
1, 2, 3 ...
4-ETS see ETS/4-ETS
4MATIC
see All-wheel drive (4MATIC)
A
ABS (Antilock Brake System) ............. 62
Indicator lamp ................................ 305
Messages in the multifunction
display ................................... 288, 289
Accessory weight .............................. 249
Accidents ........................................... 112
Air bags ........................................... 37
Emergency calls (Tele Aid) .............208
NECK-PRO active front head
restraints ........................................ 54
Active Bi-Xenon headlamps
see Headlamps
Adaptive Brake .................................... 64
Adaptive Highbeam Assist ............... 100
Switching on or off ......................... 142
AdBlue ®
...................................... 333, 364
Refilling ......................................... 334
Additives
Engine oil ....................................... 362
Gasoline ......................................... 364
Address change ................................... 21
Advanced Tire Pressure
Monitoring System (Advanced
TPMS) ................................................. 233
Messages in the multifunction
display ........................................... 285
Air bags ................................................ 37
Emergency call upon deployment ..208
Front, driver and passenger .............40
Front passenger front air bag off
indicator lamp (Canada
only) ........................................ 46, 313
Front passenger front air bag off
indicator lamp (USA only) ........43, 314
Knee bag .......................................... 40
Messages in the multifunction
display ........................................... 276
OCS (Occupant Classification
System) ........................................... 43
Pelvis ............................................... 42
Safety guidelines ............................. 39
Side impact ...................................... 41
Window curtain ................................ 42
Air conditioning refrigerant and
lubricant ............................................. 362
Air distribution .................................. 189
Air filter .............................................. 299
AIRMATIC
Damping system ............................ 163
Introduction ................................... 163
Messages in the multifunction
display ........................................... 292
Vehicle level control ......................163
Air pressure
see Tire inflation pressure
Air pressure (tires) ............................ 250
Air pump (electric) ............................ 327
Air recirculation mode ...................... 190
Air volume .......................................... 189
Alarm system see Anti-theft systems
Alignment bolt (vehicle tool kit) ...... 326
All-wheel drive (4MATIC) .................. 161
Alternator
Messages in the multifunction
display ................................... 284, 297
Alternator (Technical data)
see Vehicle specification
AMG adaptive sport suspension
system (E 63 AMG) ............................ 164
AMG menu ......................................... 131
Anticorrosion/antifreeze .................. 365
Antilock Brake System see ABS
Anti-theft systems ............................... 71
Anti-theft alarm system ...................72
Immobilizer ...................................... 71
Aquaplaning
see Hydroplaning
Armrest, front
Storage compartment ....................202
Armrest, rear
Storage compartment ....................202
Ashtrays ............................................. 206
Aspect ratio (tires) ............................ 250
Assistance menu ............................... 1374Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 4

RACE START (E 63 AMG) ...............159
Safety systems ................................ 61
Systems ......................................... 146
Through standing water .................257
With DISTRONIC PLUS ...................157
Driving and parking
Safety notes .................................. 109
Driving off .................................. 111, 257
Driving safety systems ....................... 61
ABS .................................................. 62
Adaptive Brake ................................ 64
BAS .................................................. 63
BAS PLUS ........................................ 63
EBP .................................................. 64
ESC .................................................. 65
ETS/4-ETS ....................................... 65
PRE-SAFE ®
Brake ............................. 69
Driving systems
AIRMATIC (except E 63 AMG) ........163
All-wheel drive (4MATIC) ................ 161
AMG adaptive sport suspension
system (E 63 AMG) ........................164
ATTENTION ASSIST ........................178
Blind Spot Assist ............................ 175
Cruise control ................................ 146
DISTRONIC PLUS ........................... 149
Hill-start assist system ..................160
HOLD function ............................... 161
Lane Keeping Assist ......................177
Night View Assist Plus ...................172
Parking Guidance ........................... 168
Parktronic system ..........................165
RACE START (E 63 AMG) ...............159
Rear view camera .......................... 171
Driving tips, automatic
transmission ...................................... 119
E
Easy-entry/exit feature .............. 93, 145
EBP (Electronic Brake
Proportioning) ...................................... 64
Electrical system
Improper work on or
modifications ................................... 22
Power outlets ................................. 207
Electrical system (Technical data)
see Vehicle specification
Electronic Stability Control
see ESC
Electronic Traction System
see ETS/4-ETS
Emergency, in case of
First aid kit ..................................... 268
Flat tire .......................................... 323
Hazard warning flasher ..................101
Roadside Assistance ................ 21, 210
Towing the vehicle .........................340
Emergency calls
Tele Aid .......................................... 208
Emergency operations
Remote door lock (Tele Aid) ........... 212
Remote door unlock (Tele Aid) .......211
Trunk lid, emergency release ...........84
Emergency Tensioning Device
see ETD
Emission control ............................... 258
Information label ............................ 347
System warranties ...........................20
Engine
Break-in recommendations ............220
Cleaning ......................................... 261
Compartment ................................ 223
Malfunction indicator lamp ............310
Messages in the multifunction
display ........................................... 295
Number .......................................... 347
Starting .......................................... 109
Turning off ..................................... 113
Engine (Technical data)
see Vehicle specification
Engine compartment
Radiator ......................................... 224
Engine coolant
see Coolant
Engine oil
Adding ........................................... 225
Additives ........................................ 362
Checking level ............................... 224
Consumption ................................. 224
Messages in the multifunction
display ........................................... 298
Oil dipstick ..................................... 225
Recommended engine oils and oil
filter ............................................... 3618Index212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 8

ESC (Electronic Stability Control) ...... 65
ETS/4-ETS ....................................... 65
Messages in the multifunction
display ........................... 288, 289, 290
Warning lamp ................................. 309
ETD (Emergency Tensioning
Device) ................................................. 52
Safety guidelines ............................. 39
ETS/4-ETS (Electronic Traction
System) ................................................ 65
Express operation
Panorama roof ............................... 195
Power windows .............................. 105
Tilt/sliding sunroof ........................192
Exterior lamp switch ........................... 97
Exterior rear view mirrors .................. 95
Parking position ............................... 95
Exterior view of vehicle ...................... 26
F
Fastening the seat belts ..................... 50
First aid kit ......................................... 268
Flat tire ............................................... 323
Lowering the vehicle ......................328
Mounting the spare wheel .............323
Preparing the vehicle .....................323
Spare wheel ........................... 323, 358
TIREFIT (tire repair kit) ...................329
Floormats ........................................... 217
Fluids
Automatic transmission fluid .........360
Brake fluid ..................................... 361
Capacities ...................................... 359
Engine coolant ............................... 361
Engine oil ....................................... 360
Power steering fluid .......................360
Washer and headlamp cleaning
system ........................................... 361
Fog lamps ............................................. 99
Messages in the multifunction
display ................................... 300, 302
Four-wheel drive
see All-wheel drive (4MATIC)
Front air bags
see Air bags
Front axle oil ...................................... 360
Front lamps
see Headlamps
Front passenger front air bag ............ 40
Messages in the multifunction
display ........................................... 276
Front passenger front air bag off
indicator lamp (Canada only) ..... 46, 313
Front passenger front air bag off
indicator lamp (USA only) .......... 43, 314
Fuel ..................................................... 220
Additives ........................................ 364
Capacity, fuel tank .........................361
Diesel fuel ...................................... 363
Drive sensibly–safe fuel .................254
Fuel consumption statistics ...........130
Fuel filler flap and cap ...................222
Fuel tank reserve warning lamp .....310
Premium unleaded gasoline ...........362
Refueling ........................................ 220
Requirements ................................ 363
Fuel filler flap ..................................... 222
Opening manually ..........................316
Fuel gauge ......................................... 126
Fuels, coolants, lubricants etc. ........ 359
Fuel system, bleeding (diesel
engine) ............................................... 333
Fuel tank
Capacity ........................................ 361
Fuel filler flap and cap ...................222
Refueling ........................................ 220
Fuses .................................................. 343
G
Garage door opener .................... 33, 212
Gasoline see Fuel
GAWR (Gross Axle Weight Rating) ... 250
Gear range ......................................... 120
Indicator ........................................ 120
Limiting .......................................... 122
Shifting into optimal ......................122
Gear selector lever ............................ 115
Cleaning ......................................... 265
Gearshift pattern ........................... 115
Shifting procedure .........................118
Transmission position indicator .....118
Transmission positions ..................118
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T
Tachometer .................................. 28, 126
Overspeed range ........................... 126
Tail lamps
Cleaning lenses ............................. 262
Tar stains ........................................... 261
Technical data
Air conditioning refrigerant ............362
Brake fluid ..................................... 362
Capacities fuels, coolants,
lubricants etc. ................................ 359
Coolant .......................................... 365
Engine oil additives ........................362
Engine oils ..................................... 361
Fuel requirements .......................... 363
Gasoline additives .......................... 364
Identification labels .......................346
Premium unleaded gasoline ...........362
Rims and tires ................................ 353
Spare wheel ................................... 358
Vehicle specification E 350 ............ 348
Vehicle specification
E 350 4MATIC ................................ 349
Vehicle specification
E 350 BlueTEC ............................... 348
Vehicle specification E 550 ............ 350
Vehicle specification
E 550 4MATIC ................................ 351
Vehicle specification E 63 AMG .....352
Washer and headlamp cleaning
system ................................... 361, 367
Technical data (dimensions)
see Vehicle specification
Technical data (electrical system)
see Vehicle specification
Technical data (engine)
see Vehicle specification
Technical data (weights)
see Vehicle specification
Tele Aid ............................................... 207
Emergency calls ............................. 208
Information button .........................210
Initiating an emergency call
manually ........................................ 209
Messages in the multifunction
display ........................................... 290
Remote door lock .......................... 212Remote door unlock ......................211
Roadside Assistance button ..........210
Search & Send ............................... 211
SOS button .................................... 209
Stolen Vehicle Recovery Services ..212
System self-test ............................. 208
Telephone ............................................. 30
Answering/ending a call ................136
Hands-free microphone ...................33
Menu ............................................. 135
Operation ....................................... 135
Phone book .................................... 136
Redialing ........................................ 137
Temperature
Coolant .......................................... 125
Interior temperature ......................186
Outside .......................................... 126
Tether anchorage points
see Children in the vehicle
Through-loading feature ................... 198
Tie-down rings ................................... 199
Tightening torque
Wheels ........................................... 328
TIN (Tire Identification Number) ...... 251
Tire and Loading Information
placard ............................................... 237
Tire and loading terminology ........... 249
TIREFIT ............................................... 329
Tire Identification Number see TIN
Tire inflation pressure
Checking ........................................ 231
Important notes on ........................230
Label on the inside of fuel filler
flap ................................................ 230
Placard on driver’s door B-pillar .....237
Tire labeling ....................................... 245
Tire load rating .................................. 250
Tire ply composition and material
used .................................................... 251
Tire pressure loss warning system . 232
Tire repair kit see TIREFIT
Tires ........................................... 228, 353
Advanced Tire Pressure
Monitoring System (Advanced
TPMS) ............................................ 233Index17212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 17

V
Valet locking ........................................ 85
Vehicle
Battery ........................................... 336
Care ............................................... 260
Control system .............................. 126
Identification Number (VIN) ...........346
Locking/unlocking ........................... 76
Lowering (wheel change) ...............328
Modifications and alterations,
Operating safety .............................. 22
Towing ........................................... 340
Unlocking/locking manually ..........314
Vehicle dimensions
see Vehicle specification
Vehicle Identification Number
(VIN) ................................................... 346
Vehicle jack see Jack
Vehicle level control
see AIRMATIC
Vehicle lighting .................................... 97
Vehicle loading
Cargo tie-down rings ...................... 199
Instructions .................................... 197
Load limit ....................................... 238
Roof rack ....................................... 198
Split rear seat bench .....................199
Terminology ................................... 249
Vehicle maximum load on the tire ... 252
Vehicle specification
E 350 ............................................. 348
E 350 4MATIC ................................ 349
E 350 BlueTEC ............................... 348
E 550 ............................................. 350
E 550 4MATIC ................................ 351
E 63 AMG ...................................... 352
Vehicle status message memory .... 139
Vehicle tool kit .................................. 268
Vehicle washing see Vehicle care
Vehicle weights
see Vehicle specification W
Warning sounds
DISTRONIC PLUS ........................... 151
Driver’s or passenger’s seat belt .....52
Parking brake ................................ 289
Parking Guidance ........................... 170
Parktronic system ..........................168
Seat belt telltale ............................ 307
Warranty coverage ............................ 346
Washer and headlamp cleaning
system ................................................ 367
Washer fluid
Messages in the multifunction
display ........................................... 294
Mixing ratio .................................... 367
Refilling .......................................... 227
Washing the vehicle .......................... 260
Wear pattern (tires) .......................... 244
Weights (vehicle) see Vehicle specification
Wheel
Changing ....................................... 323
Removing ....................................... 326
Spare ............................................. 323
Tightening torque ........................... 328
Wheels, sizes ..................................... 353
Wheels, Tires and .............................. 228
Window curtain air bags ..................... 42
Windows see Power windows
Windows, cleaning ............................ 264
Windshield
Cleaning wiper blades .................... 264
Washer fluid ................................... 367
Wipers ........................................... 104
Windshield wipers
Replacing wiper blades ..................322
Winter cover .............................. 224, 252
Winter driving
Instructions .................................... 253
Radiator cover ............................... 252
Snow chains .................................. 252
Tires ............................................... 252
Winter tires ................................ 252, 353
Wood trims, cleaning ........................ 266Index19212_AKB; 2; 41, en-USd2ureepe,Version: 2.11.8.12009-07-17T09:14:21+02:00 - Seite 19

ESCGObserve Safety notes, see page 62.
The Electronic Stability Control (ESC) is
operational as soon as the engine is running.
It monitors the vehicle’s traction (force of
adhesive friction between the tires and the
road surface) and handling.
The ESC recognizes that the vehicle deviates
from the direction of travel as intended by the
driver. By applying brakes to individual
wheels and by limiting the engine output, the
ESC works to stabilize the vehicle. The ESC is
especially useful while driving off and on wet
or slippery road surfaces. The ESC also
stabilizes the vehicle during braking and
steering maneuvers.
The ESC warning lamp ä in the instrument
cluster comes on when you switch on the
ignition. It goes out when the engine is
running.
GWarning!
Never switch off the ESC when you see the
ESC warning lamp ä flashing in the
instrument cluster. In this case proceed as
follows:
R When driving off, apply as little throttle as
possible.
R While driving, ease up on the accelerator
pedal.
R Adapt your speed and driving style to the
prevailing road conditions.
Failure to observe these guidelines could
cause the vehicle to skid. The ESC cannot
prevent accidents resulting from excessive
speed.
! Vehicles with 4MATIC: Because the ESC
operates automatically, the engine and
ignition must be shut off (SmartKey in
starter switch position 0 or 1 or KEYLESS-
GO start/stop button in position 0 or 1)
when the parking brake is being tested on
a brake test dynamometer.
Active braking action through the ESC may
otherwise seriously damage the brake
system which is not covered by the
Mercedes-Benz Limited Warranty.
! Vehicles without 4MATIC: Because the
ESC operates automatically, the engine
and ignition must be shut off (SmartKey in
starter switch position 0 or 1 or KEYLESS-
GO start/stop button in position 0 or 1)
when the parking brake is being tested on
a brake test dynamometer or when the
vehicle is being towed with one axle raised.
Active braking action through the ESC may
otherwise seriously damage the brake
system which is not covered by the
Mercedes-Benz Limited Warranty.
! The ESC will only function properly if you
use wheels of the recommended tire size
as specified in the “Technical data” section
of this Operator’s Manual.
i The DISTRONIC PLUS and cruise control
switch off automatically when the ESC
engages.
Electronic Traction System
(ETS/4-ETS) GObserve Safety notes, see page 62.
The ETS (Electronic Traction System) and
4-ETS (four-wheel Electronic Traction
System, vehicles with 4MATIC only) are
components of the ESC. The ETS/4-ETS
improves the vehicle’s ability to utilize
available traction, especially under slippery
road conditions by applying the brakes to a
spinning wheel. Vehicles with 4MATIC also
transfer more power to the wheel(s) with
traction.
When you switch off the ESC, the
ETS/4-ETS is still enabled.
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DownshiftingGWarning!
On slippery road surfaces, never downshift in
order to obtain braking action. This could
result in drive wheel slip and reduced vehicle
control. Your vehicle’s ABS will not prevent
this type of loss of control.
XBriefly pull left gearshift control :
( Y page 122).
The automatic transmission shifts into the
next lower gear.
i When you brake or stop, the automatic
transmission shifts down into a gear from
which you can easily accelerate or take off.
Kickdown
Using the kickdown while driving in manual
program mode M is not possible.
Deactivating manual shift program
XTurn the program mode selector dial until
C or S appears in the multifunction display.
or
XRestart the engine.
The automatic transmission will go to
automatic program mode C.
Manual program mode M is not stored.
Emergency operation (limp-home
mode)
If vehicle acceleration becomes less
responsive or sluggish or the automatic
transmission no longer shifts, the automatic
transmission is most likely operating in limp-
home (emergency operation) mode. In this
mode only second gear and reverse gear R
can be selected.
XStop the vehicle in a safe location.XShift the automatic transmission into park
position P.XTurn off the engine.XWait at least 10 seconds before restarting.XRestart the engine.XShift the automatic transmission into drive
position D (for second gear) or reverse gear
R .XHave the automatic transmission checked
at an authorized Mercedes-Benz Center as
soon as possible.
Transfer case
This section applies to vehicles equipped with
all-wheel drive (4MATIC) only. Both the front
and rear axles are powered at all times when
the vehicle is being operated.
! Only conduct operational or performance
tests on a two-axle dynamometer. If such
tests are necessary, contact an authorized
Mercedes-Benz Center. You could
otherwise seriously damage the brake
system or the transfer case which is not
covered by the Mercedes-Benz Limited
Warranty.
! Because the ESC operates automatically,
the engine and ignition must be shut off
(SmartKey in starter switch position 0, or
1 , or KEYLESS-GO start/stop button in
position 0, or 1) when
R the parking brake is being tested on a
brake test dynamometer
R towing the vehicle with the front or rear
axle raised (not permissible for vehicles
with 4MATIC)
Active braking action through the ESC may
otherwise seriously damage the brake
system which is not covered by the
Mercedes-Benz Limited Warranty.
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XPress button = or ; to select the
Sett. menu.
XPress button : or 9 to select the
Convenience submenu.
XPress a.XPress button : or 9 to select the
Belt Adjustment: function.
The current setting Enabled or Disabled
is shown.
XPress button a to change the current
status.
Depending on the previous status, the
Belt Adjustment: function will be
Enabled or Disabled.
Driving systems
Introduction
RCruise control
RDISTRONIC PLUS
RHill-start assist system
RHOLD function
RAIRMATIC (E 550 and E 550 4MATIC)
RAll-wheel drive (4MATIC)
RParktronic system with Parking Guidance
RRear view camera
RNight View Assist Plus
RATTENTION ASSIST
RBlind Spot Assist
RLane Keeping Assist
RRACE START (E 63 AMG)
RAMG adaptive sport suspension system
(E 63 AMG)
The driving safety systems ABS, Adaptive
Brake, BAS, BAS PLUS, EBP, ESC and PRE-
SAFE® Brake are described in the “Safety and
security” section (Y page 61).
Cruise control
The cruise control maintains the speed you
set for your vehicle automatically.
The use of the cruise control is recommended
for driving at a constant speed for extended
periods of time.
The currently set speed or last set speed
(“Resume” function) appears in the
multifunction display for approximately
5 seconds. The corresponding cruise control
speed segments from the selected speed to
the vehicle maximum speed in the
multifunction display are illuminated.
GWarning!
The cruise control is a convenience system
designed to assist the driver during vehicle
operation. The driver is and must always
remain responsible for the vehicle’s speed
and for safe brake operation.
Only use the cruise control if the road, traffic,
and weather conditions make it advisable to
travel at a constant speed.
RThe use of the cruise control can be
dangerous on winding roads or in heavy
traffic because conditions do not allow safe
driving at a constant speed.
RThe use of the cruise control can be
dangerous on slippery roads. Rapid
changes in tire traction can result in wheel
spin and loss of control.
RDeactivate the cruise control when driving
in fog.
The “Resume” function should only be
operated if the driver is fully aware of the
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