Page 6 of 514

Contents
Instrument cluster ............................. 152
Adjusting instrument cluster
illumination .................................. 152
Coolant temperature indicator ..... 153
Trip odometer .............................. 153
Tachometer .................................. 153
Outside temperature indicator ..... 154
Control system .................................. 155
Multifunction display .................... 155
Multifunction steering wheel ........ 156
Menus .......................................... 158
Standard display menu ................ 161
AMG menu ................................... 161
AUDIO menu ................................ 165
NAV* menu .................................. 167
Distronic* menu........................... 167
Vehicle status message
memory menu .............................. 168
Settings menu .............................. 169
Trip computer menu..................... 183
TEL* menu ................................... 184
Automatic transmission ..................... 187
Gear selector lever ....................... 187
Shifting procedure ....................... 188
Gear selector lever positions ....... 189
Driving tips ................................... 191Gear ranges .................................. 192
Automatic shift program ............... 193
Gear selector lever one-touch
gearshifting ................................... 194
Steering wheel gearshift control
one-touch gearshifting E 63 AMG . 195
Manual shift program E 63 AMG ... 197
Emergency operation
(Limp-Home Mode) ....................... 199
Good visibility ..................................... 200
Headlamp cleaning system* ......... 200
Rear view mirrors .......................... 200
Sun visors ..................................... 203
Roller sunblind in the rear doors* . 204
Rear window defroster .................. 204
Dual-zone automatic climate control . 206
Deactivating the climate control
system .......................................... 211
Operating the climate control
system in automatic mode............ 211
Setting the temperature................ 212
Adjusting air distribution............... 213
Adjusting air volume ..................... 214
Front defroster.............................. 214
Maximum cooling MAX COOL
(USA only) ..................................... 216Air recirculation mode .................. 216
Air conditioning ............................ 218
Residual heat and ventilation
(Canada only)................................ 219
Rear passenger compartment
adjustable air vents ...................... 220
4-zone automatic climate control ....... 222
Deactivating the climate control
system .......................................... 227
Operating the climate control
system in automatic mode ........... 228
Setting the temperature ............... 229
Adjusting air distribution .............. 230
Adjusting air volume ..................... 231
Front defroster ............................. 231
Maximum cooling MAX COOL
(USA only) ..................................... 232
Air recirculation mode .................. 233
Air conditioning ............................ 235
Residual heat and ventilation
(Canada only)................................ 236
Rear climate control ..................... 237
Page 26 of 514
25 At a glance
Cockpit
Item
Page
1
Combination switch
Turn signals
56
Windshield wipers
57
Rear window wiper
59
High beam
56
2
Cruise control lever
Cruise control
246
Distronic*
249
3
Instrument cluster
26,
152
4
Multifunction steering
wheel
28,
156
5
Horn
6
Lever for Voice Control
System*, see separate
operating instructions
Item
Page
7
Dual-zone automatic
climate control, USA only
206
4-zone automatic climate
control*
222
8
Overhead control panel
31
9
Mobile phone/Glasses box
280
a
Glove box lid release, glove
box lock
280
b
Glove box
280
c
COMAND system, see sepa-
rate operating instructions
d
Center console
29
e
Starter switch
38
Item
Page
f
Steering wheel adjustment
stalk
45
Heated steering wheel
(Canada only)
288
g
Headlamp cleaning button*
200
h
Parking brake pedal
54, 62
j
Hood lock release
324
k
Parking brake release
54
l
Door control panel
34
m
Exterior lamp switch
141
n
Steering wheel gearshift
control (E 63 AMG only)
195
Page 110 of 514
109 Controls in detail
Locking and unlocking
Seats
Memory function
Lighting
Instrument cluster
Control system
Automatic transmission
Good visibility
Dual-zone automatic climate
control
4-zone automatic climate control
Power windows
Power tilt/sliding sunroof
Driving systems
Loading
Useful features
Page 205 of 514
204 Controls in detailGood visibilityRoller sunblind in the rear doors*
Pull the roller sunblind out using the
hooks.
Attach the hooks at the top.
Rear window defroster
The rear window defroster uses a large
amount of power. To keep the battery
drain to a minimum, switch off the
defroster as soon as the rear window is
clear. The defroster is automatically
deactivated after approximately 6 to
17 minutes of operation depending on the
outside temperature.
Switch on the ignition (
page 37).Activating
Press button1(
page 208) or
(
page 224) or buttonF
(page 209) or (
page 225) on the
respective climate control panel.
The indicator lamp on the button
comes on.
!
Always guide the sunblind by hand. Do not
let it snap back, as the retractor could be dam-
aged.
Warning!
G
Any accumulation of snow and ice should be
removed from the rear window before
driving. Visibility could otherwise be
impaired, endangering you and others.
Page 207 of 514
206 Controls in detail Dual-zone automatic climate control(only available on E 350 4MATIC)
Page 208 of 514
207 Controls in detail
Dual-zone automatic climate control
1
Thumbwheel for air volume control
for left center air vent
2
Left center air vent, adjustable
3
Cockpit air vent, fixed (Canada only)
4
Right center air vent, adjustable
5
Thumbwheel for air volume control
for right center air vent
6
Right side defroster air vent, fixed
7
Right side air vent, adjustable
8
Thumbwheel for air volume control
for right side air vent
9
Climate control panel
a
Thumbwheel for air volume control
for left side air vent
b
Left side air vent, adjustable
c
Left side defroster air vent, fixed
i
For draft-free ventilation, move the sliders
for the center air vents and side air vents to the
middle position.
Page 209 of 514
208 Controls in detailDual-zone automatic climate controlUSA only1
Temperature control, driver’s side
2
Front defroster
3
Increasing air volume
4
Display
5
Air distribution
6
Rear window defroster
7
Temperature control, passenger side
8
MAX COOL on/off
9
AC cooling on/off
a
Climate control on/off
b
Decreasing air volume
c
Air recirculation
d
Air distribution and air volume
(automatic, manual)
Page 210 of 514
209 Controls in detail
Dual-zone automatic climate control
Canada only1
Temperature control, driver’s side
2
Front defroster
3
Increasing air volume
4
Display
5
Air distribution
6
Rear window defroster
7
Temperature control, passenger side
8
Residual heat/ventilation
9
AC cooling on/off
a
Climate control on/off
b
Decreasing air volume
c
Air recirculation
d
Air distribution and air volume
(automatic, manual)