Page 3 of 554

TABLE OF CONTENTSIndex
2
ES350_U
1-1. Key informationKeys ...................................................... 26
1-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start .......................... 28
Wireless remote control .............. 40
Doors.................................................... 42
Trunk..................................................... 46
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats ......................................... 50
Driving position memory .............. 51
Seat position memory ................... 55
Head restraints................................. 57
Seat belts ............................................ 59
Steering wheel.................................. 65
Anti-glare inside rear view mirror ................................................ 66
Outside rear view mirrors ........... 68 1-4. Opening and closing the
windows and moon roof
Power windows................................ 70
Moon roof .......................................... 73
1-5. Refueling Opening the fuel tank cap........... 78
1-6. Theft deterrent system Engine immobilizer system .......... 81
Alarm.................................................... 83
1-7. Safety information Correct driving posture ............... 86
SRS airbags ...................................... 88
Front passenger occupant classification system .................... 99
Child restraint systems ............... 104
Installing child restraints ............. 108
1Before driving
For vehicles with a navigation system, refer to the “Navigation System Owner’s
Manual” for information regarding the equipment listed below.
• Navigation system
• Air conditioning
• Rear view monitor system • Audio/video system
•Climate control
• Intuitive parking assist
Page 6 of 554

1
2
3
4
5
6
7
5
ES350_U
4-1. Maintenance and careCleaning and protecting the vehicle exterior.................. 358
Cleaning and protecting the vehicle interior ..................... 361
4-2. Maintenance Maintenance requirements ..... 364
General maintenance ................ 366
Emission inspection and maintenance (I/M)
programs ...................................... 369
4-3. Do-it-yourself maintenance Do-it-yourself service precautions .................................. 370
Hood.................................................. 374
Positioning a floor jack............... 375
Engine compartment.................. 377
Tires .................................................. 390
Tire inflation pressure................. 399
Wheels............................................. 403
Air conditioning filter................. 405
Electronic key battery ................ 407
Checking and replacing fuses ............................................... 409
Headlight aim ................................. 418
Light bulbs ....................................... 420 5-1. Essential information
Emergency flashers ................... 430
If your vehicle needs to be towed .............................................. 431
If you think something is wrong ............................................. 437
Fuel pump shut off system ....... 438
5-2. Steps to take in an emergency If a warning light turns on or a warning buzzer
sounds... ........................................ 439
If a warning message is displayed....................................... 449
If you have a flat tire...................... 461
If the engine will not start .......... 470
If the shift lever cannot be shifted from P .............................. 472
If you lose your keys .................... 473
If the electronic key does not operate properly ............... 474
If the vehicle battery is discharged ................................... 477
If your vehicle overheats .......... 480
If the vehicle becomes stuck............................................... 483
If your vehicle has to be stopped in an emergency ...... 484
4Maintenance and care5When trouble arises
Page 7 of 554
TABLE OF CONTENTSIndex
6
ES350_U
6-1. SpecificationsMaintenance data (fuel, oil level, etc.).................... 486
Fuel information ............................ 496
Tire information............................. 499
6-2. Customization Customizable features.................. 511
6-3. Initialization Items to initialize ............................ 519
Reporting safety defects for U.S. owners........................... 522
Seat belt instructions for Canadian owners
(in French) .................................... 523
SRS airbag instructions for Canadian owners
(in French) .................................... 525 Abbreviation list ................................... 536
Alphabetical index ............................. 538
What to do if... ...................................... 550
6Vehicle specifications
7For owners
Index
Page 10 of 554
ES350_U
9
Tires
●Rotation
● Replacement
● Inflation pressure
P. 390
P. 461
P. 493
Tail lights P. 149
Side marker lights P. 149
Trunk P. 46
Rear window defogger P. 213
Doors P. 42
Fuel filler door P. 78
Turn signal lights P. 135
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ES350_U
17
C
Rear sunshade
switch
∗ P. 333
Intuitive parking assist
switch
∗ *1P. 176
Instrument panel light
control
P. 139
Outside rear view mirror switch P. 68
Auxiliary box P. 321
Type A
Type B
Trunk opener P. 46
Fuel filler door opener P. 78
Rear sunshade
switch
∗ P. 333
Instrument panel light
control
P. 139
Outside rear view mirror switch P. 68
Auxiliary box P. 321
Trunk opener P. 46
Fuel filler door opener P. 78
VSC off switch P. 183
VSC off switch P. 183
∗: If equipped
*1: For vehicles with a navigation system, refer to the “Navigation System Owner’s Manual”.
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ES350_U
18
For your information
Main Owner’s Manual
Please note that this manual applies to all models and explains all equipment, includ-
ing options. Therefore, you may find some explanations for equipment not installed
on your vehicle.
All specifications provided in this manual are current at the time of printing. How-
ever, because of the Lexus policy of continual product improvement, we reserve the
right to make changes at any time without notice.
Depending on specifications, the vehicle shown in the illustration may differ from
your vehicle in terms of color and equipment.
Noise from under vehicle after turning off the engine
Approximately five hours after the engine is turned off, you may hear sound coming
from under the vehicle for several minutes. This is the sound of a fuel evaporation
leakage check and, it does not indicate a malfunction.
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ES350_U
19
Accessories, spare parts and modification of your Lexus
A wide variety of non-genuine spare parts and accessories for Lexus vehicles are
currently available in the market. You should know that Toyota does not warrant
these products and is not responsible for their performance, repair, or replacement,
or for any damage they may cause to, or adverse effect they may have on, your
Lexus vehicle.
This vehicle should not be modified with non-genuine Lexus products. Modification
with non-genuine Lexus products could affect its performance, safety or durability,
and may even violate governmental regulations. In addition, damage or perfor-
mance problems resulting from the modification may not be covered under war-
ranty.
Installation of a mobile two-way radio system
The installation of a mobile two-way radio system in your vehicle could affect elec-
tronic systems such as:
●Multiport fuel injection system/sequential multiport fuel injection system
●Cruise control system
●Anti-lock brake system
●SRS airbag system
●Seat belt pretensioner system
Be sure to check with your Lexus dealer for precautionary measures or special
instructions regarding installation of a mobile two-way radio system.
Page 26 of 554

Before driving1
25
ES350_U
1-1. Key informationKeys ............................................... 26
1-2. Opening, closing and locking the doors
and trunk
Smart access system with push-button start ................... 28
Wireless remote control ........ 40
Doors ............................................ 42
Trunk ............................................. 46
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats .................................. 50
Driving position memory ......... 51
Seat position memory.............. 55
Head restraints .......................... 57
Seat belts ..................................... 59
Steering wheel........................... 65
Anti-glare inside rear view mirror ......................................... 66
Outside rear view mirrors ...... 68 1-4. Opening and closing the
windows and moon roof
Power windows .......................... 70
Moon roof ................................... 73
1-5. Refueling Opening the fuel tank cap ..... 78
1-6. Theft deterrent system Engine immobilizer system..... 81
Alarm............................................ 83
1-7. Safety information Correct driving posture ......... 86
SRS airbags ................................ 88
Front passenger occupant classification system.............. 99
Child restraint systems ......... 104
Installing child restraints....... 108