Page 2 of 784

TABLE OF CONTENTS2
ES350_300h_OM_OM33B99U_(U)For your information ................................... 8
Reading this manual................................... 14
How to search ..............................................15
Pictorial index ............................................... 16
1-1. For safe use
Before driving................................. 28
For safety drive............................... 30
Seat belts .......................................... 32
SRS airbags ..................................... 38
Front passenger occupant classification system.................. 50
Safety information for children ....................................57
Child restraint systems ............... 58
Installing child restraints..............62
Exhaust gas precautions .............72
1-2. Hybrid system Hybrid system features (hybrid vehicles) ..........................73
Hybrid system precautions (hybrid vehicles) .......................... 77
1-3. Theft deterrent system Engine immobilizer system (gasoline vehicles) ..................... 84
Immobilizer system (hybrid vehicles) ......................... 86
Alarm .................................................88 2. Instrument cluster
Warning lights and indicators .............................. 92
Gauges and meters ......................97
Multi-information display ........ 102
Energy monitor/ consumption screen ................. 112
3-1. Key information Keys ................................................... 124
3-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start ............. 127
Wireless remote control ............ 141
Doors ................................................144
Trunk.................................................. 149
3-3. Adjusting the seats Front seats....................................... 157
Driving position memory..........159
Head restraints .............................165
3-4. Adjusting the steering wheel and mirrors
Steering wheel .............................. 169
Inside rear view mirror ............... 171
Outside rear view mirrors.........174
3-5. Opening, closing the windows and moon roof
Power windows............................. 177
Moon roof ........................................ 181
1For safety and security
2Instrument cluster
3Operation of each
component
Page 12 of 784

12
ES350_300h_OM_OM33B99U_(U)The SRS airbag and seat belt pretensioner devices in your Lexus contain explosive
chemicals. If the vehicle is scrapped with
the airbags and seat belt pretensioners left
as they are, this may cause an accident such as fire. Be sure to have the systems of
the SRS airbag and seat belt pretensioner removed and disposed of by a qualified
service shop or by your Lexus deal er before you scrap your vehicle.
Special handling may apply, See www.dt sc.ca.gov/hazardouswaste/perchlorate.
Your vehicle has components that may contain perchlorate. These components may
include airbag, seat belt pretensioners, and wireless remote control batteries.
Scrapping of your Lexus
Perchlorate Material
CAUTION
■General precautions while driving
Driving under the influence: Never drive your vehicle when under the influence of
alcohol or drugs that have impaired your ability to operate your vehicle. Alcohol
and certain drugs delay reaction time, impa ir judgment and reduce coordination,
which could lead to an accident that could result in death or serious injury.
Defensive driving: Always drive defensively. Anticipate mistakes that other drivers
or pedestrians might make and be ready to avoid accidents.
Driver distraction: Always give your full attention to driving. Anything that distracts
the driver, such as adjusting controls, ta lking on a cellular phone or reading can
result in a collision with resulting death or serious injury to you, your occupants or
others.
■General precaution regarding children’s safety
Never leave children unattended in the vehicle, and never allow children to have or
use the key.
Children may be able to start the vehicle or shift the vehicle into neutral. There is
also a danger that children may injure th emselves by playing with the windows, the
moon roof, or other features of the vehicle. In addition, heat build-up or extremely
cold temperatures inside the vehicle can be fatal to children.
Page 22 of 784

22Pictorial index
ES350_300h_OM_OM33B99U_(U)Audio remote control switches
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 357
Back switch
*1
Ta l k s w i t c h*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 431
Telephone switches
*1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 431
“DISP” button. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 103
Vehicle-to-vehicle distance button
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 261
Cruise control switch
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 254
Dynamic radar cruise control switch
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 258
LDA (Lane Departure Alert) switch
*2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 274
1
2
3
4
5
6
7
8
Page 23 of 784

23Pictorial index
ES350_300h_OM_OM33B99U_(U)Seat heater and ventilator switches
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 478
Heated steering wheel switch
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 478
Rear sunshade switch
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 495
Driving mode select switch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 311
EV drive mode switch
*3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 219
VSC OFF switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 315
Remote Touch
*1
Lexus Display Audio controller*2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 113, 352
*1: For vehicles with a navigation system, refer to “NAVIGATION SYSTEM OWNER’S MANUAL”.
*2: If equipped
*3: Hybrid vehicles
1
2
3
4
5
6
7
8
Page 88 of 784
881-3. Theft deterrent system
ES350_300h_OM_OM33B99U_(U)
Alarm
The alarm uses light and sound to give an alert when an intrusion is
detected.
The alarm is triggered in the following situations when the alarm is set:
●A locked door or trunk is unlocked or opened in any way other than
using the entry function, wireless remote control or mechanical key.
(The doors will lock again automatically.)
●The hood is opened.
Close the doors, trunk and hood,
and lock all the doors. The system
will be set automatically after 30
seconds.
The indicator light changes from
being on to flashing when the system
is set.
Do one of the following to deactivate or stop the alarms:
●Unlock the doors or open the trunk.
●Turn the “START STOP ENGINE” <“POWER”> switch to ACCES-
SORY or IGNITION ON mode, or start the engine
tem>. (The alarm will be deactivated or stopped after a few seconds.)
The alarm
Setting the alarm system
Deactivating or stopping the alarm
Page 113 of 784
ES350_300h_OM_OM33B99U_(U)
1132. Instrument cluster
2
Instrument cluster
Navigation system
“MENU” button
Remote Touch knob
For use of Remote Touch, refer to the
“NAVIGATION SYSTEM OWNER’S
MANUAL”.
Lexus Display Audio system
“MENU” button
Lexus Display Audio controller
(P. 3 5 2 )
Remote Touch/Lexus Display Audio controller
1
2
1
2
Page 114 of 784
114
ES350_300h_OM_OM33B99U_(U)
2. Instrument cluster
Navigation system screen
Press the “MENU” button on the
Remote Touch, then select “Info” on
the “Menu” screen, and then select
“Fuel Consumption”.
If the “Trip Information” or “Past
Record” screen is displayed, select
“Energy”.
Lexus Display Audio screen
Press the “MENU” button on the
Lexus Display Audio controller,
then select “Info” on the “Menu”
screen, and then select “Fuel Con-
sumption”.
If the “Energy Monitor” screen does
not appear, move the controller to the
right and select “Energy”.
Multi-information display
Press the “DISP” button on the steering wheel several times to select the
energy monitor display.
Energy monitor (hybrid vehicles)
Page 123 of 784
123
ES350_300h_OM_OM33B99U_(U)
3
Operation of
each component
3-1. Key information
Keys ................................................... 124
3-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start ............. 127
Wireless remote control ............ 141
Doors ................................................144
Trunk ..................................................149
3-3. Adjusting the seats Front seats .......................................157
Driving position memory ......... 159
Head restraints ............................ 165
3-4. Adjusting the steering wheel and mirrors
Steering wheel ..............................169
Inside rear view mirror................ 171
Outside rear view mirrors ........ 174
3-5. Opening, closing the windows and moon roof
Power windows ............................. 177
Moon roof ........................................181