Page 4 of 543

TABLE OF CONTENTSIndex
ES350_U
2
1-1. Key informationKeys ...................................................... 24
1-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start .......................... 26
Wireless remote control ............. 38
Doors..................................................... 41
Trunk..................................................... 45
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats .......................................... 49
Driving position memory (driver’s seat) ................................ 50
Seat position memory (front passenger’s seat) ............. 54
Head restraints................................. 56
Seat belts ........................................... 58
Steering wheel.................................. 64
Anti-glare inside rear view mirror ................................................ 65
Outside rear view mirrors ........... 66
1-4. Opening and closing the windows and moon roof
Power windows................................ 68
Moon roof ............................................ 71 1-5. Refueling
Opening the fuel tank cap........... 75
1-6. Theft deterrent system Engine immobilizer system ......... 78
Alarm................................................... 80
Theft prevention labels (for USA) ......................................... 82
1-7. Safety information Correct driving posture ............... 83
SRS airbags ...................................... 85
Front passenger occupant classification system .................... 96
Child restraint systems ................ 101
Installing child restraints ............. 105
2-1. Driving procedures Driving the vehicle .......................... 116
Engine (ignition) switch .............. 124
Automatic Transmission ............ 128
Turn signal lever............................... 131
Parking brake ................................. 132
Horn.................................................... 133
1Before driving
2When driving
Page 7 of 543

1
2
3
4
5
6
7
ES350_U
5
4-1. Maintenance and careCleaning and protecting the vehicle exterior................... 354
Cleaning and protecting the vehicle interior .................... 357
4-2. Maintenance Maintenance requirements .... 360
General maintenance ................ 362
Emission inspection and maintenance (I/M)
programs ...................................... 365
4-3. Do-it-yourself maintenance Do-it-yourself service precautions .................................. 366
Hood.................................................. 370
Positioning a floor jack................ 371
Engine compartment.................. 373
Tires ................................................... 387
Tire inflation pressure................. 396
Wheels............................................. 400
Air conditioning filter.................. 402
Electronic key battery ................ 404
Checking and replacing fuses ................................................ 406
Headlight aim ................................. 415
Light bulbs ........................................ 417 5-1. Essential information
Emergency flashers .................... 428
If your vehicle needs to be towed ....................................... 429
If you think something is wrong ......................................... 435
Fuel pump shut off system ........ 436
Event data recorder.................... 437
5-2. Steps to take in an emergency If a warning light turns on or a warning buzzer
sounds... ........................................ 439
If a warning message is displayed....................................... 449
If you have a flat tire...................... 461
If the engine will not start ............ 471
If the shift lever cannot be shifted from P .............................. 473
If you lose your keys .................... 474
If the electronic key does not operate properly ............... 475
If the vehicle battery is discharged ................................... 477
If your vehicle overheats .......... 480
If the vehicle becomes stuck............................................... 483
4Maintenance and care5When trouble arises
Page 8 of 543
TABLE OF CONTENTSIndex
ES350_U
6
6-1. SpecificationsMaintenance data (fuel, oil level, etc.).................... 486
Fuel information ............................ 496
Tire information............................. 499
6-2. Customization Customizable features.................. 511
6-3. Initialization Items to initialize ............................ 519
Reporting safety defects for U.S. owners........................... 522
Seat belt instructions for Canadian owners
(in French) .................................... 523
Abbreviation list................................... 526
Alphabetical index .............................. 528
What to do if... ...................................... 538
6Vehicle specifications
7For owners
Index
Page 11 of 543
ES350_U
9
Tires
●Rotation
● Replacement
● Inflation pressure
P. 387
P. 461
P. 493
Tail lights P. 145
Side marker lights P. 145
Trunk P. 45
Rear window defogger P. 207
Doors P. 41
Fuel filler door P. 75
Turn signal lights P. 131
Page 19 of 543
ES350_U
17
C
Rear sunshade
switch
∗ P. 329
Intuitive parking assist
switch
∗ * P. 165
Instrument panel light
control
P. 135
∗: If equipped
*: Refer to “Navigation System Owner's Manual”.
Outside rear view mirror switch P. 66
Auxiliary box P. 317
Type A
Type B
Trunk opener P. 45
Fuel filler door opener P. 75
Rear sunshade
switch
∗ P. 329
Instrument panel light
control
P. 135
Outside rear view mirror switch P. 66
Auxiliary box P. 317
Trunk opener P. 45
Fuel filler door opener P. 75
VSC off switch P. 172
VSC off switch P. 172
Page 20 of 543
ES350_U
18
For your information
Main Owner’s Manual
Please note that this manual applies to all models and explains all equipment, includ-
ing options. Therefore, you may find some explanations for equipment not installed
on your vehicle.
All specifications provided in this manual are current at the time of printing. How-
ever, because of the Lexus policy of continual product improvement, we reserve the
right to make changes at any time without notice.
Depending on specifications, the vehicle shown in the illustration may differ from
your vehicle in terms of color and equipment.
Noise from under vehicle after turning off the engine
Approximately five hours after the engine is turned off, you may hear sound coming
from under the vehicle for several minutes. This is the sound of a fuel evaporation
leakage check and, it does not indicate a malfunction.
Page 21 of 543

ES350_U
19
Accessories, spare parts and modification of your Lexus
A wide variety of non-genuine spare parts and accessories for Lexus vehicles are
currently available in the market. You should know that Toyota does not warrant
these products and is not responsible for their performance, repair, or replacement,
or for any damage they may cause to, or adverse effect they may have on, your
Lexus vehicle.
This vehicle should not be modified with non-genuine Lexus products. Modification
with non-genuine Lexus products could affect its performance, safety or durability,
and may even violate governmental regulations. In addition, damage or perfor-
mance problems resulting from the modification may not be covered under war-
ranty.
Installation of a mobile two-way radio system
As the installation of a mobile two-way radio system in your vehicle could affect
electronic systems such as the multiport fuel injection system/sequential multiport
fuel injection system, cruise control system, anti-lock brake system, SRS airbag sys-
tem and seat belt pretensioner system, be sure to check with your Lexus dealer for
precautionary measures or special instructions regarding installation.
Page 25 of 543

Before driving1
23
ES350_U
1-1. Key informationKeys ............................................... 24
1-2. Opening, closing and locking the doors and
trunk
Smart access system with push-button start .................... 26
Wireless remote control ........ 38
Doors ............................................. 41
Trunk ............................................. 45
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats ................................... 49
Driving position memory (driver’s seat) .......................... 50
Seat position memory (front passenger’s seat) ........ 54
Head restraints .......................... 56
Seat belts .................................... 58
Steering wheel........................... 64
Anti-glare inside rear view mirror ......................................... 65
Outside rear view mirrors ...... 66 1-4. Opening and closing the
windows and moon roof
Power windows .......................... 68
Moon roof .................................... 71
1-5. Refueling Opening the fuel tank cap ..... 75
1-6. Theft deterrent system Engine immobilizer system.... 78
Alarm............................................ 80
Theft prevention labels (for USA) .................................. 82
1-7. Safety information Correct driving posture ......... 83
SRS airbags ................................ 85
Front passenger occupant classification system.............. 96
Child restraint systems .......... 101
Installing child restraints....... 105