Page 15 of 586
10_IS250C/350C_U
14
Pictorial indexInstrument panel
Headlight switch Turn signal lever
Fog light switch P. 173
P. 156
P. 176
Shift paddle switches (automatic transmission) P. 151
Gauges and meters P. 159
Multi-information display P. 168
Windshield wiper and washer switch P. 177
Engine (ignition) switch P. 142
Trunk opener main switch P. 47
Tilt and telescopic steering control switch P. 72
Audio remote control switches *2P. 286
Horn P. 158Glove box P. 340
Parking brake pedal (automatic transmission) P. 157
Hood lock release lever P. 389
Inside door lock buttons P. 43
Page 27 of 586

26
1-1. Key information
10_IS250C/350C_U
●The card key is not waterproof.
■When required to leave a key to the vehicle with a parking attendant
Turn the trunk opener main switch off and lock the glove box as circumstances
demand. (→P. 4 7 , 3 4 0 )
Remove the mechanical key for your own use and provide the attendant with the
electronic key only.
■Key number plate
Keep the plate in a safe place such as your wallet, not in the vehicle. In the event that
a mechanical key is lost, a new key can be made at your Lexus dealer using the key
number plate. ( →P. 500)
■When riding in an aircraft
When bringing an electronic key onto an aircraft, make sure you do not press any
buttons on the electronic key while inside the aircraft cabin. If you are carrying an
electronic key in your bag etc, ensure that the buttons are not likely to be pressed
accidentally. Pressing a button may cause the electronic key to emit radio waves
that could interfere with the operation of the aircraft.
●If the battery cover is not installed and
the battery falls out or if the battery was
removed because the key got wet, rein-
stall the battery with the positive termi-
nal facing the Lexus emblem.
Page 34 of 586

33
1-2. Opening, closing and locking the doors and trunk
1
Before driving
10_IS250C/350C_U
■Switching the door unlock function
It is possible to set which doors the entry function unlocks. Turn the “ENGINE START STOP” switch OFF.
When the indicator on the key surface is turned off, push and
hold , or for approximately 5 seconds while pushingon the key.
The setting changes each time an operation is performed, as shown below. (When
changing the setting continuously, release the buttons, wait for at least 5 seconds,
and repeat step 2.)
Unlock the doors using the electronic key and open one of the doors.
If a door is not opened within 60 seconds after is pressed, the doors
will be locked again and the alarm will automatically be set. In case that
the alarm is triggered, immediately stop the alarm. ( →P. 9 5 )
STEP1
STEP2
Multi-information
displayUnlocking doorsBeep
Hold the driver's door handle
to unlock only the driver's
door.
Exterior: Beeps three
times
Interior: Pings once
Hold the passenger’s door
handle to unlock both side
doors.
Hold either door handle to
unlock both side doors.Exterior: Beeps twice
Interior: Pings once
STEP3
Page 44 of 586
43
1
1-2. Opening, closing and locking the doors and trunk
Before driving
10_IS250C/350C_U
Doors
The vehicle can be locked and unlocked using the entry function, wireless
remote control or door lock switch.
■Entry function
→ P. 2 9
■ Wireless remote control
→ P. 4 0
■ Door lock switch
Locks both side doors
Unlocks both side doors
■ Inside lock button
Locks the door
Unlocks the door
The both side doors can be
opened by pulling the inside
handle even if the lock buttons
are in the lock position.
Page 47 of 586

46
1-2. Opening, closing and locking the doors and trunk
10_IS250C/350C_U
■Side window open/close function linked to door operation
When a door is opened, its window opens slightly. When a door is closed, its win-
dow closes completely.
■Impact detection door lock release system
In the event that the vehicle is subject to a strong impact, both side doors are
unlocked. Depending on the force of the impact or the type of accident, however,
the system may not operate.
■Using the mechanical key
The doors can also be locked and unlocked with the mechanical key. (→P. 5 0 1 )
■Customization that can be configured at Lexus dealer
Settings (e.g. unlocking function using a key) can be changed.
(Customizable features →P. 5 5 7 )
CAUTION
■To prevent an accident
Observe the following precautions while driving the vehicle.
Failing to do so may result in a door opening and an occupant falling out, resulting in
death or serious injury.
●Always use a seat belt.
●Always lock both side doors.
●Ensure that both side doors are properly closed.
●Do not pull the inside handle of the doors while driving.
The doors may be opened and the passengers are thrown out of the vehicle and it
may result in serious injury or death.
Both side doors may be opened even if the inside lock buttons are in locked posi-
tion.
Page 121 of 586
120
1-7. Safety information
10_IS250C/350C_U
Installing child restraints
Follow the child restraint system manufacturer's instructions. Firmly
secure child restraints to the rear seats using the LATCH anchors or a seat
belt. Attach the top tether strap when installing a child restraint.
The lap/shoulder belt can be used if your child restraint system is not com-
patible with the LATCH (Lower Anchor s and Tethers for Children) system.
Child restraint LATCH anchors
LATCH anchors are provided
for each rear seat. (Buttons dis-
playing the location of the
anchors are attached to the
seats.)
Seat belts equipped with a child
restraint locking mechanism
(ALR/ELR belts except driver’s
seat belt) (→P. 6 5 )
Anchor bracket (for top tether
strap)
Anchor brackets are provided
for both rear seats.
Page 243 of 586
242
3-2. Using the audio system
10_IS250C/350C_U
Using the radio
Ty p e A
Ty p e B
Seeking any traffic
program stationStation
selector Displays radio text messages
Po w e r Vo l u m e
Scans for receivable stations
Seeking the
frequency
Changing the program typesAdjusting the frequency
(AM, FM mode) or
channel (SAT mode)
AM ⋅FM/SAT
mode buttons
Silencing a sound
Scans for receivable
stations Station
selector Silencing a sound
Po w e r Vo l u m e
Seeking the
frequency Station selectorAdjusting the frequency
AM/FM
mode buttons
Page 363 of 586
362
3-7. Other interior features
10_IS250C/350C_U
Garage door opener
The garage door opener (HomeLink Universal Transceiver) is manufactured
under license from HomeLink.
Programming the HomeLink (for U.S.A. owners)
The HomeLink
compatible transceiver in your vehicle has 3 buttons
which can be programmed to operate 3 different devices. Refer to the
programming method below appropriate for the device.
Indicator
Buttons
■ Programming the HomeLink
Point the remote control transmit-
ter for the device 1 to 3 in. (25 to
75 mm) from the HomeLink
but-
tons.
Keep the HomeLink indicator
light in view while programming.
The garage door opener can be pr ogrammed to operate garage doors,
gates, entry doors, door locks, home lighting systems, and security systems,
and other devices.
STEP1