Page 2 of 588

TABLE OF CONTENTS2
IS250_EE(OM53C51E)
For your information ...................................8
Reading this manual .................................. 10
How to search................................................ 11
Pictorial index .............................................. 12
1-1. For safe use
Before driving ................................. 32
For safety drive ...............................34
Seat belts .......................................... 36
SRS airbags ...................................... 41
Airbag manual on-off
system ............................................. 52
Pop Up Hood..................................54
Safety information for
children........................................... 57
Child restraint systems............... 58
Installing child restraints ............. 67
Exhaust gas precautions .............76
1-2. Theft deterrent system
Engine immobilizer system ....... 77
Double locking system................82
Alarm .................................................832. Instrument cluster
Warning lights and
indicators .......................................90
Gauges and meters ..................... 95
Multi-information display.........100
Fuel consumption
information.................................. 106
3-1. Key information
Keys.....................................................112
3-2. Opening, closing and
locking the doors and trunk
Doors ................................................ 118
Trunk ................................................. 125
Smart entry & start system ...... 130
3-3. Adjusting the seats
Front seats .......................................147
Rear seats ....................................... 149
Driving position memory ...........151
Head restraints............................. 156
1For safety and security
2Instrument cluster
3Operation of
each component
Page 9 of 588

9
IS250_EE(OM53C51E)The SRS airbag and seat belt pretensioner devices in your Lexus contain explosive
chemicals. If the vehicle is scrapped with the airbags and seat belt pretensioners left as
they are, this may cause an accident such as fire. Be sure to have the systems of the SRS
airbag and seat belt pretensioner removed and disposed of by a qualified service shop or
by any authorized Lexus dealer or repairer, or another duly qualified and equipped pro-
fessional before you scrap your vehicle.
Scrapping of your Lexus
Your vehicle contains batteries and/or accumulators. Do not discard them into the
environment but cooperate with separate collection (Directive 2006/66/EC).
CAUTION
■General precautions while driving
Driving under the influence: Never drive your vehicle when under the influence of
alcohol or drugs that have impaired your ability to operate your vehicle. Alcohol and
certain drugs delay reaction time, impair judgment and reduce coordination, which
could lead to an accident that could result in death or serious injury.
Defensive driving: Always drive defensively. Anticipate mistakes that other drivers or
pedestrians might make and be ready to avoid accidents.
Driver distraction: Always give your full attention to driving. Anything that distracts the
driver, such as adjusting controls, talking on a cellular phone or reading can result in a
collision with resulting death or serious injury to you, your occupants or others.
■General precaution regarding children’s safety
Never leave children unattended in the vehicle, and never allow children to have or use
the key.
Children may be able to start the vehicle or shift the vehicle into neutral. There is also a
danger that children may injure themselves by playing with the windows, the moon
roof, or other features of the vehicle. In addition, heat build-up or extremely cold tem-
peratures inside the vehicle can be fatal to children.
Page 21 of 588

21Pictorial index
IS250_EE(OM53C51E)
Inside rear view mirror . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 161
Sun visors
*1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 398
Vanity mirrors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 398
Interior light . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 390
Personal lights
*2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 390
Moon roof switches
*3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 170
Intrusion sensor cancel switch
*3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 86
Intrusion sensor and tilt sensor cancel switch
*3. . . . . . . . . . . . . . . . . . . . . .P. 86
1
2
3
4
5
6
*1: NEVER use a rearward facing child re-
straint on a seat protected by an AC-
TIVE AIRBAG in front of it, DEATH or
SERIOUS INJURY to the CHILD can
occur. (→P. 74 )
*2: The illustration shows the front, but they are also equipped in the rear.
*3: If equipped
Page 29 of 588

29Pictorial index
IS250_EE(OM53C51E)
Inside rear view mirror . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 161
Sun visors
*1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 398
Vanity mirrors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 398
Interior light . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 390
Personal lights
*2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 390
Moon roof switches
*3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 170
Intrusion sensor cancel switch
*3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 86
Intrusion sensor and tilt sensor cancel switch
*3. . . . . . . . . . . . . . . . . . . . . .P. 86
1
2
3
4
5
6
*1: NEVER use a rearward facing child re-
straint on a seat protected by an AC-
TIVE AIRBAG in front of it, DEATH or
SERIOUS INJURY to the CHILD can
occur. (→P. 74 )
*2: The illustration shows the front, but they are also equipped in the rear.
*3: If equipped
Page 31 of 588
31
1For safety and security
IS250_EE(OM53C51E)
1-1. For safe use
Before driving................................. 32
For safety drive............................... 34
Seat belts .......................................... 36
SRS airbags .......................................41
Airbag manual on-off
system ............................................. 52
Pop Up Hood ................................. 54
Safety information for
children .......................................... 57
Child restraint systems ...............58
Installing child restraints..............67
Exhaust gas precautions ............. 76
1-2. Theft deterrent system
Engine immobilizer system ........77
Double locking system ............... 82
Alarm .................................................83
Page 34 of 588
341-1. For safe use
IS250_EE(OM53C51E)
Adjust the angle of the seatback so
that you are sitting straight up and so
that you do not have to lean forward
to steer. (→P. 1 4 7 )
Adjust the seat so that you can
depress the pedals fully and so that
your arms bend slightly at the elbow
when gripping the steering wheel.
(→P. 1 4 7 )
Lock the head restraint in place with the center of the head restraint closest to
the top of your ears. (→P. 1 5 6 )
Wear the seat belt correctly. (→P. 36)
Make sure that all occupants are wearing their seat belts before driving the vehi-
cle. (→P. 3 6 )
Use a child restraint system appropriate for the child until the child becomes
large enough to properly wear the vehicle’s seat belt. (→P. 5 8 )
For safety drive
For safe driving, adjust the seat and mirror to an appropriate position before
driving.
Correct driving posture
1
2
Correct use of the seat belts
3
4
Page 38 of 588

381-1. For safe use
IS250_EE(OM53C51E)
■After the rear center seat belt has been used
■Emergency locking retractor (ELR)
The retractor will lock the belt during a sudden stop or on impact. It may also lock if you
lean forward too quickly. A slow, easy motion will allow the belt to extend so that you can
move around fully.
■Child seat belt usage
The seat belts of your vehicle were principally designed for persons of adult size.
●Use a child restraint system appropriate for the child, until the child becomes large
enough to properly wear the vehicle’s seat belt. (→P. 5 8 )
●When the child becomes large enough to properly wear the vehicle’s seat belt, follow
the instructions regarding seat belt usage. (→P. 3 6 )
■Replacing the belt after the pretensioner has been activated
If the vehicle is involved in multiple collisions, the pretensioner will activate for the first
collision, but will not activate for the second or subsequent collisions.
■Seat belt regulations
If seat belt regulations exist in the country where you reside, please contact any autho-
rized Lexus dealer or repairer, or another duly qualified and equipped professional for
seat belt replacement or installation. Stow the buckle as shown.
Page 39 of 588

391-1. For safe use
1
For safety and security
IS250_EE(OM53C51E)
CAUTION
Observe the following precautions to reduce the risk of injury in the event of sudden
braking, sudden swerving or an accident.
Failure to do so may cause death or serious injury.
■Wearing a seat belt
●Ensure that all passengers wear a seat belt.
●Always wear a seat belt properly.
●Each seat belt should be used by one person only. Do not use a seat belt for more
than one person at once, including children.
●Lexus recommends that children be seated in the rear seat and always use a seat belt
and/or an appropriate child restraint system.
●To achieve a proper seating position, do not recline the seat more than necessary. The
seat belt is most effective when the occupants are sitting up straight and well back in
the seats.
●Do not wear the shoulder belt under your arm.
●Always wear your seat belt low and snug across your hips.
■Pregnant women
Obtain medical advice and wear the seat belt
in the proper way. (→P. 3 6 )
Women who are pregnant should position the
lap belt as low as possible over the hips in the
same manner as other occupants, extending
the shoulder belt completely over the shoulder
and avoiding belt contact with the rounding of
the abdominal area.
If the seat belt is not worn properly, not only the
pregnant woman, but also the fetus could suffer
death or serious injury as a result of sudden
braking or a collision.