
General notes............................................... 4
Operator's Manual .......................................... 4
Operating saf ety............................................ .4
Qualified specialist workshop .........................5
Cor rect use of theve hicle ...............................5
Limited Warranty ............................................ 6
At agl ance .................................................... 8
Cockpit ........................................................... 8
Seat belts .................................................... 11
Re duced pr otection ....................................... 11
Seats........................................................... 12
Ad justing the AMG per form ance seat .......... .12
Drivin g........................................................ .13
No tes on breaking-in a new vehicle .............. 13
No tes on there ar axle locking dif fere ntial .... 13
Operation of the ECO start/ stop function ....1 3
AMG Performance exhaust sy stem ............... 14Ti
ps forth e AMG ceramic high-per form ‐
ance composite brake sy stem ..................... .15
DYNA MIC SELECT switch ...........................16
Fu nction of theDY NA MIC SELECT switch ..... 16
Fu nction of theDY NA MIC SELECT switch ..... 16
Confi guring drive program I .......................... 17
Automatic transmission ............................18
Manual gearshifting ...................................... 18
Gearshift recommendation ........................... 19
Using kickdown ............................................ 19
Glide mode function .................................... .19
Drivin gand drivin gsaf ety sy stems .......... 21
Fu nctions of ESP®(Electronic Stability
Program) ...................................................... .21
Ac tivating/deactivating ESP
®(Electronic
St ability Prog ram) .........................................2 3
RACE START ................................................. 23
AMG adaptive spo rtsuspension sy stem .......2 5
Instrument Display and on-board
computer.................................................... 30
No tes on the instrument display and on-
board computer ............................................ 30
Calling up displa ysinthePe rformance
menu ............................................................ 30
Displaying and starting the RACETIMER
in thePe rformance menu ............................. 32
Fu nction of the Head-up Display .................. .33
Wheels and tires ........................................ 34
Changing a wheel ........................................ .34
Tech nical data ............................................ 35
Operating fluids .. .......................................... 35
Ve hicle data .................................................. 36
Display messages and warning/indi‐
cator lamps ................................................ 39
Display messages ........................................ .39
Wa rning and indicator lamps ........................ .41
2
Conte nts

1Steering wheel gearshift paddle →
18
2 Combination switch
3 DIRECT SELECT le ver
4 Displ ay(multimedia sy stem)
5 Start/ Stop button
6 Control panel forth e multimedia sy stem
7 Climate control sy stems
8 Glovebox
9 Hazard warning lights
A Stow age compartment
B Controls forth e multimedia sy stem
C AMG Performance exhaust sy stem (Mercedes-
AMG E 63 4MATIC and E63 S 4MATIC only) →
14
D ECO start/ stop function
E Parking Pilot
F Toactivate/deactivate ESP
®→
21
To activate/deactivate SPO RThandling mode →
21
GAMG RIDE CONTROL (suspension tuning) →
25
H Manual gearshifting (permanent setting) →
18
I DYNA MIC SELECT switch
J PASSENGER AIRB AGindicator lamps
K Cont rol panel forth e multimedia sy stem
L Toadjust thesteering wheel
M Control panel forth e on-board computer
N Cruise control le ver
O Tounlo ckthe hood
P Elect ric park ing brake
Q Light switch
R Cont rol panel for:
St eering Pilot
Ac tive Lane Keeping Assist
Pa rking Assist PARKTRONI C
Head-up Displa y
Ataglance – Cockpit 9

Notes on breaking-in a new vehicle
To preser vethe engine during thefirs t
1, 000 miles (1,500 km):
RDrive at varying road speeds and engine
speeds.
RDo not drive fasterthan 85 mph (140 km/h).
ROnly brief lyallow the engine toreach a maxi‐
mum engine speed of 4,500 rpm
(4,500 1/min) only brief ly.
RMercedes-AMG E 43 4MATIC: Drive in drive
program Cor E.
RMercedes‑AMG E 63 4MATIC and
Mercedes‑AMG E 63 S 4MATIC: Drive in
drive program C.
RChange up before theta ch ome ter needle is
Ô ofthewa yto there d area of theta ch ome‐
te r.
RDo not shi ftdown a gear manually in order to
brake.
RAv oid overstra ining theve hicle, e.g. driving at
full thro ttle.
RDo not depress the accelera tor pedal be yond
th e pressure point (kickdown).
ROnly increase the engine speed gradually and
accelera tetheve hicle tofull speed af ter
1, 000 miles (1,500 km).
This also applies when the engine or parts of the
driv etra in ha vebeen replaced.
Please also obser vethefo llowing running-in
no tes:
RIn cer tain driving and driving saf etysy stems,
th e sensors adjust automatically while a cer‐
ta in dis tance is being driven af terth eve hicle
has been delivered or af terre pairs.
Full sys‐
te m ef fecti
veness is not achie ved until the
end of this teach-in process.
RBrake linings, brake discs and tires that are
either new or ha vebeen replaced only ach‐
ie ve optimum braking ef fect and grip af ter
se veral hundred kilom eters of driving. Com‐
pensate forth ere duced braking ef fect by
applying greaterfo rc eto the brake pedal.
Note s onthere ar axle locking dif fere ntial
The rear axle locking dif fere ntial is only
av ailable for the
Merc edes‑AMG E 63 4MATIC and
Mercedes‑AMG E 63 S 4MATIC models.
Changing the oil at there ar axle prolongs the
service life of the dif fere ntial.
Ha ve the oil change car ried out at a qualified
specialist workshop:
RAf ter a breaking-in period of 2000 miles
(3000 km).
REvery 30000 miles (50000 km) or thre e
ye ars.
Operation of the ECO start/s top function
The engine is switched off au tomatical ly:
RIf yo u brake theve hicle toast andstill in
transmission position hori.
RIf all vehicle conditions for an au tomatic
engine stop are met.
The è symbol appears in the multifunction
display when theve hicle is stationar y.
Driving 13

The engine isrestar ted automatically if:
RYo ure lease the brake pedal with the trans‐
mission in position hwhen the HOLD func‐
tion is not active.
RYo u shift from transmission position j.
RYou enga getransmission position hork.
RYoudepr essthe accelerator pedal.
RMercedes-AMG E 43 4MATIC: Youswit chto
drive program S+.
RMercedes-AMG E 63 4MATIC: Youswit chto
drive prog ram Sor S+.
RMercedes-AMG E 63 S 4MATIC: Youswit ch
to drive prog ram S, S+ orRACE .
RYou permanently act ivate manual gearshift‐
ing.
RYo upull the left-hand steering wheel gear‐
shift paddle.
RYo uch ange theve hicle le vel.
RAn automatic engine start is necessar y.
If th e engine was switched off bythe ECO start/
st op function and you lea vetheve hicle, a warn‐ ing
tone sounds. The Vehicle Operational Switch
the Ignition Off Before Exiting displaymessage
also appears in the multifunction displa y.
If yo udo not swit choff the ignition, the ignition
is automatically switched off af ter one minute.
AMG Performance exhaust sy stem
Fu nction of the AMG Performance exhaust
sy stem
The AMG Performance exhaust sy stem is
only available for the
Merc edes‑AMG E 63 4MATIC and
Mercedes‑AMG E 63 S 4MATIC models.
Changing the position of theex haust gasflap
allo wsyouto select thevo lume of the AMG Per‐
fo rm ance exhaust sy stem.
Operating the AMG Performance exhaust
sy stem
#Press button 1.
If indicator lamp 2lights up, the loudest
setting is selected.
14 Driving

Tips for the AMG ce ramic high-perf ormance
composite brake sy stem
The AMG ceramic high-per form ance co mpo‐
site brake sy stem is only available for the
Merc edes‑AMG E 63 S 4MATIC model.
The AMG ceramic high-per form ance composite
brake sy stem is designed for heavy loads. This
may lead tonoise when braking.
The noise depends on thefo llowing factors:
RSpeed
RBrake forc e
REnvironmental conditions such astemp era‐
ture and air humidity
Ha ve the brake sy stem checked at a qualified
specialist workshop af ter it has been subjected
to extreme use.
Driving 15

RThe engine speed corresponds tothe idle
speed.
RSt atus icon 1is shown in the multifunction
displa y.
Glide mode is activated if thefo llowing condi‐
tions are me t:
RThe ECOstart/ stop function is activated.
RMercedes-AMG E 43 4MATIC: Drive pro‐
gram Eis selected.
RMercedes‑AMG E 63 4MATIC and
Mercedes‑AMG E 63 S 4MATIC: Drive pro‐
gram Cis selected.
RYo u are no longe r depressingthe accelera tor
or brake pedal.
RThe speed is within a suitable range.
RThe cours e ofthero ad is suitable, e.g. no
st eep uphill or downhill gradients.
% Mercedes-AMG E 43 4MATIC: Glide mode
can also be activated if you ha veselected
th e "Eco" setting forth e drive (engine man‐
agement) in drive program I.%
Mercedes‑AMG E 63 4MATIC and
Mercedes‑AMG E 63 S 4MATIC:
Glide
mode can also be activated if you ha ve
selected the "Comfort" setting forth e drive
(engine management) in drive program I.
Glide mode is deactivated again if one of the
conditions is no longer met.
20 Automatic transmission

Functions of ESP®(Electronic Stability Pro‐
gr am)
&
WARNING Risk of skidding if ESP®is
malfunctioning
If ESP
®is malfunctioning, ESP®cannot car ry
out vehicle stabilization. In addition, other
driving saf etysy stems are switched off.
#Drive on carefull y.
#Have ESP®checked at a qualified spe‐
cialist workshop.
Yo u can select between thefo llowing modes of
ESP®:
RESP®on
RSPO RThandling mode on
RESP®off
Characteristics when ESP
®is activated
ESP
®monitors and impr oves driving stability and
traction, particular lyin thefo llowing situations:
RWhen pulling away on wet or slippe ryroads.
RWhen braking.
RIn stro ng sidewinds when you are driving
fast erthan 43 mph (70 km/h).
ESP
®can stabilize theve hicle byinter vening in
th efo llowing ways:
ROne or more wheels are braked.
RThe engine output is adap ted according to
th e situation.
ESP
®is activated everytime the engine is star‐
te d, rega rdless of whe ther ESP®wa s in SPORT
handling mode or was deactivated before the
engine was switched off.
ESP
®is inter vening if the ESP®÷ warning
lamp flashes in the instrument clus ter:
RDo not deacti vate ESP®.
ROnly depress the accelera tor pedal as far as
is necessar y.
RAdapt your drivin gst yle to suit the cur rent
ro ad and weather conditions. Cha
racteristics of activated SPORT handling
mode
& WARNING Risk of skidding due toincor‐
re ct application of SPORT handling mode
When you activate SPORT handling mode,
th ere is an increased risk of skidding and
having an accident.
#Only activate SPORT handling mode in
th e circums tances described as follo ws .
Select SPORT handling mode when theve hicle's
ow nov ersteering and under steering characteris‐
tics are desired, forex ample when driving on
specially designated roads.
Only a highly qu alified and experienced driver
should drive in SPORT handling mode or with
ESP
®switched off.
If SPORT handling mode is activated and one or
more wheels start tospin, the÷ ESP
®warn‐
ing lamp in the instrument clus terflashes. ESP®
th en only stabilizes theve hicle toa limited
deg ree.
Driving and driving saf etysy stems 21

If SPORT handling mode is activated:
RESP®only improves driving stability toa limi‐
te d deg ree.
RETS/4ETS traction control is still active.
RThe engine's torque is on lyrestricted toa
limited degree and the drive wheels can spin.
The spinning of the wheels results in a cut‐
ting action for better traction on loose sur fa‐
ces.
RESP®continues toprov ide assis tance when
th e brakes are firm lyapplied.
Cha racteristics when ESP
®is deactivated
&
WARNING Risk of skidding if ESP®is
deactivated
If yo u deactivate ESP
®, ESP®cannot car ry
out vehicle stabilization.
#ESP®should only be deactivated in the
fo llowing situations.
ESP®is deactivated if the ESP®OFF å warn‐
ing lamp lights up continuously in the instrument
clus ter:
RDriving stability will no longe r be improved.
RCrosswind Assist is no longer active.
RThe drive wheels could spin.
RETS/4ETS traction control is still active.
% Even when ESP
®is deactivated, you are still
assis tedby ESP®when braking hard .
In thefo llowing situations, it may be better to
activate SPO RThandling mode or deactivate
ESP
®:
RWhen using snow chains
RIn deep snow
Ron sand or gr avel
% Spinning the wheels results in a cutting
action which pr ovides better grip.
% Activate ESP
®as soon as the situations
described abo veno longer apply. ESP®will
ot herwise not be able tostabilize theve hicle if
th eve hicle starts toskid or a wheel starts
to spin.
If th e ESP
®÷ warning lamp lights up continu‐
ousl y,ESP®is not available due toa malfunction.
Observ e any information which may be displa yed
in the instrument clus ter:
RWa rning and indicator lamps
RDisplay messages
ETS/4ETS (Electronic Traction Sy stem)
ETS/4ETS traction control is pa rtof ESP
®.
ETS/4ETS can impr oveth eve hicle's traction by
inter vening in thefo llowing ways:
RThe drive wheels are braked individually if
they spin.
RMore drive torque is transferred tothe wheel
or wheels with traction.
22 Driving and driving saf etysy stems