
3
1
9 8
7 5 4
3
2
10
IS350/250_U (OM53C50U)
6
4-1. Before driving Driving the vehicle ......................146
Cargo and luggage.....................153
Vehicle load limits ........................156
Trailer towing ................................. 157
Dinghy towing .............................. 158
4-2. Driving procedures Engine (ignition) switch .............159
Automatic transmission ............164
Turn signal lever ............................ 170
Parking brake ................................ 172
4-3. Operating the lights and wipers
Headlight switch .......................... 173
Automatic High Beam............... 176
Fog light switch .............................. 181
Windshield wipers and washer .......................................... 182
4-4. Refueling Opening the fuel tank cap ...... 188 4-5. Using the driving
support systems
Cruise control ...............................192
Dynamic radar cruise control ...........................................196
LDA (Lane Departure Alert)........208
Intuitive parking assist ................214
Lexus parking assist monitor.......................................... 221
Driving mode select switch ............................................237
Driving assist systems .............. 240
PCS (Pre-Collision System) ..........246
BSM (Blind Spot Monitor) ............. 252
•The Blind Spot Monitor function .................................... 255
• The Rear Cross Traffic Alert function .........................257
4-6. Driving tips Winter driving tips ..................... 260
4Driving

15Pictorial index
IS350/250_U (OM53C50U)
Windshield wipers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Precautions against winter season . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 260
To prevent freezing (windshield wiper de-icer)
* . . . . . . . . . . . . . . . . . . . . . . . . P. 362
Precautions against car wash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 397
Fuel filler door . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 1 8 8
Refueling method . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 188
Fuel type/fuel tank capacity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 514
Tires . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 423
Tire size/inflation pressure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 519
Winter tires/tire chain. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 260
Checking/rotation/tire pressure warning system . . . . . . . . . . . . . . . . . . . . . . . .P. 423
Coping with flat tires . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 486
Hood . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 411
Opening. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 411
Engine oil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 514
Coping with overheat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 506
Warning messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 4 74
Headlights/parking lights/daytime running lights . . . . . . . . . . . . . . . . . . . P. 173
Fog lights
* . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 181
Turn signal lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 170
Tail lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 173
Stop lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 146
License plate lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 17 3
Back-up lights
Shifting the shift lever to R . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 16 4
Side marker lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 173
4
5
6
7
Light bulbs of the exterior lights for driving(Replacing method: P. 444, Watts: P. 521)
*: If equipped
8
9
10
11
12
13
14
15

17Pictorial index
IS350/250_U (OM53C50U)
Multi-information display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 86
Display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 86
When the warning messages are displayed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 472
Parking brake . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 172
Applying/releasing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 1 7 2
Precautions against winter season . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 261
Warning buzzer/message. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 472
Turn signal lever. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 170
Headlight switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 173
Headlights/parking lights/tail lights/daytime running lights . . . . . . . . . . . . . . P. 173
Fog lights
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 181
Windshield wiper and washer switch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Adding washer fluid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 4 22
Warning messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 47 9
Emergency flasher switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 456
Trunk opener. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 109
Hood lock release lever . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 411
Tilt and telescopic steering control switch
*1. . . . . . . . . . . . . . . . . . . . . . . . . P. 131
Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 131
Driving position memory
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 123
Tilt and telescopic steering lock release lever*1. . . . . . . . . . . . . . . . . . . . . P. 131
Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 131
Air conditioning system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 358
Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 358
Rear window defogger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 362
Audio system*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 266
Audio system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 266
Hands-free system. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 319
Trunk opener main switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 110
*1: If equipped
*2: For vehicles with a navigation system, refer to “NAVIGATION SYSTEM OWNER’S
MANUAL”.
4
5
6
7
8
9
10
11
12
13
14
15

145
Driving4
IS350/250_U (OM53C50U)
4-1. Before drivingDriving the vehicle ...................... 146
Cargo and luggage .................... 153
Vehicle load limits ....................... 156
Trailer towing ................................. 157
Dinghy towing...............................158
4-2. Driving procedures Engine (ignition) switch ............ 159
Automatic transmission ............ 164
Turn signal lever ........................... 170
Parking brake .................................172
4-3. Operating the lights and wipers
Headlight switch ...........................173
Automatic High Beam ............... 176
Fog light switch.............................. 181
Windshield wipers and washer........................................... 182
4-4. Refueling Opening the fuel tank cap.......188 4-5. Using the driving support
systems
Cruise control .............................. 192
Dynamic radar cruise control .......................................... 196
LDA (Lane Departure Alert) ........208
Intuitive parking assist ................214
Lexus parking assist monitor ..........................................221
Driving mode select switch ........................................... 237
Driving assist systems............... 240
PCS (Pre-Collision System).......... 246
BSM (Blind Spot Monitor) ..... 252
• The Blind Spot Monitor function .................................... 255
• The Rear Cross Traffic Alert function......................... 257
4-6. Driving tips Winter driving tips ..................... 260

1704-2. Driving procedures
IS350/250_U (OM53C50U)
The lever will return to its original position after operation. Right turn
Lane change to the right (move the
lever partway and release it)
The right hand signals will flash 3 times.
Lane change to the left (move the
lever partway and release it)
The left hand signals will flash 3 times.
Left turn
■If the turn signals do not stop flashing af ter turning left or right, or if you want
to stop them flashing
Operate the lever in the opposite direction to either position or . If you
move the lever to either position or , the selected turn signals will flash.
Turn signal lever
Operating instructions
1
2
3
4
23
14

1864-3. Operating the lights and wipers
IS350/250_U (OM53C50U)
■The windshield wiper and washer can be operated when
The engine switch is in IGNITION ON mode.
■Dripping prevention wiper sweep
After performing a washing and wiping operation several times, the wipers operate one
more time after a short delay to prevent dripping.
However, the last sweep will not happen if the vehicle is traveling above 106 mph (170
km/h).
■Effects of vehicle speed on wiper operation (vehicles with rain-sensing windshield wip-
ers)
Vehicle speed affects the following even when the wipers are not in AUTO mode.
●Intermittent wiper interval
●Wiper operation when the washer is being used (delay until drip prevention wiper
sweep occurs)
With low speed windshield wiper operation selected, wiper operation will be switched
from low speed to intermittent wiper operat ion only when the vehicle is stationary.
■Raindrop sensor (vehicles with rain-sensing windshield wipers)
●If the wiper is turned to AUTO mode while the engine switch is in IGNITION ON
mode, the wipers will operate once to show that AUTO mode is activated.
●If the temperature of the raindrop sensor is 185°F (85°C) or higher, or -22°F (-30°C)
or lower, automatic operation may not occur. In this case, operate the wipers in any
mode other than AUTO mode.
■When the windshield wipers are in temporary operation (vehicles with rain-sensing
windshield wipers)
AUTO mode cannot be activated even if is pressed.
■If no windshield washer fluid sprays
Check that the washer nozzles are not blocked if there is washer fluid in the windshield
washer fluid reservoir.
■Operation guide display (vehicles with rain-sensing windshield wipers only)
When the windshield wiper switch is operated to activate AUTO mode or when the rain-
sensing level is adjusted, the current status is displayed on the meters for a few seconds.
( → P. 8 9 )
●The raindrop sensor judges the amount of
raindrops.
An optical sensor is ad opted. It may not oper-
ate properly when sunlight from the rising or
setting of the sun intermittently strikes the
windshield, or if bugs etc. are present on the
windshield.

2925-4. Using the radio
IS350/250_U (OM53C50U)
■Reception sensitivity
●Maintaining perfect radio reception at all times is difficult due to the continually chang-
ing position of the antenna, differences in signal strength and surrounding objects, such
as trains, transmitters, etc.
●The radio antenna is mounted inside the rear window. To maintain clear radio reception,
do not attach metallic window tinting or other metallic objects to the antenna wire
mounted inside the rear window.
■XM Radio Services — Descriptions
●Radio and Entertainment
XM offers more than 170 satellite radio channels of commercial-free music and pre-
mier sports, news, talk, and entertainment. XM is broadcast via satellites to millions of
listeners across the continental United States . XM subscribers listen to XM on satellite
radio receivers for the car, home, and portable use. More information about XM is
available online at www.siriusxm.com
(U.S.A.) or www.xmradio.ca (Canada).
●Satellite tuner
The tuner supports only Audio Services (Music and Talk) and the accompanying Text
Information of XM Satellite Radio.
Audio mute condition
when an HD2 /HD3 multi-
cast channel had been
playing.The radio does not have
access to digital signals at
the moment.This is normal behavior,
wait until the digital signal
returns. If out of the cover-
age area, seek a new sta-
tion.
Audio mute delay when
selecting an HD2 /HD3
multicast channel preset.
The digital multicast con-
tent is not available until
HD Radio™ broadcast can
be decoded and make the
audio available. This takes
up to 7 seconds.
This is normal behavior,
wait for the audio to
become available.
Te x t i n f o r m a t i o n d o e s n o t
match the present song
audio.Data service issue at the
radio broadcaster.
Broadcaster should be
notified. Complete the
form: www.ibiquity.com/
automotive/report_radio_station_
experiences.
No text information shown
for the present selected
frequency.Data service issue by the
radio broadcaster.
Broadcaster should be
notified. Complete the
form: www.ibiquity.com/
automotive/report_radio_station_experiences.
ExperienceCauseAction

409
IS350/250_U (OM53C50U)
7
Maintenance and care
7-3. Do-it-yourself maintenance
Do-it-yourself service precautions
If you perform maintenance by yourself, be sure to follow the correct proce-
dure as given in these sections.
ItemsParts and tools
Battery condition
(→ P. 4 2 0 )•Warm water• Baking soda•Grease
• Conventional wrench (for terminal clamp bolts)
Brake fluid level
(→ P. 4 1 9 )• SAE J1703 or FMVSS No.116 DOT 3 brake fluid
• Rag or paper towel
• Funnel (used only for adding brake fluid)
Engine coolant level
(→ P. 4 1 7 )
• “Toyota Super Long Life Coolant” or a similar high quality
ethylene glycol-based non-silicate, non-amine, non-nitrite
and non-borate coolant with long-life hybrid organic acid
technology
For the U.S.A.:
“Toyota Super Long Life Coolant” is pre-mixed with 50%
coolant and 50% deionized water.
For Canada:
“Toyota Super Long Life Coolant” is pre-mixed with 55%
coolant and 45% deionized water.
• Funnel (used only for adding coolant)
Engine oil level
(→ P. 4 1 4 )• “Toyota Genuine Motor Oil” or equivalent
• Rag or paper towel
• Funnel (used only for adding engine oil)
Fuses
(→ P. 4 4 1 )• Fuse with same amperage rating as original
Light bulbs
(→ P. 444)
• Bulb with same number and wattage rating as original
• Phillips-head screwdriver•Flathead screwdriver
•Wrench
Radiator and con-
denser ( →P. 4 1 8 )
Tire inflation pres-
sure ( →P. 4 3 2 )• Tire pressure gauge• Compressed air source
Wa s h e r f l u i d
(→ P. 4 2 2 )• Water or washer fluid containing antifreeze (for winter use)
• Funnel (used only for adding water or washer fluid)