
3
1
9 8
7 5 4
3
2
IS350/250_U (OM53758U)
6
4-1. Before drivingDriving the vehicle ......................146
Cargo and luggage.....................153
Vehicle load limits ........................156
Trailer towing ................................. 157
Dinghy towing .............................. 158
4-2. Driving procedures Engine (ign ition) switch .............159
Automatic transmission ............164
Turn signal lever ............................ 170
Parking brake ................................ 172
4-3. Operating the lights and wipers
Headlight switch .......................... 173
Automatic High Beam............... 176
Fog light switch .............................. 181
Windshield wipers and washer .......................................... 182
4-4. Refueling Opening the fuel tank cap ...... 188 4-5. Using the driving support
systems
Cruise control ...............................192
Dynamic radar cruise control ...........................................196
LDA (Lane Departure Alert)........208
Intuitive parking assist ................ 214
Rear view monito r system ........ 221
Driving mode select switch .............................................231
Driving assist systems .............. 234
PCS (Pre-Collision System) ......... 240
BSM (Blind Spot Monitor) ..............246
• The Blind Spot Monitor function .....................................249
• The Rear Cross Traffic Alert function ..........................251
4-6. Driving tips Winter driving tips ..................... 254
4Driving

15Pictorial index
IS350/250_U (OM53758U)
Windshield wipers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Precautions against winter season . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 254
To prevent freezing (windshield wiper de-icer)
* . . . . . . . . . . . . . . . . . . . . . . . P. 350
Precautions against car wash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 385
Fuel filler door . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 1 8 8
Refueling method . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 188
Fuel type/fuel tank capacity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 502
Tires . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 411
Tire size/inflation pressure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 507
Winter tires/tire chain. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 254
Checking/rotation/tire pressure warning system . . . . . . . . . . . . . . . . . . . . . . . . . P. 411
Coping with flat tires . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 475
Hood . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 399
Opening. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 399
Engine oil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 502
Coping with overheat . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 494
Warning messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 46 3
Headlights/parking lights/daytime running lights . . . . . . . . . . . . . . . . . . . P. 173
Fog lights
* . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 181
Turn signal lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 170
Tail lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 173
Stop lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 146
License plate lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 17 3
Back-up lights
Shifting the shift lever to R . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 16 4
Side marker lights . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 173
4
5
6
7
Light bulbs of the exterior lights for driving(Replacing method: P. 432, Watts: P. 509)
*: If equipped
8
9
10
11
12
13
14
15

17Pictorial index
IS350/250_U (OM53758U)
Multi-information display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 86
Display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 86
When the warning messages are displayed . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 461
Parking brake . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 172
Applying/releasing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 1 7 2
Precautions against winter season . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 255
Warning buzzer/message . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 461
Turn signal lever. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 170
Headlight switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 173
Headlights/parking lights/tail lights/daytime running lights . . . . . . . . . . . . . . P. 173
Fog lights
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 181
Windshield wiper and washer switch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 182
Adding washer fluid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 410
Warning messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 468
Emergency flasher switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 446
Trunk opener. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 109
Hood lock release lever . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 399
Tilt and telescopic steering control switch
*1. . . . . . . . . . . . . . . . . . . . . . . . P. 130
Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 130
Driving position memory
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 123
Tilt and telescopic steering lock release lever*1. . . . . . . . . . . . . . . . . . . . P. 130
Adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 130
Air conditioning system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 346
Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 346
Rear window defogger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 350
Audio system*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 260
Audio system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 260
Hands-free system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P . 311
Trunk opener main switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 110
*1: If equipped
*2: For vehicles with a navigation system, refer to “Navigation System Owner's Manual”.
4
5
6
7
8
9
10
11
12
13
14
15

18Pictorial index
IS350/250_U (OM53758U)
■Switches
Automatic high beam switch*1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 176
Windshield wiper de-icer switch
*1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 350
Odometer/trip meter and trip meter reset button . . . . . . . . . . . . . . . . . . P. 83
Instrument panel light control swit ches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 84
Rear sunshade switch
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 367
Intuitive parking assist switch
*1, 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 214
BSM (Blind Spot Monitor) main switch
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 246
1
2
3
4
5
6
7

411-1. For safe use
1
For safety and security
IS350/250_U (OM53758U)
CAUTION
■SRS airbag precautions
●Do not allow a child to stand in front of the
SRS front passenger airbag unit or sit on the
knees of a front passenger.
●Do not allow the front seat occupants to hold
items on their knees.
●Do not lean against the door, the roof side rail
or the front, side and rear pillars.
●Do not allow anyone to kneel on the passen-
ger seats toward the door or put their head or
hands outside the vehicle.
●Do not attach anything to or lean anything
against areas such as the dashboard, steering
wheel pad and lower portion of the instru-
ment panel.
These items can become projectiles when the
SRS driver, front passenger and knee airbags
deploy.
●Do not attach anything to areas such as a
door, windshield glass, side door glass, front
or rear pillar, roof side rail and assist grip.

431-1. For safe use
1
For safety and security
IS350/250_U (OM53758U)
■If the SRS airbags deploy (inflate)
●Bruising and slight abrasions may result from contact with a deploying (inflating) SRS
airbag.
●A loud noise and white powder will be emitted.
●Parts of the airbag module (steering wheel hub, airbag cover and inflator) as well as the
seats, parts of the front and rear pillars, and roof side rails may be hot for several min-
utes. The airbag itself may also be hot.
●The windshield may crack.
●For Safety Connect subscribers, if the SRS airbags deploy or in the event of a severe
rear-end collision, the system is designed to send an emergency call to the response
center, notifying them of the vehicle’s location (without needing to push the “SOS” but-
ton) and an agent will attempt to speak wi th the occupants to ascertain the level of
emergency and assistance required. If the oc cupants are unable to communicate, the
agent automatically treats the call as an em ergency and helps to dispatch the necessary
emergency services. ( P. 3 7 8 )
CAUTION
■Modification and disposal of SRS airbag system components
Do not dispose of your vehicle or perform any of the following modifications without
consulting your Lexus dealer. The SRS airb ags may malfunction or deploy (inflate)
accidentally, causing de ath or serious injury.
●Installation, removal, disassembl y and repair of the SRS airbags
●Repairs, modifications, removal or replac ement of the steering wheel, instrument
panel, dashboard, seats or seat upholstery, fr ont, side and rear pillars or roof side rails
●Repairs or modifications of the front fender, front bumper, or side of the occupant
compartment
●Installation of snow plows, winches, etc. to the front grille (bull bars or kangaroo bar
etc.)
●Modifications to the vehicle’s suspension system
●Installation of electronic devices such as mobile two-way radios and CD players
●Modifications to your vehicle for a person with a physical disability

561-1. For safe use
IS350/250_U (OM53758U)
CAUTION
■Child restraint precautions
●For effective protection in automobile accidents and sudden stops, a child must be
properly restrained, using a se at belt or child restraint system depending on the age
and size of the child. Holding a child in your arms is not a substitute for a child restraint
system. In an accident, the child can be crushed against the windshield, or between
you and the vehicle’s interior. This may cause death or serious injury to the child in the
event of a sudden stop, sudden swerve or an accident.
●Lexus strongly urges the use of a proper child restraint system that conforms to the
size of the child, installed on the rear seat . According to accident statistics, the child is
safer when properly restrained in th e rear seat than in the front seat.
●Never install a rear-facing child restraint system on the front passenger seat even if
the “AIR BAG OFF” indicator light is illuminated.
In the event of an accident, the force of the rapid inflation of the front passenger air-
bag can cause death or serious injury to the child if the rear-facing child restraint sys-
tem is installed on the front passenger seat.
●A forward-facing child restraint system ma y be installed on the front passenger seat
only when it is unavoidable. A child restra int system that requires a top tether strap
should not be used in the front passenger seat since there is no top tether strap
anchor for the front passenger seat. Adjust the seatback as upright as possible and
always move the seat as far back as possible even if the “AIR BAG OFF” indicator
light is illuminated, because the front passenger airbag could inflate with considerable
speed and force. Otherwise, the child may be killed or seriously injured.
●Do not use the seat belt extender when inst alling a child restraint system on the front
or rear passenger seat. If installing a child restraint system with the seat belt extender
connected to the seat belt, the seat belt w ill not securely hold the child restraint sys-
tem, which could cause death or serious injury to the child or other passengers in the
event of a sudden stop, sudden swerve or accident.
●Do not allow the child to lean his/her head or any part of his/her body against the
door or the area of th e seat, front, center and rear pill ars or roof side rails from which
the SRS side airbags or SRS curtain shield ai rbags deploy even if the child is seated in
the child restraint system. It is dangerous if the SRS side airbags and curtain shield air-
bags inflate, and the impact could caus e death or serious injury to the child.
●Make sure you have complied with all insta llation instructions provided by the child
restraint manufacturer and that the system is properly secured. If it is not secured
properly, it may cause death or serious inju ry to the child in the event of a sudden
stop, sudden swerve or an accident.

892. Instrument cluster
2
Instrument cluster
IS350/250_U (OM53758U)
■Pop-up display
Select to set the following pop-up displays, which may appear in some situa-
tions, on/off. • Route guidance display of the navigation system-linked system (if equipped)
• Incoming call display of the hands-free phone system
• Windshield wiper switch operation display (if equipped)
• Headlight switch operation display (if equipped)
• Dynamic radar cruise control operation display (if equipped)
• Instrument panel brightness adjustment display
• Main meter switch operation display (F SPORT models)
■Accent color (except F SPORT models)
Select to change the accent colors on the screen, such as the cursor color.
■Needle (F SPORT models)
Select to change the needle color for the tachometer.
■Speed indicator (F SPORT models)
Select to set the speed indicator on/
off.
When set to on, both sides of the dis-
played speed unit will turn yellow
when the vehicle reaches a set
speed.
Selectable speed range:
30 mph to 100 mph (50 km/h to
160 km/h)
*
The indicator will illuminate in yellow at an optionally set speed and red at the fixed
high speed.
*: Always observe the legal speed limit when driving on public roads.
■Rev indicator (F SPORT models)
Select to set the rev indicator on/off.
When set to on, the tachometer will
show a ring-shaped indicator in red
when the engine reaches a set speed.
Selectable engine speed range:
2000 rpm to 6600 rpm.