending on location. Always check local
and state laws before installing snow
chains.
R Do not use snow chains on the spare wheel.
i When driving with snow chains, you may
wish to switch off the ESC ( Y page 66)
before setting the vehicle in motion. This
will improve the vehicle’s traction.Winter driving instructionsGWarning!
If the vehicle becomes stuck in snow, make
sure snow is kept clear of the exhaust pipe
and from around the vehicle with the engine
running. Otherwise, deadly carbon monoxide
(CO) gases may enter vehicle interior
resulting in unconsciousness and death.
To assure sufficient fresh air ventilation, open
a window slightly on the side of the vehicle
not facing the wind.
GWarning!
The outside temperature indicator is not
designed to serve as an ice-warning device
and is therefore unsuitable for that purpose.
Indicated temperatures just above the
freezing point do not guarantee that the road
surface is free of ice. The road may still be icy,
especially in wooded areas or on bridges.
GWarning!
On slippery road surfaces, never downshift in
order to obtain braking action. This could
result in drive wheel slip and reduced vehicle
control. Your vehicle’s ABS will not prevent
this type of loss of control.
The most important rule for slippery or icy
roads is to drive sensibly and to avoid abrupt
acceleration, braking and steering
maneuvers. Do not use the cruise control or
DISTRONIC PLUS system under such
conditions.
When the vehicle is in danger of skidding, shift
the automatic transmission to neutral
position N. Try to keep the vehicle under
control by corrective steering action.
i For information on driving with snow
chains, see “Snow chains” ( Y page 252).
Road salts and chemicals can adversely
affect braking efficiency. Increased pedal
force may become necessary to produce the
normal brake effect.
Winter driving253Operation212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 253Z

! Vehicles with 4MATIC:
Only conduct operational or performance
tests on a two-axle dynamometer. If such
tests are necessary, contact an authorized
Mercedes-Benz Center. You could
otherwise seriously damage the brake
system or the transfer case which is not
covered by the Mercedes-Benz Limited
Warranty.
! Vehicles with 4MATIC:
Because the ESC operates automatically,
the engine and ignition must be shut off
(SmartKey in starter switch position 0 or
1 or KEYLESS-GO start/stop button in
position 0 or 1) when the electronic parking
brake is being tested on a brake test
dynamometer.
Active braking action through the ESC may
otherwise seriously damage the brake
system which is not covered by the
Mercedes-Benz Limited Warranty.
! Vehicles without 4MATIC:
Because the ESC operates automatically,
the engine and ignition must be shut off
(SmartKey in starter switch position 0 or
1 or KEYLESS-GO start/stop button in
position 0 or 1) when the electronic parking
brake is being tested on a brake test
dynamometer or when the vehicle is being
towed with one axle raised.
Active braking action through the ESC may
otherwise seriously damage the brake
system which is not covered by the
Mercedes-Benz Limited Warranty.
If your brake system is only subjected to
moderate loads, you should occasionally test
the effectiveness of the brakes by applying
above-normal braking pressure at higher
speeds. This will also enhance the grip of the
brake pads.GWarning!
Make sure not to endanger any other road
users when carrying out these braking
maneuvers.
Refer to the description of the Brake Assist
System (BAS) ( Y page 63) or BAS PLUS
( Y page 63).
High-performance brake system and
ceramic brake system
The high-performance brake system and
ceramic brake system is only available on
E 63 AMG.
GWarning!
New vehicle brake pads and disks, and
replacement brake pads and disks may take
several hundred miles of driving until they
provide optimum braking efficiency. Until that
time, you may need to use increased brake
pedal pressure while braking. Please be aware
of this and adjust your driving and braking
accordingly during this break-in period.
Excessive high-demand braking will cause
correspondingly high brake wear. Please be
attentive to the brake warning lamp in the
instrument cluster and brake condition
messages in the multifunction display.
Especially for high performance driving, it is
important to maintain and have the brake
system checked regularly.
The high-performance brake system is
designed to operate under the extremely high
operating demands required to
accommodate the performance capabilities
of the vehicle.
The brakes may produce a squeaking-type
noise depending on the
R vehicle speed
R brake force applied
R ambient conditions, e.g. temperature and
humidity
As with any brake system, the wear of
individual brake system components such as
brake pads or disks strongly depends on your
driving style and the conditions under which
you operate the vehicle. Thus, a driving style
calling for high-demand braking will cause
your vehicle’s brakes to wear more quickly.
256Driving instructionsOperation
212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 256