
IS350/250_U (OM53758U)
Pictorial indexSearch by illustration
1For safety
and securityMake sure to read through them
2Instrument clusterHow to read the gauges and meters, the variety of
warning lights and indicators, etc.
3Operation of each
componentOpening and closing the doors and windows,
adjustment before driving, etc.
4DrivingOperations and advices which are necessary for driving
5Lexus Display
Audio systemOperating the Lexus Display Audio system
6Interior featuresUsage of the interior features, etc.
7Maintenance
and careCaring for your vehicle and maintenance procedures
8When trouble
arisesWhat to do in case of malfunction or emergency
9Vehicle
specificationsVehicle specifications, customizable features, etc.
10For ownersReporting safety defects for U.S. owners, and seat belt
and SRS airbag instructio ns for Canadian owners
IndexSearch by symptom
Search alphabetically

TABLE OF CONTENTS6
IS350/250_U (OM53758U)
7-1. Maintenance and careCleaning and protecting the vehicle exterior ................ 384
Cleaning and protecting the vehicle inte rior.................. 387
7-2. Maintenance Maintenance requirements ............................ 390
General maintenance.............. 393
Emission inspection and maintenance (I/M)
programs .................................... 396
7-3. Do-it-yourself maintenance Do-it-yourself service precautions.................................397
Hood ............................................... 399
Positioning a floor jack.............400
Engine compartment ................ 401
Tires..................................................... 411
Tire inflation pressure ............... 420
Wheels ........................................... 423
Air conditioning filter ............... 425
Electronic key battery...............427
Checking and replacing fuses.............................................. 429
Light bulbs .................................... 432 8-1. Essential information
Emergency flashers .................. 446
If your vehicle has to be stopped in
an emergency ...........................447
8-2. Steps to take in an emergency
If your vehicle needs to be towed................................ 448
If you think something is wrong....................................... 453
Fuel pump shut off system ...... 454
If a warning light turns on or a warning buzzer
sounds ......................................... 455
If a warning message is displayed .................................. 461
If you have a flat tire ...................475
If the engine will not start ........ 485
If the shift lever cannot be shifted from P ..................... 487
If the electronic key does not operate properly .............488
If the vehicle battery is discharged............................. 490
If your vehicle overheats ......... 494
If the vehicle becomes stuck .............................................. 497
7Maintenance and care8When trouble arises

16Pictorial index
IS350/250_U (OM53758U)
■Instrument panel
Engine switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 1 5 9
Starting the engine/changing the modes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 159
Emergency stop of the engine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 447
When the engine will not start . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 485
Warning messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 471
Shift lever . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 164
Changing the shift position . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 164
Precautions against towing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 448
When the shift lever does not move . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 487
Meters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 81
Reading the meters/adjusting the instrument panel light . . . . . . . . . . . . . . . . . . P. 81
Warning lights/indicator lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 76
When the warning lights come on . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 455
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17Pictorial index
IS350/250_U (OM53758U)
Multi-information display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 86
Display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 86
When the warning messages are displayed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 461
Parking brake . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 172
Applying/releasing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 1 7 2
Precautions against winter season . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 255
Warning buzzer/message . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 461
Turn signal lever. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 170
Headlight switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 173
Headlights/parking lights/tail lights/daytime running lights . . . . . . . . . . . . . . P. 173
Fog lights
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 181
Windshield wiper and washer switch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Adding washer fluid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 410
Warning messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 468
Emergency flasher switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 446
Trunk opener. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 109
Hood lock release lever . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 399
Tilt and telescopic steering control switch
*1. . . . . . . . . . . . . . . . . . . . . . . . P. 130
Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 130
Driving position memory
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 123
Tilt and telescopic steering lock release lever*1. . . . . . . . . . . . . . . . . . . . P. 130
Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 130
Air conditioning system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 346
Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 346
Rear window defogger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 350
Audio system*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 260
Audio system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 260
Hands-free system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 311
Trunk opener main switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 110
*1: If equipped
*2: For vehicles with a navigation system, refer to “Navigation System Owner's Manual”.
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321-1. For safe use
IS350/250_U (OM53758U)
■After the rear center seat belt has been used
■Emergency locking retractor (ELR)
The retractor will lock the belt during a sudden stop or on impact. It may also lock if you
lean forward too quickly. A slow, easy motion w ill allow the belt to extend so that you can
move around fully.
■Automatic locking retractor (ALR)
When a passenger’s shoulder belt is completely extended and then retracted even
slightly, the belt is locked in that position an d cannot be extended. This feature is used to
hold a child restraint system (CRS) firmly. To fr ee the belt again, fully retract the belt and
then pull the belt out once more. ( P. 5 8 )
■Child seat belt usage
The seat belts of your vehicle were princi pally designed for persons of adult size.
●Use a child restraint system appropriate fo r the child, until the child becomes large
enough to properly wear the vehicle’s seat belt. ( P. 5 4 )
●When the child becomes large enough to properly wear the vehicle’s seat belt, follow
the instructions regardin g seat belt usage. (P. 3 0 )
■Replacing the belt after the pretensioner has been activated
If the vehicle is involved in multiple collisio ns, the pretensioner will activate for the first
collision, but will not activate for th e second or subsequent collisions.
■Seat belt extender Stow the buckle as shown.
If your seat belts cannot be fastened securely
because they are not long enough, a personal-
ized seat belt extender is available from your
Lexus dealer free of charge.

431-1. For safe use
1
For safety and security
IS350/250_U (OM53758U)
■If the SRS airbags deploy (inflate)
●Bruising and slight abrasions may result from contact with a deploying (inflating) SRS
airbag.
●A loud noise and white powder will be emitted.
●Parts of the airbag module (steering wheel hub, airbag cover and inflator) as well as the
seats, parts of the front and rear pillars, and roof side rails may be hot for several min-
utes. The airbag itself may also be hot.
●The windshield may crack.
●For Safety Connect subscribers, if the SRS airbags deploy or in the event of a severe
rear-end collision, the system is designed to send an emergency call to the response
center, notifying them of the vehicle’s location (without needing to push the “SOS” but-
ton) and an agent will attempt to speak wi th the occupants to ascertain the level of
emergency and assistance required. If the oc cupants are unable to communicate, the
agent automatically treats the call as an em ergency and helps to dispatch the necessary
emergency services. ( P. 3 7 8 )
CAUTION
■Modification and disposal of SRS airbag system components
Do not dispose of your vehicle or perform any of the following modifications without
consulting your Lexus dealer. The SRS airb ags may malfunction or deploy (inflate)
accidentally, causing de ath or serious injury.
●Installation, removal, disassembl y and repair of the SRS airbags
●Repairs, modifications, removal or replac ement of the steering wheel, instrument
panel, dashboard, seats or seat upholstery, fr ont, side and rear pillars or roof side rails
●Repairs or modifications of the front fender, front bumper, or side of the occupant
compartment
●Installation of snow plows, winches, etc. to the front grille (bull bars or kangaroo bar
etc.)
●Modifications to the vehicle’s suspension system
●Installation of electronic devices such as mobile two-way radios and CD players
●Modifications to your vehicle for a person with a physical disability

1043-2. Opening, closing and locking the doors and trunk
IS350/250_U (OM53758U)
■Operation signals
A buzzer sounds and the emergency flashers flash to indicate that the doors have been
locked/unlocked. (Locked: once; Unlocked: twice)
A buzzer sounds to indicate that the windows and moon roof are operating.
■Security feature
If a door is not opened within approximately 60 seconds after the vehicle is unlocked, the
security feature automatically locks the vehicle again.
■Welcome light illumination control
The front position, tail and license plate lights automatically turn on at night when the
doors are unlocked using the entry function or wireless remote control if the light switch
is in the “AUTO” position.
■When the door cannot be locked by the lock sensor on the upper part of the door han-
dle
■Door lock buzzer
If an attempt to lock the doors is made when a door is not fully closed, a buzzer sounds
continuously for 5 seconds. Fully close the door to stop the buzzer, and lock the vehicle
once more.
■Setting the alarm
Locking the doors will set the alarm system. ( P. 7 1 )
■If the smart access system with push-butto n start or the wireless remote control does
not operate properly
Use the mechanical key to lock and unlock the doors. ( P. 4 8 8 )
Replace the key battery with a new one if it is depleted. ( P. 4 2 7 )
If the door will not lock even when the topside
sensor area is touched, try touching both the
topside and underside sensor areas at the same
time.

1484-1. Before driving
IS350/250_U (OM53758U)
CAUTION
Observe the following precautions.
Failure to do so may result in death or serious injury.
■When starting the vehicle
Always keep your foot on the brake pedal while stopped with the engine running. This
prevents the vehicle from creeping.
■When driving the vehicle
●Do not drive if you are unfamiliar with the location of the brake and accelerator ped-
als to avoid depressing the wrong pedal.
• Accidentally depressing th e accelerator pedal instead of the brake pedal will
result in sudden acceleration that may lead to an accident.
• When backing up, you may twist your body around, leading to a difficulty in oper-
ating the pedals. Make sure to operate the pedals properly.
• Make sure to keep a correct driving posture even when moving the vehicle only slightly. This allows you to depress th e brake and accelerator pedals properly.
• Depress the brake pedal using your righ t foot. Depressing the brake pedal using
your left foot may delay response in an emergency, resulting in an accident.
●Do not drive the vehicle over or stop the vehicle near flammable materials.
The exhaust system and exhaust gases can be extremely hot. These hot parts may
cause a fire if there is any flammable material nearby.
●During normal driving, do not turn off the engine. Turning the engine off while driving
will not cause loss of steering or braking co ntrol, but the power assist to these systems
will be lost. This will make it more difficul t to steer and brake, so you should pull over
and stop the vehicle as soon as it is safe to do so.
However, in the event of an emergency, such as if it becomes impossible to stop the
vehicle in the normal way: P. 4 4 7
●Use engine braking (downshift) to maintain a safe speed when driving down a steep
hill.
Using the brakes continuously may cause th e brakes to overheat and lose effective-
ness. ( P. 1 6 4 )
●Do not adjust the positions of the steering wh eel, the seat, or the inside or outside rear
view mirrors while driving.
Doing so may result in a loss of vehicle control.
●Always check that all passengers’ arms, heads or other parts of their body are not
outside the vehicle.
●Do not drive in excess of the speed limit. Ev en if the legal speed limit permits it, do not
drive over 85 mph (140 km/h) unless your vehicle has high-speed capability tires.
Driving over 85 mph (140 km/h) may result in tire failure, loss of control and possible
injury. Be sure to consult a tire dealer to determine whether the tires on your vehicle
are high-speed capability tires or not before driving at such speeds.