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TABLE OF CONTENTSIndex
ES350_U
2
1-1. Key informationKeys ...................................................... 24
1-2. Opening, closing and locking the doors and trunk
Smart access system with push-button start .......................... 26
Wireless remote control ............. 38
Doors..................................................... 41
Trunk..................................................... 45
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats .......................................... 49
Driving position memory (driver’s seat) ................................ 50
Seat position memory (front passenger’s seat) ............. 54
Head restraints................................. 56
Seat belts ........................................... 58
Steering wheel.................................. 64
Anti-glare inside rear view mirror ................................................ 65
Outside rear view mirrors ........... 66
1-4. Opening and closing the windows and moon roof
Power windows................................ 68
Moon roof ............................................ 71 1-5. Refueling
Opening the fuel tank cap........... 75
1-6. Theft deterrent system Engine immobilizer system ......... 78
Alarm................................................... 80
Theft prevention labels (for USA) ......................................... 82
1-7. Safety information Correct driving posture ............... 83
SRS airbags ...................................... 85
Front passenger occupant classification system .................... 96
Child restraint systems ................ 101
Installing child restraints ............. 105
2-1. Driving procedures Driving the vehicle .......................... 116
Engine (ignition) switch .............. 124
Automatic Transmission ............ 128
Turn signal lever............................... 131
Parking brake ................................. 132
Horn.................................................... 133
1Before driving
2When driving
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ES350_U
10
A
Pictorial indexInterior
Power window switches P. 68
SRS front passenger airbag P. 85
SRS knee airbags P. 85
SRS driver airbag P. 85
Floor mat P. 333
Console box P. 313
Seat belts P. 58
Front seats P. 49
SRS side airbags P. 85
Power outlet P. 323
AUX adapter P. 252
USB adapter∗ P. 233, 241
Cup holders P. 315
Armrest P. 328
Head restraints P. 56
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ES350_U
11
ACompass P. 342
Anti-glare inside rear view mirror P. 65
Moon roof switches P. 71
Personal/interior lights P. 310
Vanity mirrors P. 319
Sun visors P. 318
Personal lights P. 310
SRS curtain shieldairbags
P. 85
Overhead console P. 314
Coat hooks P. 332
Garage door opener switches P. 336
“SOS” button∗ P. 346
∗: If equipped
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ES350_U
19
Accessories, spare parts and modification of your Lexus
A wide variety of non-genuine spare parts and accessories for Lexus vehicles are
currently available in the market. You should know that Toyota does not warrant
these products and is not responsible for their performance, repair, or replacement,
or for any damage they may cause to, or adverse effect they may have on, your
Lexus vehicle.
This vehicle should not be modified with non-genuine Lexus products. Modification
with non-genuine Lexus products could affect its performance, safety or durability,
and may even violate governmental regulations. In addition, damage or perfor-
mance problems resulting from the modification may not be covered under war-
ranty.
Installation of a mobile two-way radio system
As the installation of a mobile two-way radio system in your vehicle could affect
electronic systems such as the multiport fuel injection system/sequential multiport
fuel injection system, cruise control system, anti-lock brake system, SRS airbag sys-
tem and seat belt pretensioner system, be sure to check with your Lexus dealer for
precautionary measures or special instructions regarding installation.
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ES350_U
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Scrapping of your Lexus
The SRS airbag and seat belt pretensioner devices in your Lexus contain explosive
chemicals. If the vehicle is scrapped with the airbags and seat belt pretensioners left
as they are, this may cause an accident such as fire. Be sure to have the systems of
the SRS airbag and seat belt pretensioner removed and disposed of by a qualified
service shop or by your Lexus dealer before you scrap your vehicle.
Perchlorate Material
Special handling may apply, See www.dtsc.ca.gov/hazardouswaste/perchlorate.
Your vehicle has components that may contain perchlorate. These components may
include airbag, seat belt pretensioners, and wireless remote control batteries.
Page 25 of 543

Before driving1
23
ES350_U
1-1. Key informationKeys ............................................... 24
1-2. Opening, closing and locking the doors and
trunk
Smart access system with push-button start .................... 26
Wireless remote control ........ 38
Doors ............................................. 41
Trunk ............................................. 45
1-3. Adjustable components (seats, mirrors,
steering wheel)
Front seats ................................... 49
Driving position memory (driver’s seat) .......................... 50
Seat position memory (front passenger’s seat) ........ 54
Head restraints .......................... 56
Seat belts .................................... 58
Steering wheel........................... 64
Anti-glare inside rear view mirror ......................................... 65
Outside rear view mirrors ...... 66 1-4. Opening and closing the
windows and moon roof
Power windows .......................... 68
Moon roof .................................... 71
1-5. Refueling Opening the fuel tank cap ..... 75
1-6. Theft deterrent system Engine immobilizer system.... 78
Alarm............................................ 80
Theft prevention labels (for USA) .................................. 82
1-7. Safety information Correct driving posture ......... 83
SRS airbags ................................ 85
Front passenger occupant classification system.............. 96
Child restraint systems .......... 101
Installing child restraints....... 105
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85
1
1-7. Safety information
Before driving
ES350_U
SRS airbags
The SRS airbags inflate when the vehicle is subjected to certain types of
severe impacts that may cause significant injury to the occupants. They
work together with the seat belts to help reduce the risk of death or serious
injury.
Front airbags
Driver airbag/front passenger airbag
Can help protect the head and chest of the driver and front passen-
ger from impact with interior components.
Knee airbags
Can help provide driver and front passenger protection.
Side and curtain shield airbags
Side airbags
Can help protect the torso of the front seat occupants and rear seat
outside occupants.
Curtain shield airbags
Can help protect primarily the head of outside occupants.
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1-7. Safety information
ES350_U
Airbag system componentsYour vehicle is equipped with ADVANCED AIRBAGS designed based
on US motor vehicle safety standards (FMVSS208). The airbag system
controls airbag deployment power for the driver and front passenger. The
driver airbag system consists of the driver seat’s position sensor etc. The
front passenger’s airbag system consists of the front passenger occupant
classification sensor etc. Front passenger airbag
Curtain shield airbags
AIR BAG ON and AIR BAG
OFF indicator lights
Side airbags for the front pas-
sengers
Side and curtain shield airbag
sensors
Curtain shield airbag sensors
Side airbags for the rear out-
side passengers
SRS warning light
Driver airbag
Driver's seat position sensor
Knee airbags
Driver's seat belt buckle switch
Front passenger’s seat belt
buckle switch
Airbag sensor assembly
Occupant detection system
(ECU and sensors)
Front airbag sensors