2021 LEXUS RX350 ESP

6
Please note that this manual applies to
all models and explains all equipment,
including options. Therefore, you may
find some explanations for equipment
not installed on your vehicle.
All specifications provided in this man-
ual are current at the time of printing.
However, because of the Lexus policy
of continual product improvement, we
reserve the right to make changes at
any time without notice.
Depending on specifications, the vehi-
cle shown in the illustrations may differ
from your vehicle in terms of color and
equipment.
Approximately five hours after the
engine is turned off, you may hear
sound coming from under the vehicle
for several minutes. This is the sound of
a fuel evaporation leakage check and,
it does not indicate a malfunction.
A wide variety of non-genuine spare
parts and accessories for Lexus vehi-
cles are currently available in the mar-
ket. You should know that Toyota does
not warrant these products and is not
responsible for their performance, repair, or replacement, or for any dam-
age they may cause to, or adverse
effect they may have on, your Lexus
vehicle.
This vehicle should not be modified
with non-genuine Lexus products.
Modification with non-genuine Lexus
products could affect its performance,
safety or durability, and may even vio-
late governmental regulations. In addi-
tion, damage or performance
problems resulting from the modifica-
tion may not be covered under war-
ranty.
The installation of a mobile two-way
radio system in your vehicle could
affect electronic systems such as:

Multiport fuel injection sys-
tem/sequential multiport fuel injec-
tion system
 Lexus Safety System + 2.0
 Anti-lock brake system
 Vehicle dynamics integrated man-
agement
 SRS airbag system
 Seat belt pretensioner system
Be sure to check with your Lexus
dealer for precautionary measures or
special instructions regarding installa-
tion of a mobile two-way radio system.
The vehicle is equipped with sophisti-
For your information
Main Owner’s Manual
Noise from under vehicle after
turning off the engine
Accessories, spare parts and
modification of your Lexus
Installation of a mobile two-way
radio system
Vehicle data recording

7
cated computers that will record cer-
tain data, such as:
• Engine speed/Electric motor speed (traction motor speed)
• Accelerator status
•Brake status
• Vehicle speed
• Operation status of the driving assist systems
• Images from the cameras Your vehicle is equipped with cam-
eras. Contact your Lexus dealer for
the location of recording cameras.
The recorded data varies according to
the vehicle grade level and options
with which it is equipped.
These computers do not record con-
versations or sounds, and only record
images outside of the vehicle in certain
situations.
 Data Transmission
Your vehicle may transmit the data
recorded in these computers to Lexus
without notification to you.
Data usage
Lexus may use the data recorded in this
computer to diagnose malfunctions, con-
duct research and development, and
improve quality.
Lexus will not disclose the recorded data to
a third party except:
• With the consent of the vehicle owner or with the consent of the lessee if the vehi-
cle is leased
• In response to an of ficial request by the
police, a court of law or a government
agency
• For use by Lexus in a lawsuit
• For research purposes where the data is not tied to a specific vehicle or vehicle
owner

Recorded image information can be
erased by your Lexus dealer.
The image recording function can be dis-
abled. However, if the function is disabled,
data from when the system operates will
not be available.
To learn more abou t the vehicle data
collected, used and shared by
Lexus, please visit
www.lexus.com/privacyvts/
.
If your Lexus has Lexus Enform and if
you have subscribed to those services,
please refer to the Lexus Enform
Telematics Subscription Service
Agreement for information on data
collected and its usage.
To learn more about the vehicle data
collected, used and shared by Lexus,
please visit
www.lexus.com/privacyvts/
.
This vehicle is equipped with an event
data recorder (EDR). The main pur-
pose of an EDR is to record, in certain
crash or near crash-like situations, such
as an air bag deployment or hitting a
road obstacle, data that will assist in
understanding how a vehicle’s systems
performed. The EDR is designed to
record data related to vehicle dynam-
ics and safety systems for a short
Usage of data collected through
Lexus Enform (U.S. mainland on-
ly)
Event data recorder

8
period of time, typically 30 seconds or
less.
The EDR in this vehicle is designed to
record such data as:
• How various systems in your vehicle were operating;
• Whether or not the driver and pas- senger safety belts were buck-
led/fastened;
• How far (if at all) the driver was depressing the accelerator and/or
brake pedal; and,
• How fast the vehicle was traveling.
These data can help provide a better
understanding of the circumstances in
which crashes and injuries occur.
NOTE: EDR data are recorded by your
vehicle only if a non-trivial crash situa-
tion occurs; no data are recorded by
the EDR under normal driving condi-
tions and no personal data (e.g., name,
gender, age, and crash location) are
recorded. However, other parties, such
as law enforcement, could combine the
EDR data with the type of personally
identifying data routinely acquired
during a crash investigation.
To read data recorded by an EDR, spe-
cial equipment is required, and access
to the vehicle or the EDR is needed. In
addition to the vehicle manufacturer,
other parties, such as law enforcement,
that have the special equipment, can
read the information if they have
access to the vehicle or the EDR.
 Disclosure of the EDR data
Lexus will not disclose the data recorded in
an EDR to a third party except when: • An agreement from the vehicle’s owner
(or the lessee for a leased vehicle) is
obtained
• In response to an official request by the police, a court of law or a government
agency
• For use by Lexus in a lawsuit
However, if necessary, Lexus may:
• Use the data for research on vehicle safety performance
• Disclose the data to a third party for research purposes without disclosing
information about the specific vehicle or
vehicle owner
The SRS airbag and seat belt preten-
sioner devices in your Lexus contain
explosive chemicals. If the vehicle is
scrapped with the airbags and seat belt
pretensioners left as they are, this may
cause an accident such as fire. Be sure
to have the systems of the SRS airbag
and seat belt pretensioner removed
and disposed of by a qualified service
shop or by your Lexus dealer before
you scrap your vehicle.
Special handling may apply, See
www.dtsc.ca.gov/hazard-
ouswaste/perchlorate.
Your vehicle has components that may
contain perchlorate. These compo-
nents may include the airbags, seat belt
pretensioners, wireless remote control
batteries, and the batteries in the tire
pressure warning valve and transmit-
Scrapping of your Lexus
Perchlorate Material

241-1. For safe use
1-1.For safe use
Use only floor mats designed specifi-
cally for vehicles of the same model
and model year as your vehicle. Fix
them securely in place onto the carpet.
1Insert the retaining hooks (clips)
into the floor mat eyelets.
2 Turn the upper knob of each retain-
ing hook (clip) to secure the floor
mats in place.
Always align the marks .
The shape of the reta ining hooks (clips)
may differ from that shown in the illustra-
tion.
Before driving
Observe the following before start-
ing off in the vehicle to ensure
safety of driving.
Installing floor mats
A
WARNING
Observe the following precautions.
Failure to do so may cause the driver’s
floor mat to slip, poss ibly interfering with
the pedals while driv ing. An unexpect-
edly high speed may result or it may
become difficult to stop the vehicle. This
could lead to an accident, resulting in
death or serious injury.
■When installing the driver’s floor mat
●Do not use floor mats designed for
other models or different model year
vehicles, even if they are Lexus Genu-
ine floor mats.
●Only use floor mats designed for the
driver’s seat.
●Always install the floor mat securely
using the retaining hooks (clips) pro-
vided.
●Do not use two or more floor mats on
top of each other.
●Do not place the floor mat bot-
tom-side up or upside-down.
■Before driving
●Check that the floor mat is securely
fixed in the correct place with all the
provided retaining hooks (clips). Be
especially careful to perform this
check after cleaning the floor.
●With the engine stopped and the shift
lever in P, fully depress each pedal to
the floor to make sure it does not inter-
fere with the floor mat.

331-1. For safe use
1
For safety and security
RX350L: Rear side airbags (outboard second-row seats)
Your vehicle is equipped with ADVANCED AIRBAGS designed based on the US
motor vehicle safety standards (FMVSS208). The airbag sensor assembly (ECU)
controls airbag deployment based on information obtained from the sensors etc.
shown in the system components diagram above. This information includes crash
severity and occupant information. As the airbags deploy, a chemical reaction in
the inflators quickly fills the airbags with no n-toxic gas to help restrain the motion of
the occupants.
■If the SRS airbags deploy (inflate)
●Slight abrasions, burns, bruising etc., may
be sustained from SRS airbags, due to the
extremely high speed deployment (infla-
tion) by hot gases.
●A loud noise and white powder will be
emitted.
●Parts of the airbag module (steering
wheel hub, airbag cover and inflator) as
well as the front seat s, parts of the front
and rear pillars, and roof side rails, may
be hot for several minutes. The airbag
itself may also be hot.
●The windshield may crack.
●All of the doors will be unlocked.
(  P.100)
●The brakes and stop lights will be con-
trolled automatically. ( P.275)
●The interior lights will turn on automati-
cally. ( P.310)
●The emergency flashers will turn on auto-
matically. ( P.394)
●Fuel supply to the engine will be stopped.
( P.402)
●For Lexus Enform Safety Connect sub-
scribers, if any of the following situations
occur, the system is designed to send an
emergency call to the response center,
notifying them of the vehicle’s location
(without needing to push the “SOS” but-
ton) and an agent will attempt to speak
with the occupants to ascertain the level
of emergency and assi stance required. If
the occupants are unable to communi-
cate, the agent automatically treats the
call as an emergency and helps to dis-
patch the necessary emergency services. (
 P.60)
• An SRS airbag is deployed.
• A seat belt pretensioner is activated.
• The vehicle is involved in a severe rear-end collision.
■SRS airbag deployment conditions (SRS
front airbags)
●The SRS front airbags will deploy in the
event of an impact that exceeds the set
threshold level (the level of force corre-
sponding to an approximately 12 - 18
mph [20 - 30 km/h] frontal collision with
a fixed wall that does not move or
deform).
However, this threshol d velocity will be
considerably higher in the following situa-
tions:
• If the vehicle strikes an object, such as a parked vehicle or sign pole, which can
move or deform on impact
• If the vehicle is involved in an underride collision, such as a collision in which the
front of the vehicle “underrides”, or goes
under, the bed of a truck
●Depending on the type of collision, it is
possible that only the seat belt preten-
sioners will activate.
●The SRS seat cushion airbag on the front
passenger seat will not operate if the
occupant is not wearing a seat belt.
■SRS airbag deployment conditions (SRS
side and curtain shield airbags)
●The SRS side and curtain shield airbags
will deploy in the event of an impact that
exceeds the set threshold level (the level
of force corresponding to the impact
force produced by an approximately
3300 lb. [1500 kg] vehicle colliding with
the vehicle cabin from a direction per-

361-1. For safe use
WARNING
■SRS airbag precautions
Observe the following precautions
regarding the SRS airbags.
Failure to do so may cause death or seri-
ous injury.
●The driver and all passengers in the
vehicle must wear their seat belts
properly.
The SRS airbags are supplemental
devices to be used with the seat belts.
●The SRS driver airbag deploys with
considerable force, and can cause
death or serious injury especially if the
driver is very close to the airbag.
The National Highway Traffic Safety
Administration (NHTSA) advises:
Since the risk zone for the driver’s air-
bag is the first 2 - 3 in. (50 - 75 mm) of
inflation, placing yourself 10 in. (250
mm) from your driver airbag provides
you with a clear margin of safety. This
distance is measured from the center
of the steering wheel to your breast-
bone. If you sit less than 10 in. (250
mm) away now, you can change your
driving position in several ways:
• Move your seat to the rear as far as you can while still reaching the pedals
comfortably.
• Slightly recline the back of the seat. Although vehicle designs vary, many
drivers can achieve the 10 in. (250
mm) distance, even with the driver seat
all the way forward, simply by reclining
the back of the seat somewhat. If
reclining the back of your seat makes it
hard to see the road, raise yourself by
using a firm, non-slippery cushion, or
raise the seat if your vehicle has that
feature.
• If your steering wheel is adjustable, tilt it downward. This points the airbag
toward your chest instead of your head
and neck.
The seat should be adjusted as recom-
mended by NHTSA above, while still
maintaining control of the foot pedals,
steering wheel, and your view of the
instrument panel controls.
●If the seat belt extender has been con-
nected to the front seat belt buckles
but the seat belt extender has not also
been fastened to the latch plate of the
seat belt, the SRS front airbags will
judge that the driver and front passen-
ger are wearing the seat belt even
though the seat belt has not been con-
nected. In this case, the SRS front air-
bags may not activate correctly in a
collision, resulting in death or serious
injury in the event of a collision. Be
sure to wear the seat belt with the seat
belt extender.

371-1. For safe use
1
For safety and security
WARNING
●The SRS front passenger airbag also
deploys with considerable force, and
can cause death or serious injury
especially if the front passenger is very
close to the airbag. The front passen-
ger seat should be as far from the air-
bag as possible with the seatback
adjusted, so the front passenger sits
upright.
●Improperly seated and/or restrained
infants and children can be killed or
seriously injured by a deploying airbag.
An infant or child who is too small to
use a seat belt should be properly
secured using a child restraint system.
Lexus strongly recommends that all
infants and children be placed in the
rear seats of the vehicle and properly
restrained. The rear seats are safer for
infants and children than the front pas-
senger seat. (
P.45)
●Do not sit on the edge of the seat or
lean against the dashboard.
●Do not allow a child to stand in front of
the SRS front passenger airbag unit or
sit on the knees of a front passenger.
●Do not allow the front seat occupants
to hold items on their knees.
●Do not lean against the door, the roof
side rail or the front, side and rear pil-
lars.
●Do not allow anyone to kneel on the
passenger seats toward the door or
put their head or hands outside the
vehicle.
●Do not attach anything to or lean any-
thing against areas such as the dash-
board, steering wheel pad and lower
portion of the instrument panel.
These items can become projectiles
when the SRS driver, front passenger
and knee airbags deploy.

601-3. Lexus Enform
1-3.Lexus Enform
*:If equipped
“SOS” button
LED light indicators
Microphone
Lexus Enform Safety Con-
nect*
Safety Connect is a subscrip-
tion-based telematics service that
uses Global Positioning System
(GPS) data and embedded cellular
technology to provide safety and
security features to subscribers.
Safety Connect is supported by
Lexus’ designated response center,
which operates 24 hours per day, 7
days per week.
Safety Connect service is available
by subscription on select, telemat-
ics hardware-equipped vehicles.
By using the Safety Connect ser-
vice, you are agreeing to be bound
by the Telematics Subscription Ser-
vice Agreement and its Terms and
Conditions, as in effect and
amended from time to time, a cur-
rent copy of which is available at
Lexus.com. All use of the Safety
Connect service is subject to such
then-applicable Terms and Condi-
tions.
System components
A
B
C