
TABLE OF CONTENTSIndex
IS350/250_U
2
1-1. Key informationKeys ...................................................... 24
1-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start .......................... 28
Wireless remote control .............. 40
Doors.................................................... 43
Trunk..................................................... 47
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats ........................................... 51
Driving position memory (driver’s seat) ................................. 53
Head restraints................................. 57
Seat belts ............................................ 60
Steering wheel (manually adjustable type)............................. 67
Steering wheel (power-adjustable type)............ 68
Anti-glare inside rear view mirror ................................................ 70
Outside rear view mirrors ........... 72 1-4. Opening and closing the
windows and moon roof
Power windows................................ 75
Moon roof .......................................... 78
1-5. Refueling Opening the fuel tank cap........... 82
1-6. Theft deterrent system Engine immobilizer system ........ 85
Alarm.................................................... 87
Theft prevention labels (U.S.A.) ............................................. 90
1-7. Safety information Correct driving posture ................ 91
SRS airbags ....................................... 93
Front passenger occupant classification system .................. 104
Child restraint systems ............... 109
Installing child restraints ............... 113
1Before driving

TABLE OF CONTENTSIndex
IS350/250_U
6
5-1. Essential informationEmergency flashers.................... 450
If your vehicle needs to be towed............................................... 451
If you think something is wrong ............................................. 457
Fuel pump shut off system ....... 458
Event data recorder .................... 459
5-2. Steps to take in an emergency If a warning light turns on or a warning buzzer
sounds... ......................................... 461
If a warning message is displayed ....................................... 470
If you have a flat tire...................... 481
If the engine will not start ......... 489
If the shift lever cannot be shifted from P ............................... 491
If you lose your keys .................... 492
If the electronic key does not operate properly ............... 493
If the vehicle battery is discharged .................................. 498
If your vehicle overheats ............ 501
If the vehicle becomes stuck............................................... 504
If your vehicle has to be stopped in an emergency ..... 506 6-1. Specifications
Maintenance data (fuel, oil level, etc.).................... 508
Fuel information ............................ 525
Tire information............................ 528
6-2. Customization Customizable features.............. 540
6-3. Initialization Items to initialize ........................... 546
Reporting safety defects for U.S. owners.......................... 548
Seat belt instructions for Canadian owners
(in French) .................................... 549
SRS airbag instructions for Canadian owners
(in French) ..................................... 551
5When trouble arises6Vehicle specifications
7For owners

IS350/250_U
9
Tires
●Rotation
● Replacement
● Inflation pressure
● Information
P. 400
P. 481
P. 519
P. 528
Tail lights P. 165
Side marker lights P. 165
Trunk P. 47
Rear window defogger *1P. 214
Doors P. 43
Fuel filler door P. 82
Turn signal lights P. 147
∗: If equipped
*1: For vehicles with a navigation system, refer to the “Navigation System Owner’s Manual”.

IS350/250_U
19
For your information
Main Owner’s Manual
Please note that this manual applies to all models and explains all equipment, includ-
ing options. Therefore, you may find some explanations for equipment not installed
on your vehicle.
All specifications provided in this manual are current at the time of printing. How-
ever, because of the Lexus policy of continual product improvement, we reserve the
right to make changes at any time without notice.
Depending on specifications, the vehicle shown in the illustration may differ from
your vehicle in terms of color and equipment.
Noise from under vehicle after turning off the engine
Approximately five hours after the engine is turned off, you may hear sound coming
from under the vehicle for several minutes. This is the sound of a fuel evaporation
leakage check and, it does not indicate a malfunction.
Accessories, spare parts and modification of your Lexus
A wide variety of non-genuine spare parts and accessories for Lexus vehicles are
currently available in the market. You should know that Toyota does not warrant
these products and is not responsible for their performance, repair, or replacement,
or for any damage they may cause to, or adverse effect they may have on, your
Lexus vehicle.
This vehicle should not be modified with non-genuine Lexus products. Modification
with non-genuine Lexus products could affect its performance, safety or durability,
and may even violate governmental regulations. In addition, damage or perfor-
mance problems resulting from the modification may not be covered under war-
ranty.

Before driving1
23
IS350/250_U
1-1. Key informationKeys ............................................... 24
1-2. Opening, closing and locking the doors and
trunk
Smart access system with push-button start ................... 28
Wireless remote control ........ 40
Doors ............................................ 43
Trunk ............................................. 47
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats .................................... 51
Driving position memory (driver’s seat) ........................... 53
Head restraints .......................... 57
Seat belts ..................................... 60
Steering wheel (manually adjustable type) ...................... 67
Steering wheel (power-adjustable type) ....... 68
Anti-glare inside rear view mirror ......................................... 70 Outside rear view mirrors...... 72
1-4. Opening and closing the windows and moon roof
Power windows .......................... 75
Moon roof ................................... 78
1-5. Refueling Opening the fuel tank cap ..... 82
1-6. Theft deterrent system Engine immobilizer system ........................................ 85
Alarm............................................ 87
Theft prevention labels (U.S.A.)...................................... 90
1-7. Safety information Correct driving posture .......... 91
SRS airbags ................................ 93
Front passenger occupant classification system............ 104
Child restraint systems ......... 109
Installing child restraints........ 113

160
2-2. Instrument cluster
IS350/250_U
Multi-information display
The multi-information display presents the driver with a variety of driving-
related data, including the current outside air temperature.
●Trip information ( →P. 1 6 1 )
Displays driving range, fuel con-
sumption and other cruising
related information.
●Satellite switch mode display
(→P. 329)
This switch is used to configure
various function settings.
●Intuitive parking assist dis-
play (if equipped) (→ P. 1 7 9 )
Automatically displayed when
using intuitive parking assist.
●Warning messages
(→P. 4 7 0 )
Automatically displayed when a
malfunction occurs in one of the
vehicle’s systems.

191
2
When driving
IS350/250_U
2-5. Driving information
Cargo and luggage
Capacity and distributionCargo capacity depends on the total weight of the occupants.
(Cargo capacity) = (Total load capacity) — (Total weight of occupants)
Steps for Determining Correct Load Limit
(1) Locate the statement “The combined weight of occupants and cargo should never exceed XXX kg or XXX lbs.” on your vehicle’s placard.
(2) Determine the combined weight of the driver and passengers that will be riding in your vehicle.
(3)Subtract the combined weight of the driver and passengers from XXX kg or XXX lbs.
(4) The resulting figure equals the available amount of cargo and luggage load capacity.
For example, if the “XXX” amount equals 1400 lbs. and there will be
five 150 lb passengers in your vehicle, the amount of available cargo
and luggage load capacity is 650 lbs. (1400 − 750 (5 × 150) = 650
lbs.)
(5)Determine the combined weight of luggage and cargo being loaded on the vehicle. That weight may not safely exceed the available cargo
and luggage load capacity calculated in Step 4.
Take notice of the following information about storage precautions, cargo
capacity and load.
●Stow cargo and luggage in the trunk whenever possible. Be sure
all items are secured in place.
● Be careful to keep the vehicle level. Placing the weight as far for-
ward as possible helps maintain vehicle balance.
● For better fuel economy, do not carry unnecessary weight.

364
3-7. Other interior features
IS350/250_U■
Stolen Vehicle Location
If your vehicle is stolen, Safety Connect can work with local authorities
to assist them in locating and recovering the vehicle. After filing a
police report, call the Safety Conne ct response center at 1-800-25-
LEXUS (1-800-255-3987) and follow the prompts for Safety Con-
nect to initiate this service.
In addition to assisting law enforcement with recovery of a stolen vehi-
cle, Safety-Connect-equipped vehicle location data may, under cer-
tain circumstances, be shared with third parties to locate your vehicle.
Further information is available at Lexus.com.
■ Emergency Assistance Button (“SOS”)
In the event of an emergency on the road, push the “SOS” button to
reach the Safety Connect response center. The answering agent will
determine your vehicle’s location, assess the emergency, and dispatch
the necessary assistance required.
If you accidentally press the “SOS” button, tell the response-center agent
that you are not experiencing an emergency.
■Enhanced Roadside Assistance
Enhanced Roadside Assistance adds GPS data to the already
included warranty-based Lexus road side service.
Subscribers can press the “SOS” button to reach a Safety Connect
response-center agent, who can help with a wide range of needs, such
as: towing, flat tire, fuel delivery, etc. For a description of the Enhanced
Roadside Assistance services and their limitations, please see the
Safety Connect Terms and Conditions, which are available at
Lexus.com.