Page 3 of 586

TABLE OF CONTENTSIndex
10_IS250C/350C_U
2
1-1. Key informationKeys ...................................................... 24
1-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start .......................... 28
Wireless remote control .............. 40
Doors.................................................... 43
Trunk..................................................... 47
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats ........................................... 51
Driving position memory (driver’s seat) ................................. 56
Seat position memory (front passenger’s seat) ............. 60
Head restraints................................. 62
Seat belts ............................................ 65
Steering wheel.................................. 72
Anti-glare inside rear view mirror...................................... 74
Outside rear view mirrors ........... 75 1-4. Opening and closing the
windows and retractable
hardtop
Power windows................................ 78
Retractable hardtop........................ 81
1-5. Refueling Opening the fuel tank cap........... 90
1-6. Theft deterrent system Engine immobilizer system ......... 93
Alarm.................................................... 95
Theft prevention labels (U.S.A.) ............................................. 97
1-7. Safety information Correct driving posture ............... 98
SRS airbags ..................................... 100
Front passenger occupant classification system ..................... 111
Child restraint systems ................. 116
Installing child restraints ............. 120
1Before driving
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1
2
3
4
5
6
7
10_IS250C/350C_U
3
2-1. Driving proceduresDriving the vehicle ........................ 132
Engine (ignition) switch .............. 142
Automatic transmission.............. 147
Manual transmission .................... 154
Turn signal lever ............................ 156
Parking brake ................................. 157
Horn.................................................... 158
2-2. Instrument cluster Gauges and meters ..................... 159
Indicators and warning lights ... 165
Multi-information display........... 168
2-3. Operating the lights and windshield wipers
Headlight switch ............................ 173
Fog light switch .............................. 176
Windshield wipers and washer.............................................. 177
Headlight cleaner switch ........... 182 2-4. Using other driving systems
Cruise control ................................ 183
Dynamic radar cruise control............................................. 187
Intuitive parking assist ................. 198
Driving assist systems................. 204
Hill-start assist control ................ 210
PCS (Pre-Collision System)..... 212
2-5. Driving information Cargo and luggage ...................... 216
Vehicle load limits......................... 219
Winter driving tips ....................... 220
Trailer towing ................................. 224
Dinghy towing (vehicles with an
automatic transmission) ......... 225
Dinghy towing (vehicles with a
manual transmission)............... 226
2When driving
Page 7 of 586

TABLE OF CONTENTSIndex
10_IS250C/350C_U
6
5-1. Essential informationEmergency flashers..................... 452
If your vehicle needs to be towed ....................................... 453
If you think something is wrong ............................................. 459
Fuel pump shut off system ....... 460
Event data recorder ..................... 461
5-2. Steps to take in an emergency If a warning light turns on or a warning buzzer
sounds... ........................................ 463
If a warning message is displayed ....................................... 472
If you have a flat tire (vehicles with standard
tires) ............................................... 486
If you have a flat tire (vehicles with run-flat
tires) ................................................ 495
If the engine will not start .......... 497
If the shift lever cannot be shifted from P........................ 499
If you lose your keys ................... 500
If the electronic key does not operate properly ................ 501
If the vehicle battery is discharged .................................. 506
If your vehicle overheats .......... 509 If the vehicle becomes stuck .... 512
If the retractable hardtop
does not close.............................. 514
6-1. Specifications Maintenance data (fuel, oil level, etc.)..................... 526
Fuel information ............................ 542
Tire information............................. 545
6-2. Customization Customizable features............... 557
6-3. Initialization Items to initialize ........................... 562
Reporting safety defects for U.S. owners........................... 564
Seat belt instructions for Canadian owners
(in French) ................................... 565
5When trouble arises
6Vehicle specifications
7For owners
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10_IS250C/350C_U
21
CAUTION
■General precautions while driving
Driving under the influence: Never drive your vehicle when under the influence of
alcohol or drugs that have impaired your ability to operate your vehicle. Alcohol
and certain drugs delay reaction time, impair judgment and reduce coordination,
which could lead to an accident that could result in death or serious injury.
Defensive driving: Always drive defensively. Anticipate mistakes that other drivers
or pedestrians might make and be ready to avoid accidents.
Driver distraction: Always give your full attention to driving. Anything that distracts
the driver, such as adjusting controls, talking on a cellular phone or reading can
result in a collision with resulting death or serious injury to you, your occupants or
others.
■General precaution regarding children’s safety
Never leave children unattended in the vehicle, and never allow children to have or
use the key.
Children may be able to start the vehicle or shift the vehicle into neutral. There is
also a danger that children may injure themselves by playing with the cigarette
lighter, the windows, the retractable hardtop, or other features of the vehicle. In
addition, heat build-up or extremely cold temperatures inside the vehicle can be
fatal to children.
Page 24 of 586

Before driving1
23
10_IS250C/350C_U
1-1. Key informationKeys ............................................... 24
1-2. Opening, closing and locking the doors and
trunk
Smart access system with push-button start ................... 28
Wireless remote control ........ 40
Doors ............................................ 43
Trunk ............................................. 47
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats .................................... 51
Driving position memory (driver’s seat) ........................... 56
Seat position memory (front passenger’s seat) ........ 60
Head restraints .......................... 62
Seat belts ..................................... 65
Steering wheel........................... 72
Anti-glare inside rear view mirror ............................... 74
Outside rear view mirrors ...... 75 1-4. Opening and closing the
windows and retractable
hardtop
Power windows .......................... 78
Retractable hardtop ................. 81
1-5. Refueling Opening the fuel tank cap ..... 90
1-6. Theft deterrent system Engine immobilizer system.... 93
Alarm............................................ 95
Theft prevention labels (U.S.A.)...................................... 97
1-7. Safety information Correct driving posture ......... 98
SRS airbags .............................. 100
Front passenger occupant classification system............... 111
Child restraint systems ........... 116
Installing child restraints....... 120
Page 25 of 586
24
10_IS250C/350C_U
1-1. Key information
Keys
The following keys are provided with the vehicle.
Electronic keys
• Operating the smart accesssystem with push-button start
(→ P. 2 8 )
• Operating the wireless remote control function
(→ P. 4 0 )
Mechanical keys
Key number plate
■ Card key (if equipped)
Electronic key
Operating the smart access sys-
tem with push-button start
(→ P. 2 8 )
Mechanical key
The card key comes with an information card that includes instructions
for use. Lexus recommends that you carry the information card with
the card key.
Page 29 of 586
28
10_IS250C/350C_U
1-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start
The following operations can be performed simply by carrying the elec-
tronic key (including the card key∗) on your person, for example in your
pocket.
(The driver should always carry the electronic key.)
Locks and unlocks the doors ( →P. 2 9 )
Unlocks the trunk ( →P. 2 9 )
Starts the engine ( →P. 142)
∗
: If equipped
Page 32 of 586
31
1-2. Opening, closing and locking the doors and trunk
1
Before driving
10_IS250C/350C_U■
Effective range (areas within wh ich the electronic key is detected)
When locking or unlocking
the doors
The system can be operated
when the electronic key is out-
side the vehicle, within about
2.3 ft. (70 cm) of either of the
outside door handles. (Only
the doors detecting the key
can be operated.)
When unlocking the trunk
The system can be operated
when the electronic key is
within about 2.3 ft. (70 cm) of
the trunk release button.
When starting the engine
or changing “ENGINE
START STOP” switch
modes
The system can be operated
when the electronic key is
inside the vehicle.