Page 466 of 784
4666-1. Using the air conditioning system and defogger
ES350_300h_OM_OM33B99U_(U)
Vehicles with a Lexus Display Audio System
Adjust the left-hand side temper-
ature setting
Adjust the fan speed setting
“AUTO”: Select to set automatic
mode on/off
“OFF”: Turn the fan off: Display the option control
screen ( P. 468)
Select the air flow mode : Air flows to the upper body
: Air flows to the upper body and feet
: Air flows to the feet
: Air flows to the feet and the windshield defogger operates
Adjust the right-hand side temperature setting
Move the Lexus Display Audio controll er left/right to select the desired
item ( to ).
When , or is selected:
Move the controller forward/backward or turn it left/right for adjusting.
When or is selected:
Move the controller forward/backward or turn it left/right to select a
screen button, then press the controller.
Control screen
1
2
3
4
5
1
15
2125
34
Page 468 of 784
4686-1. Using the air conditioning system and defogger
ES350_300h_OM_OM33B99U_(U)
■Option control screen
Select on the climate screen to display the option control screen.
The functions can be switched on and off.
Select to set cooling and de humidification function on/off
Adjusting the temperature for driv er and passenger seats separately
(“DUAL” mode) ( P. 469)
Prevent ice from building up on the windshield and wiper blades (if
equipped) ( P. 4 7 1 )
Remove pollen from the air (Micro dust and pollen filter) ( P. 471)
Vehicles with a Lexus Display
Audio systemVehicles with a navigation sys-
tem
1
2
3
4
Page 528 of 784

528
ES350_300h_OM_OM33B99U_(U)
7-1. Maintenance and care
NOTICE
■Cleaning detergents
●Do not use the following types of detergent, as they may discolor the vehicle inte-
rior or cause streaks or damage to painted surfaces:
• Non-seat portions: Organic substances such as benzene or gasoline, alkalineor acidic solutions, dye, and bleach
• Seats: Alkaline or acidic solutions, such as thinner, benzene, and alcohol
●Do not use polish wax or polish cleaner. The instrument panel’s or other interior
part’s painted surf ace may be damaged.
■Preventing damage to leather surfaces
Observe the following precautions to avoid damage to and deterioration of
leather surfaces:
●Remove any dust or dirt from leather surfaces immediately.
●Do not expose the vehicle to direct sunlight for extended periods of time. Park
the vehicle in the shade, especially during summer.
●Do not place items made of vinyl, plastic, or containing wax on the upholstery, as
they may stick to the leather surface if the vehicle interior heats up significantly.
■Water on the floor
Do not wash the vehicle floor with water.
Vehicle systems such as the audio syst em may be damaged if water comes into
contact with electrical components such as the audio system above or under the
floor of the vehicle. Water may also cause the body to rust.
■When cleaning the inside of the windshield (vehicles with LDA [Lane Departure
Alert] and Automatic High Beam)
Be careful not to touch the camera sensor ( P. 2 7 9 ) .
If the camera is accidentally scratched or hit, LDA and Automatic High Beam sys-
tem may not operate properly or may cause a malfunction.
■Cleaning the inside of the rear window
●Do not use glass cleaner to clean the rear window, as this may cause damage to
the rear window defogger heater wires or antenna. Use a cloth dampened with
lukewarm water to gently wipe the window clean. Wipe the window in strokes
running parallel to the heater wires or antenna.
●Be careful not to scratch or damage the heater wires or antenna.
Page 590 of 784
590
ES350_300h_OM_OM33B99U_(U)
7-3. Do-it-yourself maintenance
FuseAmpereCircuit
1WIP-S5Driver support system, windshield wipers
2FA N50Electric cooling fan
3H-LP CLN30No circuit
4ENG W/PMP*130Cooling system
5PTC HTR NO.250PTC heater
6PTC HTR NO.150PTC heater
7HTR50Air conditioning system
8ALT*2140Charging system
DC/DC*1120Hybrid system
9ABS NO.2*230VSC, ABS
10ST/AM2*230Starting system
ABS NO.1*130VSC, ABS
11H-LP-MAIN30H-LP RH-LO, H-LP LH-LO
12ABS MTR NO.2*150VSC, ABS
13ABS NO.1*250VSC, ABS
ABS MTR NO.1*150VSC, ABS
14R/B NO.2*150IGCT MAIN, INV W/PMP
15EPS80Electric power steering
16S-HORN7. 5S-HORN
17DEICER15Windshield wiper de-icer
18HORN10Horn
19TV15
Multi-information display, audio display,
Remote Touch, audio system, gauges and
meters
20AMP NO.230Audio system
21EFI NO.215
Multiport fuel injection system, sequential
multiport fuel system, electronic controlled
transmission
Page 591 of 784

ES350_300h_OM_OM33B99U_(U)
5917-3. Do-it-yourself maintenance
7
Maintenance and care
22EFI NO.3
10*2Multiport fuel injection system, sequential
multiport fuel system, air intake system,
exhaust system
7. 5*1Multiport fuel injection system, sequential
multiport fuel system, air intake system
23INJ7. 5Multiport fuel injection system, sequential
multiport fuel system
24ECU-IG2 NO.37. 5
Multiport fuel injection system, sequential
multiport fuel system, electronic controlled
transmission, power management system,
steering lock system, cruise control system
25IGN15Starting system
26D/L-AM225Power door lock system
27IG2-MAIN25INJ, IGN
28ALT-S*27. 5Charging system
DC/DC-S*17. 5Hybrid system
29MAYDAY5MAYDAY
30TURN&HAZ15Turn signal lights, emergency flashers
31STRG LOCK10Steering lock system
32AMP30Audio system
33H-LP LH-LO15Left-hand headlight
34H-LP RH-LO15Right-hand headlight
35EFI-MAIN NO.130EFI NO.2, EFI NO.3, fuel system
36SMART5Smart access system with push-button start,
occupant classification system
37ETCS10Multiport fuel injection system, sequential
multiport fuel system
38ABS NO.2*17. 5VSC, ABS
39EFI NO.17. 5
Multiport fuel injection system, sequential
multiport fuel system, electronic controlled
transmission
FuseAmpereCircuit
Page 592 of 784
592
ES350_300h_OM_OM33B99U_(U)
7-3. Do-it-yourself maintenance
*1:Hybrid vehicles
*2: Gasoline vehicles
40
A/F*220Air intake system
EFI-MAIN
NO.2
*120Fuel system, air intake system, exhaust sys-
tem
41AM27. 5Power management system, smart access
system with push-button start
42PA N E L10
Switch illumination, audio system, multi-infor-
mation display, audio display, shift lever light,
glove box light, console box light,
Remote Touch, intuitive parking assist switch
illumination
43DOME7. 5
Clock, footwell lights, vanity lights, ornament
lights, personal lights, door courtesy lights,
outer foot lights
44ECU-B NO.110
Smart access system with push-button start,
main body ECU, steering sensor, gauges and
meters, gateway ECU, electric tilt and tele-
scopic steering column, power seats, over-
head module, outside mirror control ECU,
power trunk opener and closer ECU
45SPARE25Spare fuse
46SPARE30Spare fuse
FuseAmpereCircuit
Page 594 of 784

594
ES350_300h_OM_OM33B99U_(U)
7-3. Do-it-yourself maintenance
■Driver’s side instrument panel
FuseAmpereCircuit
1ECU-IG1 NO.210
Main body ECU, audio system, shift lock sys-
tem, outside mirror control ECU, tension
reducer, windshield wipers, heated steering
wheel, multi-information display, audio dis-
play, intuitive parking assist, tire pressure
warning system, moon roof, auto anti-glare
inside rear view mirror, raindrop sensor, rear
sunshade, wireless door lock system, power
trunk opener and closer ECU
2ECU-IG1 NO.110
Electric cooling fan, windshield wiper de-
icer, VSC, ABS, charging system, steering
sensor, electronic controlled transmission,
electric power steering, gateway ECU, elec-
tric tilt and telescopic steering column
3PA N E L N O. 25Clock
4TA I L15Parking lights, side marker lights, license
plate lights
5DOOR F/R20Power window, outside mirror control ECU
6DOOR R/R20Po w e r w i n d o w
7DOOR F/L20Power window, outside mirror control ECU
8DOOR R/L20Po w e r w i n d o w
9H-LP LVL7. 5Automatic headlight leveling system
10WA S H E R10Windshield washer
11A/C-IG17. 5Air conditioning system, PTC heater, gauges
and meters, seat heaters and ventilators
Page 595 of 784

ES350_300h_OM_OM33B99U_(U)
5957-3. Do-it-yourself maintenance
7
Maintenance and care
12WIPER25Windshield wipers
13BKUP LP7. 5
Multiport fuel injection system, sequential
multiport fuel system, electronic controlled
transmission, audio system, navigation sys-
tem, back-up lights
14FUEL OPN10Fuel filler door opener
15EPS-IG110Electric power steering
16P/O U T L E T R R15Po w e r o u t l e t
17RADIO-ACC5Audio system, Remote Touch, multi-informa-
tion display, audio display, navigation system
18S/HTR&FAN F/R10Seat heaters and ventilators
19S/HTR&FAN F/L10Seat heaters and ventilators
20OBD7. 5On-Board diagnosis system
21ECU-B NO.210
Power window master switch, air condition-
ing system, smart access system with push-
button start, tire pressure warning system,
rear sunshade
22STRG HTR10Heated steering wheel
23PTL25Power trunk opener and closer ECU
24STOP7. 5
Power management system, multiport fuel
injection system, sequential multiport fuel
system, VSC, ABS, electronic controlled
transmission, driver support system, engine
room junction block assy, tail lights, high
mounted stoplight, smart access system with
push-button start, shift lock system
25P/ S E AT F/ L30Po w e r s e a t s
26A/C-B7. 5Air conditioning system
27S/ROOF10Moon roof
28P/ S E AT F/ R30Po w e r s e a t s
29PSB30Pre-collision seat belt
30D/L-AM120Main body ECU, power door lock system
FuseAmpereCircuit