Page 2 of 908

TABLE OF CONTENTS2
ES350 300h_OM_OM33A01U_(U)For your information ................................... 8
Reading this manual................................... 14
How to search ..............................................15
Pictorial index ...............................................16
1-1. For safe use
Before driving................................. 28
For safety drive............................... 30
Seat belts .......................................... 32
SRS airbags ..................................... 38
Front passenger occupant classification system.................. 49
Safety information for children ................................... 54
Child restraint systems ............... 55
Installing child restraints............. 59
Exhaust gas precautions ............ 69
1-2. Hybrid system Hybrid system features (hybrid vehicles) ......................... 70
Hybrid system precautions (hybrid vehicles) .......................... 74
1-3. Theft deterrent system Engine immobilizer system (gasoline vehicles) ..................... 80
Immobilizer system (hybrid vehicles) ......................... 82
Alarm ................................................. 84 2. Instrument cluster
Warning lights and indicators .............................. 88
Gauges and meters ..................... 93
Multi-information display .......... 98
Energy monitor/ consumption screen ............... 108
3-1. Key information Keys ...................................................120
3-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start .............123
Wireless remote control ...........136
Doors ................................................139
Trunk..................................................144
3-3. Adjusting the seats Front seats........................................ 151
Driving position memory..........153
Head restraints .............................159
3-4. Adjusting the steering wheel and mirrors
Steering wheel .............................. 162
Inside rear view mirror ..............164
Outside rear view mirrors........ 167
3-5. Opening, closing the windows and moon roof
Power windows............................. 170
Moon roof ....................................... 173
1For safety and security
2Instrument cluster
3Operation of each
component
Page 12 of 908

12
ES350 300h_OM_OM33A01U_(U)The SRS airbag and seat belt pretensioner devices in your Lexus contain explosive
chemicals. If the vehicle is scrapped with
the airbags and seat belt pretensioners left
as they are, this may cause an accident such as fire. Be sure to have the systems of
the SRS airbag and seat belt pretensioner removed and disposed of by a qualified
service shop or by your Lexus deal er before you scrap your vehicle.
Special handling may apply, See www.dt sc.ca.gov/hazardouswaste/perchlorate.
Your vehicle has components that may contain perchlorate. These components may
include airbag, seat belt pretensioners, and wireless remote control batteries.
Scrapping of your Lexus
Perchlorate Material
CAUTION
■General precautions while driving
Driving under the influence: Never drive your vehicle when under the influence of
alcohol or drugs that have impaired your ability to operate your vehicle. Alcohol
and certain drugs delay reaction time, impa ir judgment and reduce coordination,
which could lead to an accident that could result in death or serious injury.
Defensive driving: Always drive defensively. Anticipate mistakes that other drivers
or pedestrians might make and be ready to avoid accidents.
Driver distraction: Always give your full attention to driving. Anything that distracts
the driver, such as adjusting controls, ta lking on a cellular phone or reading can
result in a collision with resulting death or serious injury to you, your occupants or
others.
Page 22 of 908

22Pictorial index
ES350 300h_OM_OM33A01U_(U)Audio remote control switches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 441, 565
Back switch
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 444
Ta l k s w i t c h
*1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 444, 574
Telephone switches
*1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 444, 574
“DISP” button. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 99
Vehicle-to-vehicle distance button
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .P. 251
Cruise control switch
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 244
Dynamic radar cruise control switch
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 248
Tilt and telescopic steering control switch
*2 . . . . . . . . . . . . . . . . . . . . . . . . P. 162
LDA (Lane Departure Alert) switch
*2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 264
1
2
3
4
5
6
7
8
9
Page 23 of 908

23Pictorial index
ES350 300h_OM_OM33A01U_(U)Seat heater switches
*2/seat heater and ventilator switches*2. . . . P. 620
Heated steering wheel switch
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 618
Rear sunshade switch
*2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 623
Driving mode select switch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 296
EV drive mode switch
*3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 211
VSC OFF switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 300
Remote Touch
*1, 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 109
Lexus Display Audio controller
*2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . P. 109, 334
*1: Refer to “Navigation System Owner’s Manual”.
*2: If equipped
*3: Hybrid vehicles
1
2
3
4
5
6
7
8
Page 84 of 908
841-3. Theft deterrent system
ES350 300h_OM_OM33A01U_(U)
Alarm
The alarm uses light and sound to give an alert when an intrusion is
detected.
The alarm is triggered in the following situations when the alarm is set:
●A locked door or trunk is unlocked or opened in any way other than
using the entry function, wireless remote control or mechanical key.
(The doors will lock again automatically.)
●The hood is opened.
Close the doors, trunk and hood,
and lock all the doors. The system
will be set automatically after 30
seconds.
The indicator light changes from
being on to flashing when the system
is set.
Do one of the following to deactivate or stop the alarms:
●Unlock the doors or open the trunk.
●Turn the “START STOP ENGINE” <“POWER”> switch to ACCES-
SORY or IGNITION ON mode, or start the engine
tem>. (The alarm will be deactivated or stopped after a few seconds.)
The alarm
Setting the alarm system
Deactivating or stopping the alarm
Page 109 of 908
ES350 300h_OM_OM33A01U_(U)
1092. Instrument cluster
2
Instrument cluster
Navigation system
Remote Touch
*
“MENU” button
Remote Touch knob
*: For use of the Remote Touch, refer to the “Navigation System Owner’s
Manual”.
Lexus Display Audio system
Lexus Display Audio controller
( P. 3 3 4 )
“MENU” button
Displaying the “MENU” screen
Lexus Display Audio controller
Turn or move the controller in the four
direction to select a function, number
and screen button.
Push the controller to enter the
selected function, number and screen
button.
Remote Touch/Lexus Display Au dio controller (if equipped)
1
2
1
2
Page 110 of 908
110
ES350 300h_OM_OM33A01U_(U)
2. Instrument cluster
■Navigation system screen or Lexus Display Audio system screen (if
equipped)
Vehicles with a navigation system
Press the “MENU” button on the Remote Touch.
Select “Info/Apps” on the
“Menu” screen.
Select “Fuel Consumption” on
the “Information” screen.
If the “Energy Monitor” screen
is not displayed, select
“Energy”.
Vehicles with Lexus Display Audio system
Press the “MENU” button on the Lexus Display Audio controller.
Select “Car” on the “Menu”
screen.
If the “Energy Monitor” screen
is not displayed, select
“Energy”.
Energy monitor (hybrid vehicles)
1
2
3
1
2
Page 115 of 908
ES350 300h_OM_OM33A01U_(U)
1152. Instrument cluster
2
Instrument cluster
Vehicles with a navigation system
Press the “MENU” button on the Remote Touch, then select “Info/
Apps” on the “Menu” screen.
Select “Fuel Consumption” on the “Information” screen.
Hybrid vehicles: If the “Energy Monitor” screen is displayed, select
“Fuel Consumption”.
Vehicles with Lexus Display Audio system
Press the “MENU” button on the Le xus Display Audio controller, then
select “Car” on the “Menu” screen.
Hybrid vehicles: If the “Energy Mo nitor” screen is displayed, select
“Fuel Consumption”.
Consumption (if equipped)
1
2