Page 43 of 573

431-1. For safe use
1
For safety and security
IS350/250_U (OM53758U)
■If the SRS airbags deploy (inflate)
●Bruising and slight abrasions may result from contact with a deploying (inflating) SRS
airbag.
●A loud noise and white powder will be emitted.
●Parts of the airbag module (steering wheel hub, airbag cover and inflator) as well as the
seats, parts of the front and rear pillars, and roof side rails may be hot for several min-
utes. The airbag itself may also be hot.
●The windshield may crack.
●For Safety Connect subscribers, if the SRS airbags deploy or in the event of a severe
rear-end collision, the system is designed to send an emergency call to the response
center, notifying them of the vehicle’s location (without needing to push the “SOS” but-
ton) and an agent will attempt to speak wi th the occupants to ascertain the level of
emergency and assistance required. If the oc cupants are unable to communicate, the
agent automatically treats the call as an em ergency and helps to dispatch the necessary
emergency services. ( P. 3 7 8 )
CAUTION
■Modification and disposal of SRS airbag system components
Do not dispose of your vehicle or perform any of the following modifications without
consulting your Lexus dealer. The SRS airb ags may malfunction or deploy (inflate)
accidentally, causing de ath or serious injury.
●Installation, removal, disassembl y and repair of the SRS airbags
●Repairs, modifications, removal or replac ement of the steering wheel, instrument
panel, dashboard, seats or seat upholstery, fr ont, side and rear pillars or roof side rails
●Repairs or modifications of the front fender, front bumper, or side of the occupant
compartment
●Installation of snow plows, winches, etc. to the front grille (bull bars or kangaroo bar
etc.)
●Modifications to the vehicle’s suspension system
●Installation of electronic devices such as mobile two-way radios and CD players
●Modifications to your vehicle for a person with a physical disability
Page 46 of 573

461-1. For safe use
IS350/250_U (OM53758U)
■When to contact your Lexus dealer
In the following cases, the vehicle will require inspection and/or repair. Contact your
Lexus dealer as soon as possible.
●Any of the SRS airbags have been inflated.
●The front of the vehicle is damaged or
deformed, or was involv ed in an accident that
was not severe enough to cause the SRS front
airbags to inflate.
●A portion of a door or its surrounding area is
damaged or deformed, or the vehicle was
involved in an accident that was not severe
enough to cause the SRS side and curtain
shield airbags to inflate.
●The pad section of the steering wheel, dash-
board near the front passenger airbag or
lower portion of the instrument panel is
scratched, cracked, or otherwise damaged.
●The surface of the seats with the side airbag is
scratched, cracked, or otherwise damaged.
●The portion of the front pillars, rear pillars or
roof side rail garnishes (padding) containing
the curtain shield airbag s inside is scratched,
cracked, or otherwise damaged.
Page 52 of 573

521-1. For safe use
IS350/250_U (OM53758U)
CAUTION
■Front passenger occupant classification system precautions
●Do not recline the front passenger seatback so far that it touches the rear seat. This
may cause the “AIR BAG OFF” indicator light to be illuminated, which indicates that
the SRS airbags for the front passenger will not deploy in the event of a severe acci-
dent. If the seatback touches the rear seat, return the seatback to a position where it
does not touch the rear seat. Keep the fron t passenger seatback as upright as possi-
ble when the vehicle is moving. Reclining the seatback excessively may lessen the
effectiveness of the seat belt system.
●If an adult sits in the front passenger seat , the “AIR BAG ON” indicator light is illumi-
nated. If the “AIR BAG OFF” indicator is illuminated, ask the passenger to sit up
straight, well back in the seat, feet on the floor, and with the seat belt worn correctly. If
the “AIR BAG OFF” indicator still remains illuminated, either ask the passenger to
move to the rear seat, or if that is not possible, move the front passenger seat fully
rearward.
●When it is unavoidable to install a forward- facing child restraint system on the front
passenger seat, install the child restraint sy stem on the front passenger seat in the
proper order. ( P. 5 8 )
●Do not modify or remove the front seats.
●Do not kick the front passenger seat or subj ect it to severe impact. Otherwise, the
SRS warning light may come on to indicat e a malfunction of the front passenger
occupant classification system. In this ca se, contact your Lexus dealer immediately.
●Child restraint systems installed on the rear seat should not contact the front seat-
backs.
●Do not use a seat accessory, such as a cu shion and seat cover, that covers the seat
cushion surface.
●Do not modify or replace the upholstery of the front seat.
●Do not place anything between the cons ole box and front passenger seat. Other-
wise, the system may not detect the front passenger properly, leading to improper
operation of the airbags.
●Adjust the front passenger seat so that the head restraint does not touch the ceiling. If
the head restraint is left in contact with th e ceiling, the system may not detect the front
passenger properly, leading to im proper operation of the airbags.
Page 53 of 573

531-1. For safe use
1
For safety and security
IS350/250_U (OM53758U)
●It is recommended that children sit in the rear seats to avoid accidental con-
tact with the shift lever, wiper switch etc.
●Use the rear door child-protector lock or the window lock switch to avoid
children opening the door while driving or operating the power window acci-
dentally.
●Do not let small children operate equi pment which may catch or pinch body
parts, such as the power window, hood, trunk, seats etc.
Safety information for children
Observe the following precautions when children are in the vehicle.
Use a child restraint system appropriate for the child, until the child becomes
large enough to properly wear the vehicle’s seat belt.
CAUTION
Never leave children unattended in the vehicle, and never allow children to have or use
the key.
Children may be able to start the vehicle or sh ift the vehicle into neutral. There is also a
danger that children may injure themselves by playing with the windows, the moon roof
or other features of the vehicle. In additi on, heat build-up or extremely cold tempera-
tures inside the vehicle can be fatal to children.
Page 58 of 573
581-1. For safe use
IS350/250_U (OM53758U)
Child restraint LATCH anchors
LATCH anchors are provided for the
outboard rear seats, behind the anchor
covers.
Seat belts equipped with a child
restraint locking mechanism (ALR/
ELR belts except driver’s seat belt)
(P. 3 2 )
Anchor brackets (for top tether strap)
An anchor bracket is provided for each
rear seat.
Installing child restraints
Follow the child restraint system manu facturer’s instructions. Firmly secure
child restraints to the seats using the LATCH anchors or a seat belt. Attach the
top tether strap when installing a child restraint.
The lap/shoulder belt can be used if yo ur child restraint system is not compati-
ble with the LATCH (Lower Anchor s and Tethers for Children) system.
Page 98 of 573
97
Operation of
each component
3
IS350/250_U (OM53758U)
3-1. Key information
Keys ....................................................98
3-2. Opening, closing and locking the doors and trunk
Doors ............................................... 103
Trunk ................................................. 109
Smart access system with push-button start........................ 114
3-3. Adjusting the seats Front seats ...................................... 120
Rear seats ......................................... 121
Driving position memory ......... 123
Head restraints ............................. 127
3-4. Adjusting the steering wheel and mirrors
Steering wheel ............................. 130
Inside rear view mirror.............. 132
Outside rear view mirrors ....... 134
3-5. Opening, closing the windows and moon roof
Power windows ............................. 137
Moon roof ...................................... 140
Page 109 of 573
1083-2. Opening, closing and locking the doors and trunk
IS350/250_U (OM53758U)
CAUTION
■To prevent an accident
Observe the following precautions while driving the vehicle.
Failure to do so may result in a door opening and an occupant being thrown out of the
vehicle, resulting in death or serious injury.
●Ensure that all doors are properly closed and locked.
●Do not pull the inside handle of the doors while driving.
Be especially careful with the front doors, as the doors may be opened even if the
inside lock buttons ar e in locked position.
●Set the rear door child-protector locks when children are seated in the rear seats.
Page 111 of 573
1103-2. Opening, closing and locking the doors and trunk
IS350/250_U (OM53758U)
Using the trunk grip, lower the trunk
without applying force to the side and
push the trunk down from the outside
to close it.
To protect luggage stored in the trunk against theft, the luggage security system
can be set to on. Folding type rear seats only: Move
the luggage security system levers to
the lock position.
To disable the trunk opener, turn the
main switch in the glove box offOn
Off
When the main switch is off, the trunk
lid cannot be opened even with the
wireless remote control or entry
function.
When closing the trunk
Luggage security system
1
2
1
2