Page 14 of 626
IS250C/350C_U
13
C
Seat heater/ventilator switches ∗ P. 372
Automatic transmission shift lever P. 151
Shift lock override button P. 526
Cigarette lighter ∗
Ashtray
∗
P. 370
P. 369
∗: If equipped
Auxiliary box ∗ P. 362
Page 15 of 626
IS250C/350C_U
14
Pictorial indexInstrument panel
Headlight switch Turn signal lever
Fog light switch P. 176
P. 158
P. 180
Shift paddle switches P. 155
Gauges and meters P. 161
Multi-information display P. 171
Windshield wiper and washer switch P. 182
Engine (ignition) switch P. 147
Trunk opener main switch P. 51
Tilt and telescopic steering control switch P. 76
Audio remote control switches *1P. 300
Horn P. 160Glove box P. 357
Parking brake pedal P. 159
Hood lock release lever P. 413
Inside door lock buttons P. 47
Page 19 of 626
IS250C/350C_U
18
Pictorial indexInstrument panel
D
Headlight cleaner switch ∗ P. 189
Trunk opener P. 51
Fuel filler door opener P. 95
Roof switch P. 86
Satellite switches P. 366
Instrument panel lightcontrol dial
P. 162
∗: If equipped
All window control switch P. 82
VSC off switch P. 216
Page 25 of 626

IS250C/350C_U
24
CAUTION
■General precautions while driving
Driving under the influence: Never drive your vehicle when under the influence of
alcohol or drugs that have impaired your ability to operate your vehicle. Alcohol
and certain drugs delay reaction time, impair judgment and reduce coordination,
which could lead to an accident that could result in death or serious injury.
Defensive driving: Always drive defensively. Anticipate mistakes that other drivers
or pedestrians might make and be ready to avoid accidents.
Driver distraction: Always give your full attention to driving. Anything that distracts
the driver, such as adjusting controls, talking on a cellular phone or reading can
result in a collision with resulting death or serious injury to you, your occupants or
others.
■General precaution regarding children’s safety
Never leave children unattended in the vehicle, and never allow children to have or
use the key.
Children may be able to start the vehicle or shift the vehicle into neutral. There is
also a danger that children may injure themselves by playing with the cigarette
lighter, the windows, the retractable hardtop, or other features of the vehicle. In
addition, heat build-up or extremely cold temperatures inside the vehicle can be
fatal to children.
Page 32 of 626

31
1-1. Key information
1
Before driving
IS250C/350C_U
NOTICE
■To prevent key damage
Observe the following.
●Do not drop the keys, subject them to strong shocks or bend them.
●Do not expose the keys to high temperatures for a long period of time.
●Do not get the keys wet or wash them in an ultrasonic washer etc.
●Do not attach metallic or magnetic materials to the keys or place the keys close to
such materials.
●Do not disassemble the electronic keys.
●Do not place the keys near objects that produce magnetic fields, such as TVs,
audio systems and induction cookers, or medical electrical equipment, such as
low-frequency therapy equipment.
■Precautions for handling the card keys
●Do not apply excess force when inserting the mechanical key to the card key.
Doing so may damage the card key.
●If the battery or card key terminals get wet, the battery may corrode and the card
key may stop working.
If the key is dropped into water, or if drinking water etc. is spilled on the key,
immediately remove the battery cover and wipe the battery and terminals. (To
remove the battery cover, lightly grasp it and pull.) If the battery is corroded, have
your Lexus dealer replace the battery.
●Do not crush the battery cover or use a screwdriver to remove the battery cover.
Forcibly removing the battery cover may bend or damage the key.
●If the battery cover is frequently removed, the battery cover may become loose.
●When installing the battery, make sure to check the direction of the battery.
Installing the battery in the wrong direction may cause the battery to deplete rap-
idly.
●The surface of the card key may be damaged, or its coating may peel off in the
following situations.
• The card key is carried together with hard objects, such as coins or keys.
• The card key is scraped with a sharp object, such as a tip of mechanical pencil.
• The surface of the card key is wiped with thinners or benzene.
Page 46 of 626
45
1-2. Opening, closing and locking the doors and trunk
1
Before driving
IS250C/350C_U
■Pa n i c m o d e
■Electronic key battery depletion
→P. 3 8
■Security feature
→P. 4 0
■When the electronic key battery is fully depleted
→P. 4 4 9
■Conditions affecting operation
→P. 3 6
■Customization that can be configured at Lexus dealer
Settings (e.g. trunk unlocking function) can be changed.
(Customizable features →P. 5 8 6 ) When is pushed for longer than about
one second, an alarm will sound for about 60
seconds and the vehicle lights will flash to
deter any person from trying to break into or
damage your vehicle.
To stop the alarm, push any button on the
wireless remote control.
Page 51 of 626

50
1-2. Opening, closing and locking the doors and trunk
IS250C/350C_U
■Side window open/close function linked to door operation
When a door is opened, its window opens slightly. When a door is closed, its win-
dow closes completely.
■Impact detection door lock release system
In the event that the vehicle is subject to a strong impact, both side doors are
unlocked. Depending on the force of the impact or the type of accident, however,
the system may not operate.
■Using the mechanical key
The doors can also be locked and unlocked with the mechanical key. (→P. 5 2 8 )
■Customization that can be configured at Lexus dealer
Settings (e.g. unlocking function using a key) can be changed.
(Customizable features →P. 5 8 6 )
CAUTION
■To prevent an accident
Observe the following precautions while driving the vehicle.
Failing to do so may result in a door opening and an occupant falling out, resulting in
death or serious injury.
●Always use a seat belt.
●Always lock both side doors.
●Ensure that both side doors are properly closed.
●Do not pull the inside handle of the doors while driving.
The doors may be opened and the passengers may be thrown out of the vehicle,
resulting in death or serious injury.
Page 53 of 626
52
1-2. Opening, closing and locking the doors and trunk
IS250C/350C_U
■Trunk light
When the trunk light switch is set to on, the trunk light turns on when the trunk is
opened.
■Tr u n k h a n d l e
■Internal trunk release lever
■Using the mechanical key
The trunk can be also opened using the mechanical key. (→P. 5 2 8 )
■When the retractable hardtop is operating
The trunk lid cannot be opened. Wait until the retractable hardtop is fully opened or
closed before opening the trunk lid. On
Off
Use the trunk handle when closing the trunk.
The trunk lid can be opened by pulling on the
glow-in-the-dark lever located on the inside
of the trunk lid.
The lever will continue to glow for some time
after the trunk lid is closed.